Large Scale Screening Programs in Breast Cancer Prevention

1988 ◽  
pp. 349-355
Author(s):  
L. Tabár
Keyword(s):  
Breast Cancer ◽  
Cancer Prevention ◽  
Large Scale ◽  
Breast Cancer Prevention ◽  
Screening Programs ◽  
Large Scale Screening

scholarly journals The Role of NSAIDs in Breast Cancer Prevention and Relapse: Current Evidence and Future Perspectives

Breast Care ◽  
2016 ◽  
Vol 11 (5) ◽  
pp. 339-344 ◽  
Author(s):  
Demetrios Moris ◽  
Michalis Kontos ◽  
Eleftherios Spartalis ◽  
Ian S. Fentiman
Keyword(s):  
Breast Cancer ◽  
Cancer Prevention ◽  
Large Scale ◽  
Clinical Investigation ◽  
Breast Cancer Incidence ◽  
Breast Cancer Prevention ◽  
Current Evidence ◽  
Dose Frequency ◽  
Chemopreventive Agents

Aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) have received considerable interest as potential chemopreventive agents. The aim of this review is to summarize the accumulated knowledge on the effect of NSAIDs on breast cancer incidence and natural history, and the underlying pathophysiology. NSAIDs mainly block inflammation by inhibiting cyclooxygenase enzymes, leading to lower prostaglandin synthesis. The latter has been reported to affect breast cancer risk through hormonal and inflammation-related pathways. Intensity, dose, frequency, duration, and timing of administration may also be significant. There is currently enough evidence to support a role of NSAIDs in breast cancer prevention and relapse, which deserves further large-scale experimental and clinical investigation.

Delays in presentation and treatment of breast cancer in Nigeria

2009 ◽  
Vol 27 (15_suppl) ◽  
pp. 1527-1527 ◽  
Author(s):  
R. E. Ezeome
Keyword(s):  
Breast Cancer ◽  
Cancer Prevention ◽  
Primary Care Physicians ◽  
Breast Cancer Prevention ◽  
Definitive Treatment ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Screening Programs ◽  
Initial Hospital ◽  
Breast Awareness

1527 Background: Programs on breast cancer prevention inresource poor countries often emphasize cost effective interventions to increase the uptake of screening, breast awareness, and the use of breast self examination. The success of such programs depends on the response of women and health professionals to the presence of symptoms of breast cancer. Understanding the factors at play in these responses is a prerequisite for strategies to shorten delays and improve stage at diagnosis. This study was designed to assess the delays and define the causes of delays in getting medical treatment by patients with breast cancer at University of Nigeria Teaching Hospital Enugu, (UNTH-E), Nigeria. Methods: A cross-sectional survey of consecutively presenting patients with breast cancer at the Surgical Oncology unit of the UNTH-E, Nigeria, was carried out between June 1999 and May 2005. A structured questionnaire was used to explore delays and the factors that influence delays in presentation and treatment of breast cancer. Results: One hundred and sixty four patients with breast cancer were interviewed. Most of them were married (71.2%), literate (84.7%), low (58.8%) or middle socioeconomic class (40%), and had access to hospitals within their area of residence. Most (81.6%) reported first for treatment at a modern health facility while 17.5% used alternative practitioners first. Twenty-six percent (42) presented within a month of noticing the symptoms while 45.3% (72) delayed for 3 months or more. In contrast, 17% (18) were seen at the site of definitive treatment within 1 month of seeking help at the initial hospital while 73.4% had a delay of more than 3 months after the initial hospital contact. Institutional or physician related delays were present in 44.5% of the cases while patient-related delays were present in 76.7% of cases. Only use of alternative practitioners as the first treatment point was significantly related to delays of more than 3 months before presentation (p = 0.029). Conclusions: For breast cancer prevention programs in Nigeria to succeed, they must, in addition to breast awareness and screening programs, address the institutional bottlenecks, the dearth of knowledge among primary care physicians, and improved referrals from alternative practitioners. No significant financial relationships to disclose.

scholarly journals Doing What We Know, Knowing What to Do: Californians Linking Action with Science for Prevention of Breast Cancer (CLASP-BC)

2020 ◽  
Vol 17 (14) ◽  
pp. 5050 ◽  
Author(s):  
Jon F. Kerner ◽  
Marion H. E. Kavanaugh-Lynch ◽  
Lourdes Baezconde-Garbanati ◽  
Christopher Politis ◽  
Aviva Prager ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Prevention ◽  
Large Scale ◽  
Underserved Populations ◽  
Research Training ◽  
Phase 1 ◽  
Breast Cancer Prevention ◽  
Dissemination And Implementation ◽  
Successful Implementation ◽  
Prevention Of Breast Cancer

Given the lack of progress in breast cancer prevention, the California Breast Cancer Research Program (CBCRP) plans to apply current scientific knowledge about breast cancer to primary prevention at the population level. This paper describes the first phase of Californians Linking Action with Science for Prevention of Breast Cancer (CLASP-BC). The foci of Phase 1 are building coalitions and coalition capacity building through community engagement in community-based participatory research (CBPR) and dissemination and implementation (D&I) research training. Based on the successful implementation and evaluation of Phase 1, the foci of Phase 2 (presented separately in this special issue) will be to translate the California Breast Cancer Prevention Plan overarching goal and specific intervention goals for 23 breast cancer risk and protective factors strategies into evidence-informed interventions (EIIs) that are disseminated and implemented across California. CLASP-BC is designed to identify, disseminate and implement high-impact, population-based prevention approaches by funding large scale EIIs, through multi-jurisdictional actions, with the intent to decrease the risk of breast cancer and other chronic diseases (sharing common risk factors), particularly among racial/ethnic minorities and medically underserved populations in California.

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