scholarly journals Pharmacokinetics and Pharmacodynamics in Breast Cancer Animal Models

2016 ◽  
pp. 271-287 ◽  
Author(s):  
Wei Wang ◽  
Subhasree Nag ◽  
Ruiwen Zhang
Keyword(s):  
Breast Cancer ◽  
Animal Models ◽  
Pharmacokinetics And Pharmacodynamics

scholarly journals New insights on CRISPR/Cas9-based therapy for breast Cancer

2021 ◽  
Vol 43 (1) ◽  
Author(s):  
Hussein Sabit ◽  
Shaimaa Abdel-Ghany ◽  
Huseyin Tombuloglu ◽  
Emre Cevik ◽  
Amany Alqosaibi ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Research ◽  
Animal Models ◽  
Human Cancer ◽  
Step Process ◽  
Cancer Initiation ◽  
Malignant State ◽  
Treat Breast Cancer

AbstractCRISPR/Cas9 has revolutionized genome-editing techniques in various biological fields including human cancer research. Cancer is a multi-step process that encompasses the accumulation of mutations that result in the hallmark of the malignant state. The goal of cancer research is to identify these mutations and correlate them with the underlying tumorigenic process. Using CRISPR/Cas9 tool, specific mutations responsible for cancer initiation and/or progression could be corrected at least in animal models as a first step towards translational applications. In the present article, we review various novel strategies that employed CRISPR/Cas9 to treat breast cancer in both in vitro and in vivo systems.

scholarly journals G1T48, an oral selective estrogen receptor degrader, and the CDK4/6 inhibitor lerociclib inhibit tumor growth in animal models of endocrine-resistant breast cancer

2020 ◽  
Vol 180 (3) ◽  
pp. 635-646 ◽  
Author(s):  
Kaitlyn J. Andreano ◽  
Suzanne E. Wardell ◽  
Jennifer G. Baker ◽  
Taylor K. Desautels ◽  
Robert Baldi ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Estrogen Receptor ◽  
Animal Models ◽  
Tumor Growth ◽  
Inhibit Tumor Growth

scholarly journals Automated computer quantification of breast cancer in small-animal models using PET-guided MR image co-segmentation

2013 ◽  
Vol 3 (1) ◽  
pp. 49 ◽  
Author(s):  
Ulas Bagci ◽  
Gabriela Kramer-Marek ◽  
Daniel J Mollura
Keyword(s):  
Breast Cancer ◽  
Animal Models ◽  
Small Animal ◽  
Mr Image ◽  
Small Animal Models

Prolactin Receptors in Normal Tissues and in Animal Models for Breast Cancer

2020 ◽  
pp. 61-94
Author(s):  
Paul A. Kelly ◽  
David Gould ◽  
Hiroaki Okamura ◽  
Jean Dijane
Keyword(s):  
Breast Cancer ◽  
Animal Models ◽  
Prolactin Receptors ◽  
Normal Tissues

scholarly journals Models of breast cancer: is merging human and animal models the future?

2003 ◽  
Vol 6 (1) ◽  
Author(s):  
Jong B Kim ◽  
Michael J O'Hare ◽  
Robert Stein
Keyword(s):  
Breast Cancer ◽  
Animal Models ◽  
The Future

Abstract 4245: BLZ-100 provides optical contrast in animal models of breast cancer

2016 ◽  
Author(s):  
Stacey Hansen ◽  
Janean Fidel ◽  
Katie Kennedy ◽  
William Dernell ◽  
Boel Fransson ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Animal Models ◽  
Optical Contrast
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