Assisted Reproduction and Male Factor Fertility: Which Type Is Right?

2010 ◽  
pp. 119-123
Author(s):  
James Goldfarb ◽  
Nina Desai
Keyword(s):  
Assisted Reproduction ◽  
Male Factor

scholarly journals The causes of infertility in women presenting to gynaecology clinics in Harare, Zimbabwe; a cross sectional study

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Mugove G. Madziyire ◽  
Thulani L. Magwali ◽  
Vasco Chikwasha ◽  
Tinovimba Mhlanga
Keyword(s):  
Assisted Reproduction ◽  
Cross Sectional Study ◽  
Male Factor ◽  
Cross Sectional ◽  
Unprotected Sexual Intercourse ◽  
Assisted Reproduction Techniques ◽  
Public Facilities ◽  
Tubal Blockage ◽  
Private And Public

Abstract Background Infertility affects 48.5 million couples globally. It is defined clinically as failure to conceive after 12 months or more of regular unprotected sexual intercourse. The contribution of various aetiological factors to infertility differs per population. The causes of infertility have not been assessed in Zimbabwe. Our objectives were to determine the reproductive characteristics, causes and outcomes of women presenting for infertility care. Methods A retrospective and prospective study of women who had not conceived within a year of having unprotected intercourse presenting in private and public facilities in Harare was done. A diagnosis was made based on the history, examination and results whenever these were deemed sufficient. Data was analysed using STATA SE/15. A total of 216 women were recruited. Results Of the 216 women recruited, two thirds (144) of them had primary infertility. The overall period of infertility ranged from 1 to 21 years with an average of 5.6 ± 4.7 years whilst 98 (45.4%) of the couples had experienced 2–4 years of infertility and 94 (43.5%) had experience 5 or more years of infertility. About 1 in 5 of the women had irregular menstrual cycles with 10 of them having experienced amenorrhoea of at least 1 year. Almost half of the participants (49%) were overweight or obese. The most common cause for infertility was ‘unexplained’ in 22% of the women followed by tubal blockage in 20%, male factor in 19% and anovulation in 16%. Of the 49 (22.7%) women who conceived 21(9.7%) had a live birth while 23 (10.7%) had an ongoing pregnancy at the end of follow up. Thirty-seven (17.1%) had Assisted Reproduction Techniques (ART) in the form of Invitro-fertilisation/Intracytoplasmic Sperm Injection (IVF/ICSI) or Intra-Uterine Insemination (IUI). Assisted Reproduction was significantly associated with conception. Conclusion Most women present when chances of natural spontaneous conception are considerably reduced. This study shows an almost equal contribution between tubal blockage, male factor and unexplained infertility. Almost half of the causes are female factors constituted by tubal blockage, anovulation and a mixture of the two. Improved access to ART will result in improved pregnancy rates. Programs should target comprehensive assessment of both partners and offer ART.

The effect of the 2004 Italian law on outcomes of assisted reproduction technology in severe male factor infertility

2010 ◽  
Vol 20 (1) ◽  
pp. 2-10 ◽  
Author(s):  
G.B. La Sala ◽  
A. Nicoli ◽  
F. Capodanno ◽  
I. Rondini ◽  
M.T. Villani ◽  
...  
Keyword(s):  
Assisted Reproduction ◽  
Male Factor Infertility ◽  
Male Factor ◽  
Assisted Reproduction Technology ◽  
Italian Law

scholarly journals Couples with mild male factor infertility and at least 3 failed previous IVF attempts may benefit from laparoscopic investigation regarding assisted reproduction outcome

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Agni Pantou ◽  
Konstantinos Sfakianoudis ◽  
Evangelos Maziotis ◽  
Polina Giannelou ◽  
Sokratis Grigoriadis ◽  
...  
Keyword(s):  
Assisted Reproduction ◽  
Male Factor Infertility ◽  
Male Factor

scholarly journals Human Sperm Cryopreservation: Update on Techniques, Effect on DNA Integrity, and Implications for ART

2012 ◽  
Vol 2012 ◽  
pp. 1-12 ◽  
Author(s):  
Marlea Di Santo ◽  
Nicoletta Tarozzi ◽  
Marco Nadalini ◽  
Andrea Borini
Keyword(s):  
Assisted Reproduction ◽  
Human Sperm ◽  
Sperm Chromatin ◽  
Dna Integrity ◽  
Sperm Cryopreservation ◽  
Male Factor ◽  
Assisted Reproduction Technologies ◽  
Chromatin Integrity ◽  
And Function ◽  
Thawing Procedure

Cryopreservation of human spermatozoa—introduced in the 1960's—has been recognized as an efficient procedure for management of male fertility before therapy for malignant diseases, vasectomy or surgical infertility treatments, to store donor and partner spermatozoa before assisted reproduction treatments and to ensure the recovery of a small number of spermatozoa in severe male factor infertility. Despite the usefulness of it, cryopreservation may lead to deleterious changes of sperm structure and function: while the effects of cryopreservation on cells are well documented, to date there is no agreement in the literature on whether or not cryopreservation affects sperm chromatin integrity or on the use of a unique and functional protocol for the freezing-thawing procedure. Therefore, sperm cryopreservation is an important component of fertility management and much of its successful application seems to affect the reproductive outcome of assisted reproduction technologies (ART): appropriate use of cryoprotectants before and sperm selection technologies after cryopreservation seem to have the greatest impact on preventing DNA fragmentation, thus improving sperm cryosurvival rates.

scholarly journals Rare Sperm Freezing

2021 ◽  
Author(s):  
Desislava Dyulgerova-Nikolova ◽  
Tanya Milachich
Keyword(s):  
Assisted Reproduction ◽  
Reproductive Technology ◽  
Sperm Cells ◽  
Obstructive Azoospermia ◽  
Sperm Cryopreservation ◽  
Male Factor ◽  
Male Gametes ◽  
Future Fertility ◽  
Fresh Semen ◽  
Sperm Freezing

Gamete cryobanking has been widely incorporated in present assisted reproductive technology (ART). Preserving male gametes for future fertility is considered to be an easy and accessible way to insure one’s reproduction. Despite the fact that the method could not secure success, sperm freezing could be the only chance to father biological offspring. In cases when severe male factor (SMF) infertility is diagnosed (retrograde ejaculation, virtual azoospermia, obstructive azoospermia, cryptozoospermia) and providing fresh semen samples for assisted reproduction may alter chances to achieve pregnancy, rare sperm cryopreservation could contribute for conceiving. Isolation, selection and cryopreservation of single sperm cells from semen samples is a challenging procedure. Different approaches and devices could be used in order to extract utmost spermatozoa. Aiming to highest cryosurvival rates sperm freezing protocols should be carefully considered. For some men, rare sperm cryopreservation might be the only alternative for parenting biological offspring. Thus, the latter technique should be widely discussed, developed and practiced in assisted reproduction.

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