Germ Cell Transplantation and Neospermatogenesis

2011 ◽  
pp. 315-330
Author(s):  
Queenie V. Neri ◽  
Zev Rosenwaks ◽  
Zev Rosenwaks ◽  
Gianpiero D. Palermo
Keyword(s):  
Germ Cell ◽  
Cell Transplantation ◽  
Germ Cell Transplantation

scholarly journals Induced sterility in fish and its potential and challenges for aquaculture and germ cell transplantation technology: a review

Biologia ◽  
2016 ◽  
Vol 71 (8) ◽  
Author(s):  
Amin Golpour ◽  
Mohammad Abdul Momin Siddique ◽  
Diógenes Henrique Siqueira-Silva ◽  
Martin Pšenička
Keyword(s):  
Germ Cell ◽  
Cell Transplantation ◽  
Large Scale ◽  
Hormonal Treatment ◽  
Important Species ◽  
Genetic Ablation ◽  
Germ Cell Transplantation ◽  
Commercially Important ◽  
Alternative Approaches ◽  
Hormone Signalling

AbstractInterest in reproductively sterile fish in aquaculture has prompted research into their production. Several methods are available for inducing sterility and optimizing its application in the global fishery industry. Sterilization can potentially be accomplished through irradiation, surgery, or chemical and hormonal treatment. Alternative approaches include triploidization, hybridization, and generation of new lines via advanced biotechnological techniques. Triploids of many commercially important species have been studied extensively and have been produced on a large scale for many years. Novel approaches, including disruption of gonadotropin releasing hormone signalling and genetic ablation of germ cells, have been developed that are effective in producing infertile fish but have the disadvantage of not being 100% reliable or are impractical for large-scale aquaculture. We review currently used technologies and recent advances in induction of sterility in fish, especially those intended for use in germ cell transplantation. Knowledge of the implications of these approaches remains incomplete, imposing considerable limitations.

Testicular stem cells for fertility preservation: Preclinical studies on male germ cell transplantation and testicular grafting

2009 ◽  
Vol 53 (2) ◽  
pp. 274-280 ◽  
Author(s):  
Stefan Schlatt ◽  
Jens Ehmcke ◽  
Kirsi Jahnukainen
Keyword(s):  
Stem Cells ◽  
Germ Cell ◽  
Fertility Preservation ◽  
Cell Transplantation ◽  
Male Germ Cell ◽  
Preclinical Studies ◽  
Germ Cell Transplantation

scholarly journals Restoration of Fertility by Germ Cell Transplantation Requires Effective Recipient Preparation1

2003 ◽  
Vol 69 (2) ◽  
pp. 412-420 ◽  
Author(s):  
Clayton J. Brinster ◽  
Buom-Yong Ryu ◽  
Mary R. Avarbock ◽  
Levent Karagenc ◽  
Ralph L. Brinster ◽  
...  
Keyword(s):  
Germ Cell ◽  
Cell Transplantation ◽  
Germ Cell Transplantation ◽  
Restoration Of Fertility

scholarly journals Male germ cell transplantation in livestock

2006 ◽  
Vol 18 (2) ◽  
pp. 13 ◽  
Author(s):  
J. R. Hill ◽  
I. Dobrinski
Keyword(s):  
Stem Cells ◽  
Germ Cell ◽  
Cell Transplantation ◽  
Large Scale ◽  
Developmental State ◽  
Male Germ Cell ◽  
Seminiferous Tubules ◽  
Cell Transfer ◽  
Donor Sperm ◽  
Germ Cell Transplantation

Male germ cell transplantation is a powerful approach to study the control of spermatogenesis with the ultimate goal to enhance or suppress male fertility. In livestock animals, applications can be expanded to provide an alternative method of transgenesis and an alternative means of artificial insemination (AI). The transplantation technique uses testis stem cells, harvested from the donor animal. These donor stem cells are injected into seminiferous tubules, migrate from the lumen to relocate to the basement membrane and, amazingly, they can retain the capability to produce donor sperm in their new host. Adaptation of the mouse technique for livestock is progressing, with gradual gains in efficiency. Germ cell transfer in goats has produced offspring, but not yet in cattle and pigs. In goats and pigs, the applications of germ cell transplantation are mainly in facilitating transgenic animal production. In cattle, successful male germ cell transfer could create an alternative to AI in areas where it is impractical. Large-scale culture of testis stem cells would enhance the use of elite bulls by providing a renewable source of stem cells for transfer. Although still in a developmental state, germ cell transplantation is an emerging technology with the potential to create new opportunities in livestock production.

scholarly journals Germ cell transplantation and the study of testicular function

2001 ◽  
Vol 12 (1) ◽  
pp. 16-21 ◽  
Author(s):  
Derek J McLean ◽  
Daniel S Johnston ◽  
Lonnie D Russell ◽  
Michael D Griswold
Keyword(s):  
Germ Cell ◽  
Cell Transplantation ◽  
Testicular Function ◽  
Germ Cell Transplantation

Germ Cell Transplantation

2018 ◽  
pp. 171-179
Author(s):  
Hiroshi Kubota ◽  
Ralph L. Brinster
Keyword(s):  
Germ Cell ◽  
Cell Transplantation ◽  
Germ Cell Transplantation

scholarly journals New directions in assisted breeding techniques for fish conservation

2020 ◽  
Vol 32 (9) ◽  
pp. 807 ◽  
Author(s):  
Nicola Rivers ◽  
Jonathan Daly ◽  
Peter Temple-Smith
Keyword(s):  
Endangered Species ◽  
Germ Cell ◽  
Cell Transplantation ◽  
Fish Species ◽  
Captive Breeding ◽  
Germ Line ◽  
Management Strategies ◽  
Germ Cell Transplantation ◽  
Spawning Periods ◽  
Breeding Techniques

Fish populations continue to decline globally, signalling the need for new initiatives to conserve endangered species. Over the past two decades, with advances in our understanding of fish germ line biology, new exsitu management strategies for fish genetics and reproduction have focused on the use of germ line cells. The development of germ cell transplantation techniques for the purposes of propagating fish species, most commonly farmed species such as salmonids, has been gaining interest among conservation scientists as a means of regenerating endangered species. Previously, exsitu conservation methods in fish have been restricted to the cryopreservation of gametes or maintaining captive breeding colonies, both of which face significant challenges that have restricted their widespread implementation. However, advances in germ cell transplantation techniques have made its application in endangered species tangible. Using this approach, it is possible to preserve the genetics of fish species at any stage in their reproductive cycle regardless of sexual maturity or the limitations of brief annual spawning periods. Combining cryopreservation and germ cell transplantation will greatly expand our ability to preserve functional genetic samples from threatened species, to secure fish biodiversity and to produce new individuals to enhance or restore native populations.

Germ Cell Transplantation in Avian Species

2019 ◽  
pp. 317-326
Author(s):  
Young Hyun Park ◽  
Young Min Kim ◽  
Jae Yong Han
Keyword(s):  
Germ Cell ◽  
Cell Transplantation ◽  
Avian Species ◽  
Germ Cell Transplantation

Testicular Tissue Grafting and Male Germ Cell Transplantation

2012 ◽  
pp. 489-500 ◽  
Author(s):  
Jose R. Rodriguez-Sosa ◽  
Lin Tang ◽  
Ina Dobrinski
Keyword(s):  
Germ Cell ◽  
Cell Transplantation ◽  
Testicular Tissue ◽  
Male Germ Cell ◽  
Germ Cell Transplantation
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