In recent years, the life course perspective has received increasing support from researchers across a number of behavioral science disciplines. The purpose of this article is to examine the relevance to social work of selected findings of the last 15 years of empirical investigation of life course concepts and themes. This discussion is organized around five basic concepts (cohorts, transitions, trajectories, life events, and turning points) and six interrelated themes (interplay of human lives and historical time, timing of lives, linked or interdependent lives, human agency in making choices, diversity in life course trajectories, and developmental risk and protection). Implications of life course theory and research for social work are overviewed.