Effect of Protein Cross-Linking on Excitable and Non-Excitable Membranes

1985 ◽  
pp. 367-375
Author(s):  
Doru-Georg Mărgineanu
Keyword(s):  
Cross Linking ◽  
Excitable Membranes ◽  
Protein Cross Linking

Transglutaminases: Protein Cross-Linking Enzymes in Tissues and Body Fluids

1994 ◽  
Vol 71 (04) ◽  
pp. 402-415 ◽  
Author(s):  
Daniel Aeschlimann ◽  
Mats Paulsson
Keyword(s):  
Body Fluids ◽  
Cross Linking ◽  
Protein Cross Linking

Tridegin, a Novel Peptidic Inhibitor of Factor XIIIa from the Leech, Haementeria ghilianii, Enhances Fibrinolysis In Vitro

1997 ◽  
Vol 77 (05) ◽  
pp. 0959-0963 ◽  
Author(s):  
Lisa Seale ◽  
Sarah Finney ◽  
Roy T Sawyer ◽  
Robert B Wallis
Keyword(s):  
Potent Inhibitor ◽  
Platelet Rich Plasma ◽  
Factor Xiiia ◽  
Cross Linking ◽  
Fibrinolytic Enzymes ◽  
Small Polypeptide ◽  
Tissue Plasminogen ◽  
Protein Cross Linking

SummaryTridegin is a potent inhibitor of factor Xllla from the leech, Haementeria ghilianii, which inhibits protein cross-linking. It modifies plasmin-mediated fibrin degradation as shown by the absence of D-dimer and approximately halves the time for fibrinolysis. Plasma clots formed in the presence of Tridegin lyse more rapidly when either streptokinase, tissue plasminogen activator or hementin is added 2 h after clot formation. The effect of Tridegin is markedly increased if clots are formed from platelet-rich plasma. Platelet-rich plasma clots are lysed much more slowly by the fibrinolytic enzymes used and if Tridegin is present, the rate of lysis returns almost to that of platelet- free clots. These studies indicate the important role of platelets in conferring resistance to commonly used fibrinolytic enzymes and suggest that protein cross-linking is an important step in this effect. Moreover they indicate that Tridegin, a small polypeptide, may have potential as an adjunct to thrombolytic therapy.

scholarly journals Glycan-protein cross-linking mass spectrometry reveals sialic acid-mediated protein networks on cell surfaces

2021 ◽  
Author(s):  
Yixuan Xie ◽  
Siyu Chen ◽  
Qiongyu Li ◽  
Ying Sheng ◽  
Michael R Alvarez ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Sialic Acid ◽  
Membrane Proteins ◽  
Cell Membranes ◽  
Sialic Acids ◽  
Cross Linking ◽  
Protein Networks ◽  
Cell Surfaces ◽  
Protein Cross Linking

A cross-linking method is developed to elucidate the glycan-mediated interactions between membrane proteins through sialic acids. The method provides previously unknown extensive glycomic interactions on cell membranes. The vast majority...

Effect of protein cross-linking aldehydes on nerve activity

1981 ◽  
Vol 89 (2) ◽  
pp. 159-165 ◽  
Author(s):  
D. G. Margineanu ◽  
Eva Katona ◽  
Junona Popa
Keyword(s):  
Cross Linking ◽  
Nerve Activity ◽  
Protein Cross Linking

A Novel Protein Cross-Linking Reaction in Stressed Neutral Protamine Hagedorn Formulations of Insulin

1999 ◽  
Vol 88 (3) ◽  
pp. 331-336 ◽  
Author(s):  
Ronald C. Beavis ◽  
Michael D. Kneirman ◽  
David Sharknas ◽  
Mark A. Heady ◽  
Bruce H. Frank ◽  
...  
Keyword(s):  
Cross Linking ◽  
Neutral Protamine Hagedorn ◽  
Novel Protein ◽  
Protein Cross Linking

scholarly journals Model of the Mediator middle module based on protein cross-linking

2013 ◽  
Vol 41 (20) ◽  
pp. 9266-9273 ◽  
Author(s):  
Laurent Larivière ◽  
Clemens Plaschka ◽  
Martin Seizl ◽  
Evgeniy V. Petrotchenko ◽  
Larissa Wenzeck ◽  
...  
Keyword(s):  
Cross Linking ◽  
Protein Cross Linking

scholarly journals Use of protein cross-linking and radiolytic footprinting to elucidate PsbP and PsbQ interactions within higher plant Photosystem II

2014 ◽  
Vol 111 (45) ◽  
pp. 16178-16183 ◽  
Author(s):  
Manjula P. Mummadisetti ◽  
Laurie K. Frankel ◽  
Henry D. Bellamy ◽  
Larry Sallans ◽  
Jost S. Goettert ◽  
...  
Keyword(s):  
Photosystem Ii ◽  
Cross Linking ◽  
Higher Plant ◽  
Protein Cross Linking

scholarly journals CLMSVault: A Software Suite for Protein Cross-Linking Mass-Spectrometry Data Analysis and Visualization

2017 ◽  
Vol 16 (7) ◽  
pp. 2645-2652 ◽  
Author(s):  
Mathieu Courcelles ◽  
Jasmin Coulombe-Huntington ◽  
Émilie Cossette ◽  
Anne-Claude Gingras ◽  
Pierre Thibault ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Data Analysis ◽  
Mass Spectrometry Data ◽  
Cross Linking ◽  
Software Suite ◽  
Protein Cross Linking

Control of a Tyrosyl Radical Mediated Protein Cross-Linking Reaction by Electrostatic Interaction

2012 ◽  
Vol 23 (8) ◽  
pp. 1600-1609 ◽  
Author(s):  
Kosuke Minamihata ◽  
Masahiro Goto ◽  
Noriho Kamiya
Keyword(s):  
Electrostatic Interaction ◽  
Cross Linking ◽  
Tyrosyl Radical ◽  
Protein Cross Linking
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