Functional Tooth Regeneration

2017 ◽  
pp. 97-116 ◽  
Author(s):  
Masamitsu Oshima ◽  
Miho Ogawa ◽  
Takashi Tsuji
Keyword(s):  
Tooth Regeneration ◽  
Functional Tooth

Functional Tooth Regeneration

2017 ◽  
pp. 73-95
Author(s):  
Masamitsu Oshima ◽  
Takashi Tsuji
Keyword(s):  
Tooth Regeneration ◽  
Functional Tooth

scholarly journals Mesenchymal Stem Cell-Mediated Functional Tooth Regeneration in Swine

PLoS ONE ◽  
2006 ◽  
Vol 1 (1) ◽  
pp. e79 ◽  
Author(s):  
Wataru Sonoyama ◽  
Yi Liu ◽  
Dianji Fang ◽  
Takayoshi Yamaza ◽  
Byoung-Moo Seo ◽  
...  
Keyword(s):  
Stem Cell ◽  
Mesenchymal Stem Cell ◽  
Tooth Regeneration ◽  
Functional Tooth

scholarly journals Tooth Regeneration: Turning Hopes into Realities

2020 ◽  
Vol 7 (3) ◽  
pp. 30-34
Author(s):  
Kriti Garg ◽  
Silky Mehta ◽  
C. V. Sruthi Vyaasini ◽  
Bhavika Sindhu ◽  
Sheenam Kansal ◽  
...  
Keyword(s):  
Stem Cells ◽  
Growth Factors ◽  
Adult Stem Cells ◽  
Therapeutic Strategy ◽  
Tooth Regeneration ◽  
Developmental Programs ◽  
Functional Tooth ◽  
Significant Effort ◽  
Made In

Functional tooth regeneration has shown promising therapeutic strategy. Tooth regeneration is possible by combine use of adult stem cells, growth factors, and scaffold. In recent years, researchers have explored tooth regeneration. Significant effort has been made in recent decades to identify and characterize tooth stem cells and to unravel the developmental programs which these cells follow to generate a tooth.

scholarly journals Functional Tooth Regeneration Using a Bioengineered Tooth Unit as a Mature Organ Replacement Regenerative Therapy

PLoS ONE ◽  
2011 ◽  
Vol 6 (7) ◽  
pp. e21531 ◽  
Author(s):  
Masamitsu Oshima ◽  
Mitsumasa Mizuno ◽  
Aya Imamura ◽  
Miho Ogawa ◽  
Masato Yasukawa ◽  
...  
Keyword(s):  
Regenerative Therapy ◽  
Tooth Regeneration ◽  
Functional Tooth ◽  
Organ Replacement Regenerative Therapy ◽  
Bioengineered Tooth ◽  
Organ Replacement

scholarly journals Anti–USAG-1 therapy for tooth regeneration through enhanced BMP signaling

2021 ◽  
Vol 7 (7) ◽  
pp. eabf1798
Author(s):  
A. Murashima-Suginami ◽  
H. Kiso ◽  
Y. Tokita ◽  
E. Mihara ◽  
Y. Nambu ◽  
...  
Keyword(s):  
Tooth Development ◽  
Bmp Signaling ◽  
Tooth Agenesis ◽  
Tooth Regeneration ◽  
Missing Teeth ◽  
Morphogenetic Protein ◽  
Genetic Abnormalities ◽  
Direct Binding ◽  
Tooth Germs ◽  
Lipoprotein Receptor Related Protein

Uterine sensitization–associated gene-1 (USAG-1) deficiency leads to enhanced bone morphogenetic protein (BMP) signaling, leading to supernumerary teeth formation. Furthermore, antibodies interfering with binding of USAG-1 to BMP, but not lipoprotein receptor–related protein 5/6 (LRP5/6), accelerate tooth development. Since USAG-1 inhibits Wnt and BMP signals, the essential factors for tooth development, via direct binding to BMP and Wnt coreceptor LRP5/6, we hypothesized that USAG-1 plays key regulatory roles in suppressing tooth development. However, the involvement of USAG-1 in various types of congenital tooth agenesis remains unknown. Here, we show that blocking USAG-1 function through USAG-1 knockout or anti–USAG-1 antibody administration relieves congenital tooth agenesis caused by various genetic abnormalities in mice. Our results demonstrate that USAG-1 controls the number of teeth by inhibiting development of potential tooth germs in wild-type or mutant mice missing teeth. Anti–USAG-1 antibody administration is, therefore, a promising approach for tooth regeneration therapy.

Nanotechnology For Tooth Regeneration

2014 ◽  
Vol 5 (1) ◽  
pp. 32-37
Author(s):  
Waqar Ahmed ◽  
St John Crean
Keyword(s):  
Tooth Regeneration

scholarly journals A new dinosaur (Theropoda, Spinosauridae) from the Cretaceous (Cenomanian) Alcântara Formation, Cajual Island, Brazil

2011 ◽  
Vol 83 (1) ◽  
pp. 99-108 ◽  
Author(s):  
Alexander WA. Kellner ◽  
Sergio A.K. Azevedo ◽  
Elaine B. Machado ◽  
Luciana B. de Carvalho ◽  
Deise D.R. Henriques
Keyword(s):  
New Species ◽  
Late Cretaceous ◽  
North Africa ◽  
Anterior Part ◽  
Functional Tooth

A new spinosaurid taxon, Oxalaia quilombensis gen. et sp. nov., is described based on the anterior part of a snout and a fragment of a maxilla. These specimens were collected at the Laje do Coringa site, Late Cretaceous (Cenomanian) of the São Luis Basin. Unlike Cristatusaurus and Suchomimus, Oxalaia quilombensis lacks serrations on the teeth. The new species differs from Angaturama limai by having the anterior part of the premaxillae more expanded and by lacking a sagittal premaxillary crest. It further differs from Spinosaurus cf. S. aegyptiacus and the Algerian spinosaurid by the rounder shape of the terminal expansion. Furthermore, xalaia quilobensis has one functional tooth followed by two replacement teeth, a feature not previously observed in theropods. Oxalaia quilombensis appears to be more closely related to the spinosaurids found in North Africa than to the Brazilian members of this clade and thus further increases the diversity of these enigmatic predatory dinosaurs in this country.

scholarly journals Therapeutic potential of HERS spheroids in tooth regeneration

Theranostics ◽  
2020 ◽  
Vol 10 (16) ◽  
pp. 7409-7421
Author(s):  
Yufeng Duan ◽  
Xuebing Li ◽  
Sicheng Zhang ◽  
Shikai Wang ◽  
Tao Wang ◽  
...  
Keyword(s):  
Therapeutic Potential ◽  
Tooth Regeneration

scholarly journals Functional tooth restoration utilising split germs through re-regionalisation of the tooth-forming field

2015 ◽  
Vol 5 (1) ◽  
Author(s):  
Naomi Yamamoto ◽  
Masamitsu Oshima ◽  
Chie Tanaka ◽  
Miho Ogawa ◽  
Kei Nakajima ◽  
...  
Keyword(s):  
Functional Tooth
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