A Short History of Obstructive Sleep Apnea Syndrome

2015 ◽  
pp. 357-363
Author(s):  
Brendon Richard Peters ◽  
Christian Guilleminault
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Obstructive Sleep Apnea Syndrome ◽  
Sleep Apnea Syndrome ◽  
Short History ◽  
Obstructive Sleep ◽  
History Of ◽  
Apnea Syndrome

scholarly journals The Relation between Pregnancy-Associated Plasma Protein A and Obstructive Sleep Apnea Syndrome

2018 ◽  
Vol 2018 ◽  
pp. 1-6 ◽  
Author(s):  
Ali Cengiz ◽  
Suat Konuk ◽  
Tuncer Tuğ
Keyword(s):  
Obstructive Sleep Apnea ◽  
Statistical Analysis ◽  
Sleep Apnea ◽  
Obstructive Sleep Apnea Syndrome ◽  
Plasma Protein ◽  
Sleep Apnea Syndrome ◽  
Protein A ◽  
Obstructive Sleep ◽  
History Of ◽  
Apnea Syndrome

Aim. We aimed to investigate the relationship between serum pregnancy-associated plasma protein A (PAPP-A) levels and obstructive sleep apnea syndrome (OSAS). Materials and Method. 44 patients with OSAS and 44 healthy adults were included in this study. The participants having rheumatic or systemic inflammatory disease, advanced liver or kidney failure, diabetes, heart failure, hypertension, pregnancy, prerenal azotemia, known history of coronary artery disease, any pulmonary disease, rhinitis, or atopy, history of major trauma or surgery within the last six 6 months, and inhaled nasal or systemic corticosteroid use or other anti-inflammatory medications and those with <18 years of age were excluded. Serum PAPP-A levels were determined by the Elisa method with the immune sandwich measuring method. Statistical analysis of the study was performed with SPSS 17.0 statistical analysis package program, and p<0.05 was considered as significant. Results. Serum PAPP-A levels of patients with OSAS (2.350 ng/ml (0.641–4.796)) were significantly higher (p<0.001) when compared with healthy controls (0.971 ng/ml (0.109–2.679)). There was a statistically significant difference in serum PAPP-A levels between groups of OSAS patients according to the classification of OSAS severity. Between the groups of patients with OSAS, serum levels of PAPP-A in moderate group was significantly higher when compared with severe OSAS group (p<0.001). There was positive correlations between PAPP-A levels and night minimum (p=0.042,  r=0.309), and average oxygen levels (p=0.006,  r=0.407). There was a negative correlation between PAPP-A levels and AHI (p=0.002,  r=−0.460). Conclusion. Higher PAPP-A levels in OSAS patients that were found in this study show inflammatory component in OSAS.

scholarly journals 0910 Prevalence And Risk Factors Of Obstructive Sleep Apnea Syndrome In 3-14 Yearsold Children In Beijing: A Cross-sectional Surveyabstract

SLEEP ◽  
2020 ◽  
Vol 43 (Supplement_1) ◽  
pp. A346-A346
Author(s):  
W Wei
Keyword(s):  
Risk Factors ◽  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Obstructive Sleep Apnea Syndrome ◽  
Sleep Apnea Syndrome ◽  
Cross Sectional ◽  
Obstructive Sleep ◽  
Positive Rate ◽  
History Of ◽  
Apnea Syndrome

Abstract Introduction To explore the prevalence and risk factors of obstructive sleep apnea syndrome (OSAS) in 3-14 years old children in Beijing. Methods A cross-sectional study of random stratified cluster sampling was conducted on 3-14 years old children and adolescents in Beijing. The preliminary screening was completed through Pediatric Sleep Questionnaire (PSQ) investigation and the diagnosis of OSAS was conducted by polysomnography. Results After random sampling, a total of 11 kindergartens, 7 primary schools and 8 junior high schools from 7 districts of Beijing were involved in the survey. A total of 11420 questionnaires were sent out, and 10743 (94.07%) were recovered. The final effective data were 9198 (effective response rate 85.62%). The age of the investigated children was 8.8±3.8 years. PSQ positive rate was 8.86% (95CI 8.28-9.44%). With diagnostic criteria AHI≥5, the estimated prevalence of OSAS in Beijing children was 5.90% (95%CI 3.72-8.28%); with ICSD-3 diagnostic criteria (OAHI&gt;1), the estimated prevalence was 8.08% (95% CI 5.74-10.62%). Overweight (OR=3.13), frequent allergic rhinitis (OR=6.80) and family snoring history (OR=6.14) were important risk factors for children’s OSAS. Conclusion PSQ was used in Beijing children’s OSAS epidemiological survey with good reliability and validity. The positive rate of the PSQ screening was 8.86% (95CI 8.28-9.44%);the estimated prevalence of OSAS in children aged 3-14 years in Beijing was 5.90% (95%CI 3.72-8.28%) with criteria AHI≥5 and 8.08% (95%CI 5.74-10.62%) with criteria OAHI&gt;1, respectively. Gender, BMI, history of ENT and family history of snoring were important risk factors for children’s OSAS. Support This work was supported by Beijing Municipal Science and Technology Project grant (Z161100000116050 and Z161100003216212) and Beijing Municipal Administration of Hospitals Clinical Technology Innovation Project grant (XMLX201701).

Epidemiology and Natural History of Obstructive Sleep Apnea Syndrome

1991 ◽  
pp. 84-91 ◽  
Author(s):  
F. Cirignotta ◽  
G. Coccagna ◽  
M. Partinen ◽  
R. D’Alessandro ◽  
E. Lugaresi
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Natural History ◽  
Obstructive Sleep Apnea Syndrome ◽  
Sleep Apnea Syndrome ◽  
Obstructive Sleep ◽  
History Of ◽  
Apnea Syndrome

Postoperative monitoring of children with obstructive sleep apnea syndrome

2014 ◽  
Vol 155 (18) ◽  
pp. 703-707 ◽  
Author(s):  
Pálma Benedek ◽  
Gabriella Kiss ◽  
Eszter Csábi ◽  
Gábor Katona
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Obstructive Sleep Apnea Syndrome ◽  
Preoperative Evaluation ◽  
Sleep Apnea Syndrome ◽  
Study Patient ◽  
Severe Obstructive Sleep Apnea ◽  
Obstructive Sleep ◽  
Significant Difference ◽  
Apnea Syndrome

Introduction: Treatment of pediatric obstructive sleep apnea syndrome is surgical. The incidence of postoperative respiratory complications in this population is 5–25%. Aim: The aim of the authors was to present the preoperative evaluation and monitoring procedure elaborated in Heim Pál Children Hospital, Budapest. Method: 142 patients were involved in the study. Patient history was obtained and physical examination was performed in all cases. Thereafter, polysomnography was carried out, the severity of the obstructive sleep apnea syndrome was determined, and the patients underwent tonsilloadenotomy. Results: 45 patients with mild, 50 patients with moderate and 47 patients with severe obstructive sleep apnea syndrome were diagnosed. There was no complication in patients with mild disease, while complications were observed in 6 patients in the moderate group and 24 patients in the severe group (desaturation, apnea, stridor, stop breathing) (p<0.000). In patients with severe obstructive sleep apnea syndrome, no significant difference was noted in preoperative apnoea-hypapnea index (p = 0.23) and in nadir oxygen saturation values (p = 0.73) between patients with and without complication. Conclusions: Patients with severe obstructive sleep apnea syndrome should be treated in hospital where pediatric intensive care unit is available. Orv. Hetil., 2014, 155(18), 703–707.

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