Receptor Tyrosine Kinases in the Nucleus: Nuclear Functions and Therapeutic Implications in Cancers

Nuclear Signaling Pathways and Targeting Transcription in Cancer - Cancer Drug Discovery and Development ◽

10.1007/978-1-4614-8039-6_8 ◽

2013 ◽

pp. 189-229 ◽

Author(s):

Longfei Huo ◽

Jennifer L. Hsu ◽

Mien-Chie Hung

Keyword(s):

Tyrosine Kinases ◽

Receptor Tyrosine Kinases ◽

Therapeutic Implications

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CSIG-07EGFRvIII MEDIATED TRANSACTIVATION OF RECEPTOR TYROSINE KINASES IN GLIOMA: MECHANISM AND THERAPEUTIC IMPLICATIONS

Neuro-Oncology ◽

10.1093/neuonc/nov210.07 ◽

2015 ◽

Vol 17 (suppl 5) ◽

pp. v67.3-v67

Author(s):

Terrance Johns ◽

Sam Greenall ◽

Jacqui Donoghue ◽

Tim Adams

Keyword(s):

Tyrosine Kinases ◽

Receptor Tyrosine Kinases ◽

Therapeutic Implications

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Receptor tyrosine kinases (RTKs) in breast cancer: signaling, therapeutic implications and challenges

Molecular Cancer ◽

10.1186/s12943-018-0797-x ◽

2018 ◽

Vol 17 (1) ◽

Author(s):

Ramesh Butti ◽

Sumit Das ◽

Vinoth Prasanna Gunasekaran ◽

Amit Singh Yadav ◽

Dhiraj Kumar ◽

...

Keyword(s):

Breast Cancer ◽

Tyrosine Kinases ◽

Receptor Tyrosine Kinases ◽

Therapeutic Implications ◽

Cancer Signaling

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Therapeutic Implications of Detection of Amplification and Activation of HER2 and Other Receptor Tyrosine Kinases (RTKs) in Circulating Tumor Cells (CTCs) in Recurrent Breast Cancer.

10.1158/0008-5472.sabcs-09-3010 ◽

2009 ◽

Author(s):

P. Kim ◽

X. Liu ◽

L. Liu ◽

T. Lee ◽

R. Barham ◽

...

Keyword(s):

Breast Cancer ◽

Tumor Cells ◽

Circulating Tumor Cells ◽

Tyrosine Kinases ◽

Receptor Tyrosine Kinases ◽

Recurrent Breast Cancer ◽

Therapeutic Implications ◽

Recurrent Breast

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EGFRvIII-mediated transactivation of receptor tyrosine kinases in glioma: mechanism and therapeutic implications

Oncogene ◽

10.1038/onc.2014.448 ◽

2015 ◽

Vol 34 (41) ◽

pp. 5277-5287 ◽

Author(s):

S A Greenall ◽

J F Donoghue ◽

M Van Sinderen ◽

V Dubljevic ◽

S Budiman ◽

...

Keyword(s):

Tyrosine Kinases ◽

Receptor Tyrosine Kinases ◽

Therapeutic Implications

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762: Differential Regulation of EPHB4 and EPHB2 Receptor Tyrosine Kinases in Normal Bladder and Bladder Transitional Cell Carcinoma

The Journal of Urology ◽

10.1016/s0022-5347(18)31002-4 ◽

2007 ◽

Vol 177 (4S) ◽

pp. 256-256

Author(s):

Wesley W. Choi ◽

Jeff S. Scehnet ◽

S. Ram Kumar ◽

Charlotte C. Lee ◽

Anne Schuckman ◽

...

Keyword(s):

Transitional Cell Carcinoma ◽

Cell Carcinoma ◽

Tyrosine Kinases ◽

Receptor Tyrosine Kinases ◽

Transitional Cell ◽

Differential Regulation ◽

Bladder Transitional Cell Carcinoma ◽

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Increasing PARP inhibitor efficacy in ovarian cancer by targeting receptor tyrosine kinases

10.1055/s-0040-1718153 ◽

2020 ◽

Author(s):

D.M Klotz ◽

J.D Kuhlmann ◽

P Wimberger

Keyword(s):

Ovarian Cancer ◽

Tyrosine Kinases ◽

Receptor Tyrosine Kinases ◽

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Faculty Opinions recommendation of Multiple EphB receptor tyrosine kinases shape dendritic spines in the hippocampus.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1001498.201400 ◽

2003 ◽

Author(s):

Guoping Feng

Keyword(s):

Dendritic Spines ◽

Tyrosine Kinases ◽

Receptor Tyrosine Kinases ◽

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Faculty Opinions recommendation of E-cadherin-mediated adhesion inhibits ligand-dependent activation of diverse receptor tyrosine kinases.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1018427.208497 ◽

2004 ◽

Author(s):

Kathleen J Green

Keyword(s):

Tyrosine Kinases ◽

Receptor Tyrosine Kinases ◽

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Faculty Opinions recommendation of Genome-wide analyses identify recurrent amplifications of receptor tyrosine kinases and cell-cycle regulatory genes in diffuse intrinsic pontine glioma.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.13355984.14726088 ◽

2011 ◽

Author(s):

John Maris ◽

David Teachey

Keyword(s):

Tyrosine Kinases ◽

Receptor Tyrosine Kinases ◽

Diffuse Intrinsic Pontine Glioma ◽

Regulatory Genes ◽

Pontine Glioma ◽

Genome Wide ◽

Cell Cycle Regulatory Genes

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Faculty Opinions recommendation of Allosteric inhibition of SHP2 phosphatase inhibits cancers driven by receptor tyrosine kinases.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.726472311.793521055 ◽

2016 ◽

Author(s):

Xiayang Qiu ◽

Ye Che

Keyword(s):

Tyrosine Kinases ◽

Receptor Tyrosine Kinases ◽

Allosteric Inhibition

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