History of Ductal Carcinoma In Situ Management Based Upon Data from Prospective, Randomized Clinical Trials

Author(s):  
Lisa A. Newman ◽  
Jessica M. Bensenhaver
2019 ◽  
Vol 26 (2) ◽  
pp. 665-671 ◽  
Author(s):  
Gábor Cserni ◽  
Anita Sejben

AbstractDuctal carcinoma in situ of the breast is a non-obligate precursor of invasive breast cancer, and at its lower risk end might not need treatment, a hypothesis tested in several currently running randomized clinical trials. This review describes the heterogeneity of grading ductal carcinoma in situ (DCIS). First it considers differences between low and high grade DCIS, and then it looks at several grading schemes and highlights how different these are, not only in the features considered for defining a given grade but also in their wording of a given variable seen in the grade in question. Rather than being fully comprehensive, the review aims to illustrate the inconsistencies. Reproducibility studies on grading mostly suggestive of moderate agreement on DCIS differentiation are also illustrated. The need for a well structured, more uniform and widely accepted language for grading DCIS is urged to avoid misunderstanding based misclassifications and improper treatment selection.


2020 ◽  
Vol 22 (1) ◽  
Author(s):  
Sarocha Chootipongchaivat ◽  
Nicolien T. van Ravesteyn ◽  
Xiaoxue Li ◽  
Hui Huang ◽  
Harald Weedon-Fekjær ◽  
...  

2018 ◽  
Vol 6 ◽  
pp. 2050313X1878172
Author(s):  
Florian Reinhardt ◽  
Britta Mathys ◽  
Petra Reinecke ◽  
Hans Neubauer ◽  
Tanja Fehm ◽  
...  

Ductal carcinoma in situ in men is incredibly rare and detection by conventional mammography and ultrasound is often challenging. We report an unusual case of a 50-year-old male, with no family history of breast cancer, who presented with an 8-year history of left-sided breast pain and recurrent bloody nipple discharge without any significant suspicious imaging features in mammography and targeted high-resolution ultrasound. Breast magnetic resonance imaging was performed as an adjunct modality. Magnetic resonance imaging findings revealed a suspicious retroareolar non-mass abnormality of segmental, linear and dendritic pattern, which was highly suspicious for a ductal carcinoma in situ. Stereotactic guided biopsy and subsequent mastectomy were consistent with pure high-grade ductal carcinoma in situ of the left breast. Overall, this case highlights the challenges in diagnosing ductal carcinoma in situ in men and demonstrates the importance for further investigating clinical suspicions of the male breast.


2005 ◽  
Vol 97 (2) ◽  
pp. 135-144 ◽  
Author(s):  
Bircan Erbas ◽  
Elena Provenzano ◽  
Jane Armes ◽  
Dorota Gertig

2007 ◽  
Vol 77 (1-2) ◽  
pp. 64-68 ◽  
Author(s):  
Astrid Cuncins-Hearn ◽  
Margaret Boult ◽  
Wendy Babidge ◽  
Helen Zorbas ◽  
Elmer Villanueva ◽  
...  

2014 ◽  
Vol 28 (5) ◽  
pp. 662-669 ◽  
Author(s):  
Melinda E Sanders ◽  
Peggy A Schuyler ◽  
Jean F Simpson ◽  
David L Page ◽  
William D Dupont

Author(s):  
Jean L. Wright ◽  
Habib Rahbar ◽  
Samilia Obeng-Gyasi ◽  
Ruth Carlos ◽  
Judy Tjoe ◽  
...  

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