Fast Neural Network Engine for Natural Science Language Processing: A Drug-Search Case.

Author(s):  
Vadim V. Korolev ◽  
Artem Mitrofanov ◽  
Kirill Karpov ◽  
Valery Tkachenko

The main advantage of modern natural language processing methods is a possibility to turn an amorphous human-readable task into a strict mathematic form. That allows to extract chemical data and insights from articles and to find new semantic relations. We propose a universal engine for processing chemical and biological texts. We successfully tested it on various use-cases and applied to a case of searching a therapeutic agent for a COVID-19 disease by analyzing PubMed archive.

2020 ◽  
Author(s):  
Vadim V. Korolev ◽  
Artem Mitrofanov ◽  
Kirill Karpov ◽  
Valery Tkachenko

The main advantage of modern natural language processing methods is a possibility to turn an amorphous human-readable task into a strict mathematic form. That allows to extract chemical data and insights from articles and to find new semantic relations. We propose a universal engine for processing chemical and biological texts. We successfully tested it on various use-cases and applied to a case of searching a therapeutic agent for a COVID-19 disease by analyzing PubMed archive.


2020 ◽  
Author(s):  
Vadim V. Korolev ◽  
Artem Mitrofanov ◽  
Kirill Karpov ◽  
Valery Tkachenko

The main advantage of modern natural language processing methods is a possibility to turn an amorphous human-readable task into a strict mathematic form. That allows to extract chemical data and insights from articles and to find new semantic relations. We propose a universal engine for processing chemical and biological texts. We successfully tested it on various use-cases and applied to a case of searching a therapeutic agent for a COVID-19 disease by analyzing PubMed archive.


2018 ◽  
Vol 2018 ◽  
pp. 1-9 ◽  
Author(s):  
Siyuan Zhao ◽  
Zhiwei Xu ◽  
Limin Liu ◽  
Mengjie Guo ◽  
Jing Yun

Convolutional neural network (CNN) has revolutionized the field of natural language processing, which is considerably efficient at semantics analysis that underlies difficult natural language processing problems in a variety of domains. The deceptive opinion detection is an important application of the existing CNN models. The detection mechanism based on CNN models has better self-adaptability and can effectively identify all kinds of deceptive opinions. Online opinions are quite short, varying in their types and content. In order to effectively identify deceptive opinions, we need to comprehensively study the characteristics of deceptive opinions and explore novel characteristics besides the textual semantics and emotional polarity that have been widely used in text analysis. In this paper, we optimize the convolutional neural network model by embedding the word order characteristics in its convolution layer and pooling layer, which makes convolutional neural network more suitable for short text classification and deceptive opinions detection. The TensorFlow-based experiments demonstrate that the proposed detection mechanism achieves more accurate deceptive opinion detection results.


2017 ◽  
Vol 56 (05) ◽  
pp. 377-389 ◽  
Author(s):  
Xingyu Zhang ◽  
Joyce Kim ◽  
Rachel E. Patzer ◽  
Stephen R. Pitts ◽  
Aaron Patzer ◽  
...  

