Role of Hemoglobin Denaturation and Band 3 Clustering in Initiating Red Cell Removal

1991 ◽  
pp. 173-183 ◽  
Author(s):  
Philip S. Low
Keyword(s):  
Band 3 ◽  
Red Cell

The orientation of sickle hemoglobin fibers within fascicles

1988 ◽  
Vol 46 ◽  
pp. 400-401
Author(s):  
Christopher A. Miller ◽  
Bridget Carragher ◽  
William A. McDade ◽  
Robert Josephs
Keyword(s):  
Sickle Cell ◽  
Sickle Cell Anemia ◽  
Relative Orientation ◽  
Unit Cell ◽  
Red Cell ◽  
High Ph ◽  
Sickle Hemoglobin ◽  
Polar Crystal ◽  
Helical Configuration

Highly ordered bundles of deoxyhemoglobin S (HbS) fibers, termed fascicles, are intermediates in the high pH crystallization pathway of HbS. These fibers consist of 7 Wishner-Love double strands in a helical configuration. Since each double strand has a polarity, the odd number of double strands in the fiber imparts a net polarity to the structure. HbS crystals have a unit cell containing two double strands, one of each polarity, resulting in a net polarity of zero. Therefore a rearrangement of the double strands must occur to form a non-polar crystal from the polar fibers. To determine the role of fascicles as an intermediate in the crystallization pathway it is important to understand the relative orientation of fibers within fascicles. Furthermore, an understanding of fascicle structure may have implications for the design of potential sickling inhibitors, since it is bundles of fibers which cause the red cell distortion responsible for the vaso-occlusive complications characteristic of sickle cell anemia.

Use of a Red Cell Band 3-Ligand/Antioxidant to Improve Red Cell Storage Properties Following Virucidal Phototeatment with Chalcogenoxanthylium Photosensitizers

2006 ◽  
Vol 82 (6) ◽  
pp. 1595
Author(s):  
Stephen J. Wagner ◽  
Andrey Skripchenko ◽  
Dedeene Thompson-Montgomery ◽  
Helen Awatefe ◽  
David J. Donnelly ◽  
...  
Keyword(s):  
Band 3 ◽  
Red Cell ◽  
Storage Properties ◽  
Cell Storage

scholarly journals Band 3, the human red cell chloride/bicarbonate anion exchanger (AE1, SLC4A1), in a structural context

2016 ◽  
Vol 1858 (7) ◽  
pp. 1507-1532 ◽  
Author(s):  
Reinhart A.F. Reithmeier ◽  
Joseph R. Casey ◽  
Antreas C. Kalli ◽  
Mark S.P. Sansom ◽  
Yilmaz Alguel ◽  
...  
Keyword(s):  
Anion Exchanger ◽  
Band 3 ◽  
Red Cell ◽  
Structural Context

Fine structure of the band 3 protein in human red cell membranes: Freeze-fracture studies

1978 ◽  
Vol 8 (3) ◽  
pp. 325-335 ◽  
Author(s):  
Ronald S. Weinstein ◽  
Jena K. Khodadad ◽  
Theodore L. Steck
Keyword(s):  
Fine Structure ◽  
Cell Membranes ◽  
Freeze Fracture ◽  
Band 3 ◽  
Red Cell ◽  
Band 3 Protein ◽  
Red Cell Membranes

scholarly journals Role of Red Cell Distribution Width in the Relationship between Clinical Outcomes and Anticoagulation Response in Patients with Atrial Fibrillation

2018 ◽  
Vol 54 (2) ◽  
pp. 113 ◽  
Author(s):  
Ki Hong Lee ◽  
Jeong Gwan Cho ◽  
Hyung Wook Park ◽  
Nam Sik Yoon ◽  
Hyung Ki Jeong ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Clinical Outcomes ◽  
Red Cell Distribution Width ◽  
Red Cell ◽  
Cell Distribution ◽  
Distribution Width ◽  
The Relationship
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