scholarly journals Glycan-protein cross-linking mass spectrometry reveals sialic acid-mediated protein networks on cell surfaces

2021 ◽  
Author(s):  
Yixuan Xie ◽  
Siyu Chen ◽  
Qiongyu Li ◽  
Ying Sheng ◽  
Michael R Alvarez ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Sialic Acid ◽  
Membrane Proteins ◽  
Cell Membranes ◽  
Sialic Acids ◽  
Cross Linking ◽  
Protein Networks ◽  
Cell Surfaces ◽  
Protein Cross Linking

A cross-linking method is developed to elucidate the glycan-mediated interactions between membrane proteins through sialic acids. The method provides previously unknown extensive glycomic interactions on cell membranes. The vast majority...

scholarly journals CLMSVault: A Software Suite for Protein Cross-Linking Mass-Spectrometry Data Analysis and Visualization

2017 ◽  
Vol 16 (7) ◽  
pp. 2645-2652 ◽  
Author(s):  
Mathieu Courcelles ◽  
Jasmin Coulombe-Huntington ◽  
Émilie Cossette ◽  
Anne-Claude Gingras ◽  
Pierre Thibault ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Data Analysis ◽  
Mass Spectrometry Data ◽  
Cross Linking ◽  
Software Suite ◽  
Protein Cross Linking

Boronic acid recognition based-gold nanoparticle-labeling strategy for the assay of sialic acid expression on cancer cell surface by inductively coupled plasma mass spectrometry

The Analyst ◽  
2016 ◽  
Vol 141 (4) ◽  
pp. 1286-1293 ◽  
Author(s):  
Xing Zhang ◽  
Beibei Chen ◽  
Man He ◽  
Yuan Zhang ◽  
Lu Peng ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Sialic Acid ◽  
Cell Surface ◽  
Cancer Cell ◽  
Boronic Acid ◽  
Inductively Coupled Plasma ◽  
Normal Cell ◽  
Sialic Acids ◽  
Inductively Coupled ◽  
Plasma Mass Spectrometry

Sialic acids are special sugars widely expressed at the termini of glycan chains on the cell surface, and their expression level on the cancer cell surface is much higher than on the normal cell surface.

scholarly journals Differential Tandem Mass Spectrometry-Based Cross-Linker: A New Approach for High Confidence in Identifying Protein Cross-Linking

2016 ◽  
Vol 88 (20) ◽  
pp. 10215-10222 ◽  
Author(s):  
Jayanta K. Chakrabarty ◽  
Aishwarya G. Naik ◽  
Michael B. Fessler ◽  
Gerhard R. Munske ◽  
Saiful M. Chowdhury
Keyword(s):  
Mass Spectrometry ◽  
Tandem Mass Spectrometry ◽  
Cross Linking ◽  
Tandem Mass ◽  
High Confidence ◽  
New Approach ◽  
Cross Linker ◽  
Protein Cross Linking

Linkage-selective derivatization for glycosylation site- and glycoform-specific characterization of sialic acid isomers by mass spectrometry

2021 ◽  
Author(s):  
Ye Peng ◽  
Bing Gu ◽  
Zhenyu Sun ◽  
Yueyue Li ◽  
Ying Zhang ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Sialic Acid ◽  
Sialic Acids ◽  
Glycosylation Site ◽  
Relative Quantification ◽  
Specific Manner ◽  
A Site

Here, we developed a linkage-selective derivatization approach for differentiation and relative quantification of α-2,3- and α-2,6-linked sialic acids in a site- and glycoform-specific manner. Linkage-selective derivatization with isotope molecules discriminates...

Pro-CrossLink. Software Tool for Protein Cross-Linking and Mass Spectrometry

2006 ◽  
Vol 78 (7) ◽  
pp. 2145-2149 ◽  
Author(s):  
Qiuxia Gao ◽  
Song Xue ◽  
Catalin E. Doneanu ◽  
Scott A. Shaffer ◽  
David R. Goodlett ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Software Tool ◽  
Cross Linking ◽  
Protein Cross Linking

scholarly journals Protein Cross-Linking Analysis Using Mass Spectrometry, Isotope-Coded Cross-Linkers, and Integrated Computational Data Processing

2006 ◽  
Vol 5 (9) ◽  
pp. 2270-2282 ◽  
Author(s):  
Jan Seebacher ◽  
Parag Mallick ◽  
Ning Zhang ◽  
James S. Eddes ◽  
Ruedi Aebersold ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Data Processing ◽  
Cross Linking ◽  
Computational Data ◽  
Protein Cross Linking

scholarly journals Mass Spectrometry Evidence for Cisplatin As a Protein Cross-Linking Reagent

2011 ◽  
Vol 83 (13) ◽  
pp. 5369-5376 ◽  
Author(s):  
Huilin Li ◽  
Yao Zhao ◽  
Hazel I. A. Phillips ◽  
Yulin Qi ◽  
Tzu-Yung Lin ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Cross Linking ◽  
Protein Cross Linking

scholarly journals Mass Spectrometry Based Proteomics Study of Cisplatin-Induced DNA–Protein Cross-Linking in Human Fibrosarcoma (HT1080) Cells

2017 ◽  
Vol 30 (4) ◽  
pp. 980-995 ◽  
Author(s):  
Xun Ming ◽  
Arnold Groehler ◽  
Erin D. Michaelson-Richie ◽  
Peter W. Villalta ◽  
Colin Campbell ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Cross Linking ◽  
Proteomics Study ◽  
Ht1080 Cells ◽  
Protein Cross Linking
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