Ligand-Directed N-Sulfonyl Pyridone Chemistry for Selective Native Protein Labeling and Imaging in Live Cell

Author(s):  
Marie Masuda ◽  
Kazuya Matsuo ◽  
Itaru Hamachi
2018 ◽  
Vol 19 (12) ◽  
pp. 3778 ◽  
Author(s):  
Nina Bozhanova ◽  
Mikhail Baranov ◽  
Nadezhda Baleeva ◽  
Alexey Gavrikov ◽  
Alexander Mishin

Fluorogens are an attractive type of dye for imaging applications, eliminating time-consuming washout steps from staining protocols. With just a handful of reported fluorogen-protein pairs, mostly in the green region of spectra, there is a need for the expansion of their spectral range. Still, the origins of solvatochromic and fluorogenic properties of the chromophores suitable for live-cell imaging are poorly understood. Here we report on the synthesis and labeling applications of novel red-shifted fluorogenic cell-permeable green fluorescent protein (GFP) chromophore analogs.


2014 ◽  
Vol 136 (28) ◽  
pp. 9990-9998 ◽  
Author(s):  
Zhengqiu Li ◽  
Danyang Wang ◽  
Lin Li ◽  
Sijun Pan ◽  
Zhenkun Na ◽  
...  

Molecules ◽  
2016 ◽  
Vol 21 (9) ◽  
pp. 1163 ◽  
Author(s):  
Feng Gao ◽  
Tang Gao ◽  
Kechao Zhou ◽  
Wenbin Zeng

2009 ◽  
Vol 5 (5) ◽  
pp. 275-276 ◽  
Author(s):  
Qing Lin ◽  
Reyna K V Lim

ACS Omega ◽  
2018 ◽  
Vol 3 (2) ◽  
pp. 2104-2110 ◽  
Author(s):  
Karen A. Hecht ◽  
Yijia Xiong ◽  
Daniel A. Barrack ◽  
Nicole R. Ford ◽  
Guritno Roesijadi ◽  
...  

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