Molecular and Cellular Events in Myocardial Hypertrophy and Failure

2005 ◽  
pp. 61-81
Author(s):  
Douglas B. Sawyer ◽  
Wilson S. Colucci
2002 ◽  
pp. 65-85
Author(s):  
Douglas B. Sawyer ◽  
Wilson S. Colucci

2003 ◽  
Vol 2 (1) ◽  
pp. 36
Author(s):  
K STANGL ◽  
H DREGER ◽  
V STANGL ◽  
G BAUMANN ◽  
S MEINERS

Therapy ◽  
2005 ◽  
Vol 2 (3) ◽  
pp. 415-423
Author(s):  
Antony Halapas ◽  
Peter Lembessis ◽  
Antigone Sourla ◽  
Costas Pantos ◽  
Dennis V Cokkinos ◽  
...  

2019 ◽  
Vol 4 (6) ◽  
pp. 234-238
Author(s):  
Yu. O. Ataman ◽  
◽  
A. V. Zharkova ◽  
Yu. S. Dudko ◽  
A. A. Roshchupkin

10.2741/2681 ◽  
2008 ◽  
Vol 13 (13) ◽  
pp. 312 ◽  
Author(s):  
Daniele Catalucci

2016 ◽  
Vol 23 (19) ◽  
pp. 1965-1980 ◽  
Author(s):  
Branislav Rovcanin ◽  
Branislava Medic ◽  
Gordana Kocic ◽  
Tatjana Cebovic ◽  
Marko Ristic ◽  
...  

Impact ◽  
2018 ◽  
Vol 2018 (3) ◽  
pp. 89-91
Author(s):  
Shin-ichi Tate

The field of molecular biology has provided great insights into the structure and function of key molecules. Thanks to this area of research, we can now grasp the biological details of DNA and have characterised an enormous number of molecules in massive data bases. These 'biological periodic tables' have allowed scientists to connect molecules to particular cellular events, furthering scientific understanding of biological processes. However, molecular biology has yet to answer questions regarding 'higher-order' molecular architecture, such as that of chromatin. Chromatin is the molecular material that serves as the building block for chromosomes, the structures that carry an organism's genetic information inside of the cell's nucleus. Understanding the physical properties of chromatin is crucial in developing a more thorough picture of how chromatin's structure relate to its key cellular functions. Moreover, by establishing a physical model of chromatin, scientists will be able to open the doors into the true inner workings of the cell nucleus. Professor Shin-ichi Tate and his team of researchers at Hiroshima University's Research Center for the Mathematics on Chromatin Live Dynamics (RcMcD), are attempting to do just that. Through a five-year grant funded by the Platform for Dynamic Approaches to Living Systems from the Ministry of Education, Culture, Sports, Science and Technology, Tate is aiming to gain a clearer understanding of the structure and dynamics of chromatin.


2019 ◽  
Vol 12 (12) ◽  
pp. e225879 ◽  
Author(s):  
Warner Mbuila Mampuya ◽  
Jonathan Dumont ◽  
Francois Lamontagne

In the perioperative setting, norepinephrine is used to increase blood pressure, an effect mediated mostly via arterial and venous vasoconstriction. Thus, norepinephrine is, allegedly, less likely to cause or worsen left ventricular outflow tract obstruction (LVOTO) than other inotropes. We report a case of norepinephrine-associated dynamic LVOTO and systolic anterior movement in a predisposed patient. This report highlights that unrecognised dynamic LVOTO may worsen shock parameters in patients treated with norepinephrine who have underlying myocardial hypertrophy.


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