Natural Language Processing and Systems Biology

2007 ◽  
pp. 147-173 ◽  
Author(s):  
K. Bretonnel Cohen ◽  
Lawrence Hunter
Keyword(s):  
Natural Language Processing ◽  
Systems Biology ◽  
Natural Language ◽  
Language Processing

scholarly journals Mining Inter-Relationships in Online Scientific Articles and its Visualization: Natural Language Processing for Systems Biology Modeling

2019 ◽  
Vol 15 (02) ◽  
pp. 39
Author(s):  
Nidheesh Melethadathil ◽  
Jaap Heringa ◽  
Bipin Nair ◽  
Shyam Diwakar
Keyword(s):  
Natural Language Processing ◽  
Systems Biology ◽  
Natural Language ◽  
Language Processing ◽  
Clustering Algorithms ◽  
Scientific Publications ◽  
User Query ◽  
Online Databases ◽  
Clustering Quality ◽  
Document Visualization

<strong>With the rapid growth in the numbers of scientific publications in domains such as neuroscience and medicine, visually interlinking documents in online databases such as PubMed with the purpose of indicating the context of a query results can improve the multi-disciplinary relevance of the search results. Translational medicine and systems biology rely on studies relating basic sciences to applications, often going through multiple disciplinary domains. This paper focuses on the design and development of a new scientific document visualization platform, which allows inferring translational aspects in biosciences within published articles using machine learning and natural language processing (NLP) methods. From online databases, this software platform effectively extracted relationship connections between multiple sub-domains within neuroscience derived from abstracts related to user query. In our current implementation, the document visualization platform employs two clustering algorithms namely Suffix Tree Clustering (STC) and LINGO. Clustering quality was improved by mapping top-ranked cluster labels derived from an UMLS-Metathesaurus using a scoring function. To avoid non-clustered documents, an iterative scheme, called auto-clustering was developed and this allowed mapping previously uncategorized documents during the initial grouping process to relevant clusters. The efficacy of this document clustering and visualization platform was evaluated by expert-based validation of clustering results obtained with unique search terms.  Compared to normal clustering, auto-clustering demonstrated better efficacy by generating larger numbers of unique and relevant cluster labels. Using this implementation, a Parkinson’s disease systems theory model was developed and studies based on user queries related to neuroscience and oncology have been showcased as applications.</strong>

A Review and evaluation of Machine Translation methods for Lumasaaba

2020 ◽  
pp. 3-17
Author(s):  
Peter Nabende
Keyword(s):  
Natural Language Processing ◽  
Natural Language ◽  
Machine Translation ◽  
Language Processing ◽  
Research Area ◽  
Data Driven ◽  
East African ◽  
Data Set ◽  
African Languages ◽  
Translation Methods

Natural Language Processing for under-resourced languages is now a mainstream research area. However, there are limited studies on Natural Language Processing applications for many indigenous East African languages. As a contribution to covering the current gap of knowledge, this paper focuses on evaluating the application of well-established machine translation methods for one heavily under-resourced indigenous East African language called Lumasaaba. Specifically, we review the most common machine translation methods in the context of Lumasaaba including both rule-based and data-driven methods. Then we apply a state of the art data-driven machine translation method to learn models for automating translation between Lumasaaba and English using a very limited data set of parallel sentences. Automatic evaluation results show that a transformer-based Neural Machine Translation model architecture leads to consistently better BLEU scores than the recurrent neural network-based models. Moreover, the automatically generated translations can be comprehended to a reasonable extent and are usually associated with the source language input.

1243-P: Novel Use of Natural Language Processing to Identify Reasons for Insulin Discontinuation in Patients with T2DM: A Real-World Evidence Study

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 1243-P
Author(s):  
JIANMIN WU ◽  
FRITHA J. MORRISON ◽  
ZHENXIANG ZHAO ◽  
XUANYAO HE ◽  
MARIA SHUBINA ◽  
...  
Keyword(s):  
Natural Language Processing ◽  
Natural Language ◽  
Language Processing ◽  
Real World ◽  
Real World Evidence

WHO DO WE THINK WE ARE? COMPARING INTERSECTIONAL IDENTITY TRENDS IN ASEE AND CEEA-ACEG USING NATURAL LANGUAGE PROCESSING AND REVIEW OF PROCEEDINGS

2019 ◽  
Author(s):  
Pamela Rogalski ◽  
Eric Mikulin ◽  
Deborah Tihanyi
Keyword(s):  
Natural Language Processing ◽  
Natural Language ◽  
Activity Theory ◽  
Language Processing ◽  
Division Of Labour ◽  
Cultural Historical Activity Theory ◽  
Original Question ◽  
Micro Level ◽  
Historical Activity ◽  
Cultural Historical Activity

In 2018, we overheard many CEEA-AGEC members stating that they have "found their people"; this led us to wonder what makes this evolving community unique. Using cultural historical activity theory to view the proceedings of CEEA-ACEG 2004-2018 in comparison with the geographically and intellectually adjacent ASEE, we used both machine-driven (Natural Language Processing, NLP) and human-driven (literature review of the proceedings) methods. Here, we hoped to build on surveys—most recently by Nelson and Brennan (2018)—to understand, beyond what members say about themselves, what makes the CEEA-AGEC community distinct, where it has come from, and where it is going. Engaging in the two methods of data collection quickly diverted our focus from an analysis of the data themselves to the characteristics of the data in terms of cultural historical activity theory. Our preliminary findings point to some unique characteristics of machine- and human-driven results, with the former, as might be expected, focusing on the micro-level (words and language patterns) and the latter on the macro-level (ideas and concepts). NLP generated data within the realms of "community" and "division of labour" while the review of proceedings centred on "subject" and "object"; both found "instruments," although NLP with greater granularity. With this new understanding of the relative strengths of each method, we have a revised framework for addressing our original question.  

Fast Neural Network Engine for Natural Science Language Processing: A Drug-Search Case.

2020 ◽  
Author(s):  
Vadim V. Korolev ◽  
Artem Mitrofanov ◽  
Kirill Karpov ◽  
Valery Tkachenko
Keyword(s):  
Neural Network ◽  
Natural Language Processing ◽  
Natural Language ◽  
Language Processing ◽  
Natural Science ◽  
Therapeutic Agent ◽  
Semantic Relations ◽  
Chemical Data ◽  
Processing Methods ◽  
Modern Natural

The main advantage of modern natural language processing methods is a possibility to turn an amorphous human-readable task into a strict mathematic form. That allows to extract chemical data and insights from articles and to find new semantic relations. We propose a universal engine for processing chemical and biological texts. We successfully tested it on various use-cases and applied to a case of searching a therapeutic agent for a COVID-19 disease by analyzing PubMed archive.

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