Diagnostic Usefulness of Serum Bile Acid Determination in Liver Diseases

1985 ◽  
pp. 81-85
Author(s):  
L. Barbara ◽  
D. Festi ◽  
A. Roda ◽  
A. M. Morselli Labate ◽  
B. Grigolo ◽  
...  
Keyword(s):  
Bile Acid ◽  
Liver Diseases ◽  
Serum Bile Acid ◽  
Diagnostic Usefulness ◽  
Acid Determination

Clinical significance of serum bile acid measurement in liver diseases

1978 ◽  
Vol 13 (6) ◽  
pp. 491-502 ◽  
Author(s):  
Tomofumi Morita ◽  
Yoshinori Matsuyama ◽  
Takayoshi Fujimoto ◽  
Masaru Higuchi ◽  
Tadasu Tsujii ◽  
...  
Keyword(s):  
Bile Acid ◽  
Clinical Significance ◽  
Liver Diseases ◽  
Serum Bile Acid

scholarly journals Analysis of the Serum Bile Acid Composition for Differential Diagnosis in Patients with Liver Disease

2015 ◽  
Vol 2015 ◽  
pp. 1-10 ◽  
Author(s):  
Tomonori Sugita ◽  
Katsushi Amano ◽  
Masanori Nakano ◽  
Noriko Masubuchi ◽  
Masahiro Sugihara ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Liver Disease ◽  
Bile Acid ◽  
Viral Hepatitis ◽  
Healthy Volunteers ◽  
Biliary Tract ◽  
Liver Diseases ◽  
Biliary Tract Disease ◽  
Serum Bile Acid ◽  
Biliary Tract Diseases

Objectives. We determined the serum bile acid (BA) composition in patients with liver diseases and healthy volunteers to investigate the relationship between the etiologies of liver disease and BA metabolism.Material and Methods. Sera from 150 patients with liver diseases and 46 healthy volunteers were obtained. The serum concentrations of the 16 different BAs were determined according to the LC-MS/MS method and were compared between the different liver diseases.Results. A total of 150 subjects, including patients with hepatitis C virus (HCV) (n=44), hepatitis B virus (HBV) (n=23), alcoholic liver disease (ALD) (n=21), biliary tract disease (n=20), nonalcoholic fatty liver disease (NAFLD) (n=13), and other liver diseases (n=29), were recruited. The levels of UDCA and GUDCA were significantly higher in the ALD group, and the levels of DCA and UDCA were significantly lower in the biliary tract diseases group than in viral hepatitis group. In the UDCA therapy (−) subgroup, a significantly lower level of TLCA was observed in the ALD group, with lower levels of CDCA, DCA, and GLCA noted in biliary tract diseases group compared to viral hepatitis group.Conclusions. Analysis of the BA composition may be useful for differential diagnosis in liver disease.

Serum Bile Acid Determination after Different Doses of Orally Ingested Chenodeoxycholic Acid: Evaluation of a Simplified Enzymatic Method

1985 ◽  
Vol 20 (10) ◽  
pp. 1221-1226 ◽  
Author(s):  
H. Tanghöj ◽  
U. Foberg ◽  
A. Frydén ◽  
B. Kågedal ◽  
L. Pettersson ◽  
...  
Keyword(s):  
Bile Acid ◽  
Chenodeoxycholic Acid ◽  
Serum Bile Acid ◽  
Enzymatic Method ◽  
Different Doses ◽  
Acid Determination

scholarly journals Evaluation of the Diagnostic Value of Serum Bile Acid in the Detection and Functional Assessment of Liver Diseases

1985 ◽  
Vol 22 (6) ◽  
pp. 596-605 ◽  
Author(s):  
C. Cravetto ◽  
G. Molino ◽  
A. M. Biondi ◽  
A. Cavanna ◽  
P. Avagnina ◽  
...  
Keyword(s):  
Bile Acid ◽  
Functional Assessment ◽  
Liver Diseases ◽  
Diagnostic Value ◽  
Serum Bile Acid

Clinical Value of Serum Bile Acid Determination

1987 ◽  
pp. 28-47
Author(s):  
G. A. Mannes ◽  
F. Stellaard ◽  
G. Paumgartner
Keyword(s):  
Bile Acid ◽  
Serum Bile Acid ◽  
Clinical Value ◽  
Acid Determination

scholarly journals Clinical Significance of Serum Bile Acid Fraction in Liver Diseases as Analyzed by Enzyme-linked Immunosorbent Assay

1995 ◽  
Vol 7 (1) ◽  
pp. 33-47
Author(s):  
Motonari KANO ◽  
Hiroshi WADA ◽  
Koki MOTEGI ◽  
Yusaku KANO ◽  
Masaru MATSUMOTO ◽  
...  
Keyword(s):  
Bile Acid ◽  
Clinical Significance ◽  
Immunosorbent Assay ◽  
Liver Diseases ◽  
Enzyme Linked Immunosorbent Assay ◽  
Serum Bile Acid ◽  
Acid Fraction

Development of a disposable bile acid biosensor for use in the management of cholestasis

2015 ◽  
Vol 7 (9) ◽  
pp. 3714-3719 ◽  
Author(s):  
D. Lawrance ◽  
C. Williamson ◽  
M. G. Boutelle ◽  
A. E. G. Cass
Keyword(s):  
Bile Acid ◽  
Acid Concentration ◽  
Intrahepatic Cholestasis ◽  
Liver Diseases ◽  
Serum Bile Acid ◽  
Intrahepatic Cholestasis Of Pregnancy ◽  
Bile Acid Concentration ◽  
Cholestasis Of Pregnancy

Measurement of serum bile acid concentration is a valuable tool for the management of intrahepatic cholestasis of pregnancy (ICP) and is also useful in the monitoring of other liver diseases.

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