Purine Degradation in Contracting Fast and Slow Muscles of Rats

Author(s):  
Naoko Hara ◽  
Ikuo Mineo ◽  
Yuya Yamada ◽  
Masanori Kawachi ◽  
Hiroaki Kiyokawa ◽  
...  
1983 ◽  
Vol 398 (1) ◽  
pp. 48-54 ◽  
Author(s):  
Raimund Sterz ◽  
Murali Pagala ◽  
Klaus Peper

Author(s):  
John D. Altringham ◽  
Terry Morris ◽  
Rob S. James ◽  
Chris I. Smith

2000 ◽  
Vol 279 (5) ◽  
pp. C1558-C1563 ◽  
Author(s):  
Laurence Stevens ◽  
Carole Firinga ◽  
Bärbel Gohlsch ◽  
Bruno Bastide ◽  
Yvonne Mounier ◽  
...  

To investigate the plasticity of slow and fast muscles undergoing slow-to-fast transition, rat soleus (SOL), gastrocnemius (GAS), and extensor digitorum longus (EDL) muscles were exposed for 14 days to 1) unweighting by hindlimb suspension (HU), or 2) treatment with the β2-adrenergic agonist clenbuterol (CB), or 3) a combination of both (HU-CB). In general, HU elicited atrophy, CB induced hypertrophy, and HU-CB partially counteracted the HU-induced atrophy. Analyses of myosin heavy (MHC) and light chain (MLC) isoforms revealed HU- and CB-induced slow-to-fast transitions in SOL (increases of MHCIIa with small amounts of MHCIId and MHCIIb) and the upregulation of the slow MHCIa isoform. The HU- and CB-induced changes in GAS consisted of increases in MHCIId and MHCIIb (“fast-to-faster transitions”). Changes in the MLC composition of SOL and GAS consisted of slow-to-fast transitions and mainly encompassed an exchange of MLC1s with MLC1f. In addition, MLC3f was elevated whenever MHCIId and MHCIIb isoforms were increased. Because the EDL is predominantly composed of type IID and IIB fibers, HU, CB, and HU-CB had no significant effect on the MHC and MLC patterns.


Neonatology ◽  
1990 ◽  
Vol 58 (6) ◽  
pp. 311-317 ◽  
Author(s):  
Kim Vettenranta ◽  
Kari O. Raivio

1997 ◽  
Vol 7 (6-7) ◽  
pp. 475
Author(s):  
Erno Zador ◽  
Luca Mendler ◽  
Gerda Szakonyi ◽  
Gabor Racz ◽  
Aniko Gorbe ◽  
...  

Nephron ◽  
1993 ◽  
Vol 64 (3) ◽  
pp. 481-482 ◽  
Author(s):  
Hiromoto Kosaka ◽  
Ichiro Hisatome ◽  
Kazuhíde Oginö ◽  
Yasushi Tanaka ◽  
Shuichi Osaki ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document