Death and Survival Signals in Photodynamic Therapy

2010 ◽  
pp. 7-33 ◽  
Author(s):  
Michael Dewaele ◽  
Tom Verfaillie ◽  
Wim Martinet ◽  
Patrizia Agostinis
Keyword(s):  
Photodynamic Therapy ◽  
Survival Signals

Construction of a near-infrared responsive upconversion nanoplatform against hypoxic tumors via NO-enhanced photodynamic therapy

Nanoscale ◽  
2020 ◽  
Vol 12 (14) ◽  
pp. 7875-7887 ◽  
Author(s):  
Ying Lan ◽  
Xiaohui Zhu ◽  
Ming Tang ◽  
Yihan Wu ◽  
Jing Zhang ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Near Infrared ◽  
Upconversion Nanoparticles

A near-infrared (NIR) activated theranostic nanoplatform based on upconversion nanoparticles (UCNPs) is developed in order to overcome the hypoxia-associated resistance in photodynamic therapy by photo-release of NO upon NIR illumination.

Porphyrin-functionalized coordination star polymers and their potential applications in photodynamic therapy

2019 ◽  
Vol 10 (45) ◽  
pp. 6116-6121 ◽  
Author(s):  
Tan Ji ◽  
Lei Xia ◽  
Wei Zheng ◽  
Guang-Qiang Yin ◽  
Tao Yue ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Self Assembly ◽  
Star Polymers ◽  
New Family ◽  
Potential Applications

We present a new family of porphyrin-functionalized coordination star polymers prepared through combination of coordination-driven self-assembly and post-assembly polymerization. Their self-assembly behaviour in water and potential for photodynamic therapy were demonstrated.

A nitroreductase-activatable near-infrared theranostic photosensitizer for photodynamic therapy under mild hypoxia

2020 ◽  
Vol 56 (43) ◽  
pp. 5819-5822
Author(s):  
Jing Zheng ◽  
Yongzhuo Liu ◽  
Fengling Song ◽  
Long Jiao ◽  
Yingnan Wu ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Triplet State ◽  
Near Infrared ◽  
Mild Hypoxia

In this study, a near-infrared (NIR) theranostic photosensitizer was developed based on a heptamethine aminocyanine dye with a long-lived triplet state.

Dinuclear phosphorescent rhenium(i) complexes as potential anticancer and photodynamic therapy agents

2020 ◽  
Vol 49 (33) ◽  
pp. 11583-11590 ◽  
Author(s):  
Zheng-Yin Pan ◽  
Dai-Hong Cai ◽  
Liang He
Keyword(s):  
Photodynamic Therapy ◽  
Cell Apoptosis ◽  
Lysosomal Dysfunction ◽  
Intracellular Ros

Two dinuclear organometallic Re(i) complexes increase intracellular ROS levels, causing lysosomal dysfunction and cell apoptosis.

Involvement of CFTR in photodynamic therapy-mediated apoptosis

2010 ◽  
Vol 34 (8) ◽  
pp. S44-S44
Author(s):  
Juan Juan Chen ◽  
Xiao Hua Jiang ◽  
Hsiao Chang Chan
Keyword(s):  
Photodynamic Therapy

Apoptosis is induced by caspase activation and cytochrome c release in photodynamic therapy (PDT) of human hepatoteilular carcinoma cells

2001 ◽  
Vol 120 (5) ◽  
pp. A363-A363
Author(s):  
A OKUMURA ◽  
M HAMBLIN ◽  
T HASAN ◽  
T ISHIKAWA ◽  
S KAKUMU ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Cytochrome C ◽  
Carcinoma Cells ◽  
Caspase Activation ◽  
Cytochrome C Release

Hypericin is an encouraging new photosensitizer for photodynamic therapy of esophageal dysplasia/cancer: Antiproliferative and apoptotic effects

2001 ◽  
Vol 120 (5) ◽  
pp. A443-A443
Author(s):  
M LENZ ◽  
M HOEPFNER ◽  
A THEISS ◽  
B LAMPE ◽  
H KASHTAN ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Esophageal Dysplasia ◽  
Apoptotic Effects

Analysis of photosensitivity in Japanese cancer-bearing patients receiving photodynamic therapy with porfimer sodium (PhotofrinTM)

2001 ◽  
Vol 17 (5) ◽  
pp. 241-243 ◽  
Author(s):  
Shin-Ichi Moriwaki ◽  
Junko Misawa ◽  
Yasushi Yoshinari ◽  
Ichiro Yamada ◽  
Masahiro Takigawa ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Porfimer Sodium
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