Computer Simulation of Cardiac Excitation

1982 ◽  
pp. 35-41 ◽  
Author(s):  
I. Ruttkay-Nedecký ◽  
V. Szathmáry ◽  
P. Chlebus ◽  
A. Ruttkay-Nedecká
Keyword(s):  
Computer Simulation ◽  
Cardiac Excitation

scholarly journals Teaching cardiac excitation-contraction coupling using a mathematical computer simulation model of human ventricular myocytes

2020 ◽  
Vol 44 (3) ◽  
pp. 323-333
Author(s):  
Young Keul Jeon ◽  
Jae Boum Youm ◽  
Kotdaji Ha ◽  
JooHan Woo ◽  
Hae Young Yoo ◽  
...  
Keyword(s):  
Computer Simulation ◽  
Simulation Model ◽  
Ventricular Myocytes ◽  
Learning Goals ◽  
Computer Simulation Model ◽  
National University ◽  
Detailed Assessment ◽  
Problem Solving Process ◽  
Seoul National University ◽  
Cardiac Excitation

To understand the excitation-contraction (E-C) coupling of cardiomyocytes, including the electrophysiological mechanism of their characteristically long action potential duration, is one of the major learning goals in medical physiology. However, the integrative interpretation of the responses occurring during the contraction-relaxation cycle is challenging due to the dynamic interaction of underlying factors. Starting in 2017, we adopted the mathematical computer simulation model of human ventricular myocyte (Cardiac E-C_Sim), hypothesizing that this educational technology may facilitate students’ learning of cardiac physiology. Here, we describe the overall process for the educational application of Cardiac E-C_Sim in the human physiology practicum of Seoul National University College of Medicine. We also report the results from questionnaires covering detailed assessment of the practicum class. The analysis of results and feedback opinions enabled us to understand how the students had approached the problem-solving process. As a whole, the students could better accomplish the learning goals using Cardiac E-C_Sim, followed by constructive discussions on the complex and dynamic mechanisms of cardiac E-C coupling. We suggest that the combined approach of lecture-based teaching and computer simulations guided by a manual containing clinical context would be broadly applicable in physiology education.

Characterization of Modulated Structure Through Structure Images and their Computer Simulation

1990 ◽  
Vol 48 (1) ◽  
pp. 70-71
Author(s):  
Kiyomichi Nakai ◽  
Yusuke Isobe ◽  
Chiken Kinoshita ◽  
Kazutoshi Shinohara
Keyword(s):  
Computer Simulation ◽  
High Resolution ◽  
Spherical Aberration ◽  
High Resolution Electron Microscopy ◽  
Basic Mechanism ◽  
Objective Lens ◽  
Specimen Thickness ◽  
Transmitted Beam ◽  
Modulated Structure ◽  
Resolution Electron

Induced spinodal decomposition under electron irradiation in a Ni-Au alloy has been investigated with respect to its basic mechanism and confirmed to be caused by the relaxation of coherent strain associated with modulated structure. Modulation of white-dots on structure images of modulated structure due to high-resolution electron microscopy is reduced with irradiation. In this paper the atom arrangement of the modulated structure is confirmed with computer simulation on the structure images, and the relaxation of the coherent strain is concluded to be due to the reduction of phase-modulation.Structure images of three-dimensional modulated structure along <100> were taken with the JEM-4000EX high-resolution electron microscope at the HVEM Laboratory, Kyushu University. The transmitted beam and four 200 reflections with their satellites from the modulated structure in an fee Ni-30.0at%Au alloy under illumination of 400keV electrons were used for the structure images under a condition of the spherical aberration constant of the objective lens, Cs = 1mm, the divergence of the beam, α = 3 × 10-4 rad, underfocus, Δf ≃ -50nm and specimen thickness, t ≃ 15nm. The CIHRTEM code was used for the simulation of the structure image.

Computer simulation of a dental practice using therapists

1972 ◽  
Vol 36 (6) ◽  
pp. 35-39
Author(s):  
JB Dilworth ◽  
WJ Pelton
Keyword(s):  
Computer Simulation ◽  
Dental Practice

Averting robo-bees: why free-flying robotic bees are a bad idea

2019 ◽  
Vol 3 (6) ◽  
pp. 723-729
Author(s):  
Roslyn Gleadow ◽  
Jim Hanan ◽  
Alan Dorin
Keyword(s):  
Climate Change ◽  
Computer Simulation ◽  
Food Security ◽  
European Countries ◽  
Plant Interactions ◽  
Plant Insect Interactions ◽  
Native Habitat ◽  
Insect Pollinators ◽  
Insect Interactions

Food security and the sustainability of native ecosystems depends on plant-insect interactions in countless ways. Recently reported rapid and immense declines in insect numbers due to climate change, the use of pesticides and herbicides, the introduction of agricultural monocultures, and the destruction of insect native habitat, are all potential contributors to this grave situation. Some researchers are working towards a future where natural insect pollinators might be replaced with free-flying robotic bees, an ecologically problematic proposal. We argue instead that creating environments that are friendly to bees and exploring the use of other species for pollination and bio-control, particularly in non-European countries, are more ecologically sound approaches. The computer simulation of insect-plant interactions is a far more measured application of technology that may assist in managing, or averting, ‘Insect Armageddon' from both practical and ethical viewpoints.

Computer simulation of the far infrared collision induced absorption spectra of gaseous CO2

1998 ◽  
Vol 93 (6) ◽  
pp. 1007-1016 ◽  
Author(s):  
MARCIN GRUSZKA ◽  
ALEKSANDRA BORYSOW
Keyword(s):  
Computer Simulation ◽  
Absorption Spectra ◽  
Far Infrared ◽  
Induced Absorption

Review of Computer Simulation Techniques.

1967 ◽  
Vol 12 (3) ◽  
pp. 175-175
Author(s):  
JOHN C. LOEHLIN
Keyword(s):  
Computer Simulation ◽  
Simulation Techniques ◽  
Computer Simulation Techniques

So You Want to Write a Computer Simulation

1978 ◽  
Vol 23 (9) ◽  
pp. 649-650
Author(s):  
ARTHUR M. FARLEY
Keyword(s):  
Computer Simulation
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