Evaluation and Management of Benign and Malignant Adrenal Tumors

2000 ◽  
pp. 87-96
Author(s):  
Robert C. Flanigan ◽  
Fernando J. Kim
Keyword(s):  
Adrenal Tumors

Primary adrenal lymphoma in an HIV patient: a rare case of bilateral adrenal tumors

2018 ◽  
Author(s):  
Maria Mavromati ◽  
Olivier Nawej ◽  
Olga Tsopra ◽  
Heba Al-Alwan ◽  
Francois Jornayvaz ◽  
...  
Keyword(s):  
Rare Case ◽  
Adrenal Tumors ◽  
Primary Adrenal Lymphoma ◽  
Adrenal Lymphoma ◽  
Bilateral Adrenal Tumors

Hormonal secretion prevalence in a series of subjects with adrenal tumors incidentally discovered in clinical practice

2018 ◽  
Author(s):  
Carmen Gabriela Barbu ◽  
Adrian Teodor Pienary ◽  
Alice Albu ◽  
Sorina Martin ◽  
Anca Sirbu ◽  
...  
Keyword(s):  
Clinical Practice ◽  
Adrenal Tumors ◽  
Hormonal Secretion

The role of selected adipokines as predictors of excessive secretion of cortisol in patients with incidental adrenal tumors

2019 ◽  
Author(s):  
Katarzyna Reślińska ◽  
Magdalena Kuligowska-Prusińska ◽  
Roman Junik
Keyword(s):  
Adrenal Tumors ◽  
Excessive Secretion

scholarly journals Laparoscopic surgery in the treatment of rare adrenal tumors

2021 ◽  
Vol 44 (5) ◽  
pp. 759-760
Author(s):  
Shun Wan ◽  
Xiaohong Sun ◽  
Wei Chang ◽  
Jun Mi
Keyword(s):  
Laparoscopic Surgery ◽  
Adrenal Tumors

scholarly journals Can Hematological Parameters Play a Role in the Differential Diagnosis of Adrenal Tumors?

Uro ◽  
2021 ◽  
Vol 1 (2) ◽  
pp. 39-44
Author(s):  
Mehmet Gürkan Arıkan ◽  
Göktan Altuğ Öz ◽  
Nur Gülce İşkan ◽  
Necdet Süt ◽  
İlkan Yüksel ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Inflammatory Markers ◽  
Blood Count ◽  
Complete Blood Count ◽  
Low Cost ◽  
Easy Access ◽  
Adrenal Tumors ◽  
Tumor Diameter ◽  
Lymphocyte Ratio ◽  
Significant Difference

There have been few studies reported with conflicting results in the use of neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), redcell-distribution-width (RDW), etc. for predicting prognosis and differential diagnosis of adrenal tumors. The aim of this study is to investigate the role of inflammatory markers through a complete blood count, which is an easy access low-cost method, for the differential diagnosis of adrenocortical adenoma (ACA), adrenocortical carcinoma (ACC), and pheochromocytoma. The data of patients who underwent adrenalectomy between the years of 2010–2020 were retrospectively analyzed. Systemic hematologic inflammatory markers based on a complete blood count such as neutrophil ratio (NR), lymphocyte ratio (LR), NLR, PLR, RDW, mean platelet volume (MPV), and maximum tumor diameter (MTD) were compared between the groups. A statistically significant difference was found between the three groups in terms of PLR, RDW, and MTD. With post-hoc tests, a statistically significant difference was found in PLR and MTD between the ACA and ACC groups. A statistically significant difference was found between the ACA and pheochromocytoma groups in PLR and RDW values. In conclusion, it could be possible to plan a more accurate medical and surgical approach using PLR and RDW, which are easily calculated through an easy access low-cost method such as a complete blood count, together with MTD in the differential diagnosis of ACC, ACA, and pheochromocytoma.

scholarly journals High Diagnostic and Prognostic Value of Steroidogenic Factor-1 Expression in Adrenal Tumors

Endocrinology ◽  
2010 ◽  
Vol 151 (8) ◽  
pp. 4066-4066
Author(s):  
Silviu Sbiera ◽  
Sebastian Schmull ◽  
Guillaume Assie ◽  
Hans-Ullrich Voelker ◽  
Luitgard Kraus ◽  
...  
Keyword(s):  
Prognostic Value ◽  
Adrenal Tumors ◽  
Steroidogenic Factor 1 ◽  
Diagnostic And Prognostic Value

scholarly journals Differentiating Benign from Malignant Adrenocortical Tumors by a Single Morphological Parameter—a Clinicopathological Study on 837 Adrenocortical Neoplasias

2020 ◽  
Vol 11 (4) ◽  
pp. 705-710
Author(s):  
Martin K. Walz ◽  
Klaus A. Metz ◽  
Sarah Theurer ◽  
Cathrin Myland ◽  
Pier F. Alesina ◽  
...  
Keyword(s):  
Adrenocortical Carcinoma ◽  
Tumor Necrosis ◽  
Morphological Differentiation ◽  
Scoring Systems ◽  
Distant Metastases ◽  
Adrenal Tumors ◽  
Control Group ◽  
Consecutive Series ◽  
Morphological Parameter ◽  
Adrenocortical Tumors

AbstractThe morphological differentiation between benign and malignant adrenocortical tumors is an ongoing problem in diagnostic pathology. In recent decades the complex scoring systems have been widely used to calculate the probability of malignancy in adrenocortical tumors on the basis of a variety of histomorphological parameters. We herewith present a substantially simplified method to diagnose adrenocortical carcinoma by a single histomorphological parameter on a consecutive series of more than 800 adrenocortical tumors. Between January 2000 and May 2019, altogether 2305 adrenalectomies for of all types of diseases were removed, approximately 98% by minimally invasive approaches. After exclusion of pheochromocytomas, adrenal ganglioneuromas, adrenal metastases, Cushing’s disease related specimens, and Conn’s adenomas, the present series finally consisted of 837 adrenocortical tumors. All tumors were analyzed by experienced pathologists of a single institution using standard histopathological methods (Hematoxylin-Eosin and Ki67 stained sections). Clinical and histopathologic data were prospectively collected and retrospectively analyzed. Clinically, 385 patients had 420 functioning tumors (FT), and 417 had non-functioning adrenal tumors (NFT). The mean size of FT was 3.8 ± 1.4 cm (range 0.5–16 cm) and for NFT 4.5 ± 1.6 cm (range 1.5–18 cm). Histomorphologically, 32 adrenal tumors were classified as adrenocortical carcinoma (ACC; 3.8%). In all 32 cases (tumor size 9.1 ± 4.0 cm, range 3–18 cm), confluenting tumor necrosis could be demonstrated. The remaining 805 tumors (control group) completely lacked this highly reproducible single morphological feature. Ki67 levels above 10% were found in 31 of 32 ACCs and never in adrenocortical adenomas (ACA). With a mean follow-up of 8.2 years, 24 out of 32 patients primarily diagnosed as ACC developed distant metastases (75.0%), whereas all patients in the control group remained free of local or distant recurrence. We conclude that a single morphological parameter (confluenting tumor necrosis) is sufficient to predict a poor clinical course in adrenocortical tumors. The histomorphological diagnosis of this parameter is straightforward and highly reproducible.

Adrenal Tumors in Childhood

2021 ◽  
Vol 68 ◽  
pp. 227-244
Author(s):  
John S. Fuqua
Keyword(s):  
Adrenal Tumors
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