SummaryObjective: To describe and compare logistic regression and neural network modeling strategies to predict hospital admission or transfer following initial presentation to Emergency Department (ED) triage with and without the addition of natural language processing elements.Methods: Using data from the National Hospital Ambulatory Medical Care Survey (NHAMCS), a cross-sectional probability sample of United States EDs from 2012 and 2013 survey years, we developed several predictive models with the outcome being admission to the hospital or transfer vs. discharge home. We included patient characteristics immediately available after the patient has presented to the ED and undergone a triage process. We used this information to construct logistic regression (LR) and multilayer neural network models (MLNN) which included natural language processing (NLP) and principal component analysis from the patient’s reason for visit. Ten-fold cross validation was used to test the predictive capacity of each model and receiver operating curves (AUC) were then calculated for each model.Results: Of the 47,200 ED visits from 642 hospitals, 6,335 (13.42%) resulted in hospital admission (or transfer). A total of 48 principal components were extracted by NLP from the reason for visit fields, which explained 75% of the overall variance for hospitalization. In the model including only structured variables, the AUC was 0.824 (95% CI 0.818-0.830) for logistic regression and 0.823 (95% CI 0.817-0.829) for MLNN. Models including only free-text information generated AUC of 0.742 (95% CI 0.7310.753) for logistic regression and 0.753 (95% CI 0.742-0.764) for MLNN. When both structured variables and free text variables were included, the AUC reached 0.846 (95% CI 0.839-0.853) for logistic regression and 0.844 (95% CI 0.836-0.852) for MLNN.Conclusions: The predictive accuracy of hospital admission or transfer for patients who presented to ED triage overall was good, and was improved with the inclusion of free text data from a patient’s reason for visit regardless of modeling approach. Natural language processing and neural networks that incorporate patient-reported outcome free text may increase predictive accuracy for hospital admission.


Author(s):  
Kaan Ant ◽  
Ugur Sogukpinar ◽  
Mehmet Fatif Amasyali

The use of databases those containing semantic relationships between words is becoming increasingly widespread in order to make natural language processing work more effective. Instead of the word-bag approach, the suggested semantic spaces give the distances between words, but they do not express the relation types. In this study, it is shown how semantic spaces can be used to find the type of relationship and it is compared with the template method. According to the results obtained on a very large scale, while is_a and opposite are more successful for semantic spaces for relations, the approach of templates is more successful in the relation types at_location, made_of and non relational.


10.2196/23230 ◽  
2021 ◽  
Vol 9 (8) ◽  
pp. e23230
Author(s):  
Pei-Fu Chen ◽  
Ssu-Ming Wang ◽  
Wei-Chih Liao ◽  
Lu-Cheng Kuo ◽  
Kuan-Chih Chen ◽  
...  

Background The International Classification of Diseases (ICD) code is widely used as the reference in medical system and billing purposes. However, classifying diseases into ICD codes still mainly relies on humans reading a large amount of written material as the basis for coding. Coding is both laborious and time-consuming. Since the conversion of ICD-9 to ICD-10, the coding task became much more complicated, and deep learning– and natural language processing–related approaches have been studied to assist disease coders. Objective This paper aims at constructing a deep learning model for ICD-10 coding, where the model is meant to automatically determine the corresponding diagnosis and procedure codes based solely on free-text medical notes to improve accuracy and reduce human effort. Methods We used diagnosis records of the National Taiwan University Hospital as resources and apply natural language processing techniques, including global vectors, word to vectors, embeddings from language models, bidirectional encoder representations from transformers, and single head attention recurrent neural network, on the deep neural network architecture to implement ICD-10 auto-coding. Besides, we introduced the attention mechanism into the classification model to extract the keywords from diagnoses and visualize the coding reference for training freshmen in ICD-10. Sixty discharge notes were randomly selected to examine the change in the F1-score and the coding time by coders before and after using our model. Results In experiments on the medical data set of National Taiwan University Hospital, our prediction results revealed F1-scores of 0.715 and 0.618 for the ICD-10 Clinical Modification code and Procedure Coding System code, respectively, with a bidirectional encoder representations from transformers embedding approach in the Gated Recurrent Unit classification model. The well-trained models were applied on the ICD-10 web service for coding and training to ICD-10 users. With this service, coders can code with the F1-score significantly increased from a median of 0.832 to 0.922 (P<.05), but not in a reduced interval. Conclusions The proposed model significantly improved the F1-score but did not decrease the time consumed in coding by disease coders.


2019 ◽  
Vol 2 (8) ◽  
pp. e1910399
Author(s):  
Meliha Skaljic ◽  
Ihsaan H. Patel ◽  
Amelia M. Pellegrini ◽  
Victor M. Castro ◽  
Roy H. Perlis ◽  
...  

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