Antiplasmodial Activity of Halophilic Actinobacteria

2022 ◽  
pp. 407-412
Author(s):  
Dharumadurai Dhanasekaran ◽  
Saravanan Karthikeyan
Keyword(s):  
Antiplasmodial Activity ◽  
Halophilic Actinobacteria

HPLC based activity profiling of Ganoderma lucidum extract for antiplasmodial activity and isolation of new active lanostane triterpenoids

Planta Medica ◽  
2009 ◽  
Vol 75 (09) ◽  
Author(s):  
M Christen ◽  
M Adams ◽  
S Zimmermann ◽  
R Brun ◽  
M Hamburger
Keyword(s):  
Ganoderma Lucidum ◽  
Antiplasmodial Activity ◽  
Activity Profiling

LC-ESI-MS/MS analysis of Quassia amara leaves tea. Is antiplasmodial activity of the tea is due to quassinoids?

Planta Medica ◽  
2012 ◽  
Vol 78 (11) ◽  
Author(s):  
N Fabre ◽  
E Deharo ◽  
HL Le ◽  
C Girardi ◽  
A Valentin ◽  
...  
Keyword(s):  
Antiplasmodial Activity ◽  
Esi Ms ◽  
Ms Analysis ◽  
Quassia Amara

Bisindolomonoterpenic alkaloids from the stem bark of Strychnos Nux-Vomica exibiting antiplasmodial activity

Planta Medica ◽  
2012 ◽  
Vol 78 (11) ◽  
Author(s):  
MC Jonville ◽  
L Angenot ◽  
M Tits ◽  
M Frédérich
Keyword(s):  
Stem Bark ◽  
Antiplasmodial Activity

Antiplasmodial activity and identification of a new iridoid triacetate from Heinsia crinata

Planta Medica ◽  
2016 ◽  
Vol 81 (S 01) ◽  
pp. S1-S381
Author(s):  
TP Tshisekedi ◽  
TD Kalenda ◽  
KP Mutwale ◽  
E Cieckiewicz ◽  
O Jansen ◽  
...  
Keyword(s):  
Antiplasmodial Activity

Antiplasmodial activity of abietane diterpenes isolated from five southern African Plectranthus species

Planta Medica ◽  
2007 ◽  
Vol 73 (09) ◽  
Author(s):  
RL van Zyl ◽  
F Khan ◽  
S Drewes ◽  
T Edwards
Keyword(s):  
Antiplasmodial Activity ◽  
Abietane Diterpenes

Synthesis of Novel 1,2,3-Triazole Derivatives of Isocoumarins and 3,4-Dihydroisocoumarin with Potential Antiplasmodial Activity In Vitro

2020 ◽  
Vol 16 ◽  
Author(s):  
Lucas da Silva Santos ◽  
Matheus Fillipe Langanke de Carvalho ◽  
Ana Claudia de Souza Pinto ◽  
Amanda Luisa da Fonseca ◽  
Julio César Dias Lopes ◽  
...  
Keyword(s):  
Triazole Ring ◽  
Antiplasmodial Activity ◽  
World Health ◽  
Dipolar Cycloaddition ◽  
Terminal Alkynes ◽  
The World ◽  
Ic50 Values ◽  
Derivatives Of ◽  
Active Substances

Background: Malaria greatly affects the world health, having caused more than 228 million cases only in 2018. The emergence of drug resistance is one of the main problems in its treatment, demonstrating the urge for the development of new antimalarial drugs. Objective: Synthesis and in vitro antiplasmodial evaluation of triazole compounds derived from isocoumarins and a 3,4- dihydroisocoumarin. Method: The compounds were synthesized in 4 to 6-step reactions with the formation of the triazole ring via the Copper(I)-catalyzed 1,3-dipolar cycloaddition between isocoumarin or 3,4-dihydroisocoumarin azides and terminal alkynes. This key reaction provided compounds with an unprecedented connection of isocoumarin or 3,4-dihydroisocoumarin and the 1,2,3-triazole ring. The products were tested for their antiplasmodial activity against a Plasmodium falciparum chloroquine resistant and sensitive strains (W2 and 3D7, respectively). Results: Thirty-one substances were efficiently obtained by the proposed routes with an overall yield of 25-53%. The active substances in the antiplasmodial test displayed IC50 values ranging from 0.68-2.89 μM and 0.85-2.07 μM against W2 and 3D7 strains, respectively.

In vitro and in vivo antiplasmodial activity of novel quinoline derivative compounds by molecular hybridization

2021 ◽  
Vol 215 ◽  
pp. 113271
Author(s):  
Juliane Aparecida Marinho ◽  
Daniel Silqueira Martins Guimarães ◽  
Nícolas Glanzmann ◽  
Giovana de Almeida Pimentel ◽  
Izabelle Karine da Costa Nunes ◽  
...  
Keyword(s):  
Quinoline Derivative ◽  
Antiplasmodial Activity ◽  
Molecular Hybridization

Chemical constituents of two Cameroonian medicinal plants: Sida rhombifolia L. and Sida acuta Burm. f. (Malvaceae) and their antiplasmodial activity

2021 ◽  
pp. 1-8
Author(s):  
Blaise Cedric Kamdoum ◽  
Ingrid Simo ◽  
Steven Collins Njonte Wouamba ◽  
Brice Mariscal Tchatat Tali ◽  
Bathelemy Ngameni ◽  
...  
Keyword(s):  
Medicinal Plants ◽  
Chemical Constituents ◽  
Antiplasmodial Activity ◽  
Sida Acuta ◽  
Sida Rhombifolia

Antiplasmodial activity of triterpenoid isolated from whole plants of Viola genus from South Korea

2006 ◽  
Vol 100 (3) ◽  
pp. 641-644 ◽  
Author(s):  
Hyung-In Moon ◽  
Jae-Chul Jung ◽  
Joongku Lee
Keyword(s):  
South Korea ◽  
Antiplasmodial Activity ◽  
Whole Plants

Anti-HIV and antiplasmodial activity of original flavonoid derivatives

2010 ◽  
Vol 18 (16) ◽  
pp. 6012-6023 ◽  
Author(s):  
Gilles Casano ◽  
Aurélien Dumètre ◽  
Christophe Pannecouque ◽  
Sébastien Hutter ◽  
Nadine Azas ◽  
...  
Keyword(s):  
Antiplasmodial Activity ◽  
Anti Hiv
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