Idiopathic Pulmonary Fibrosis: The Epidemiology and Natural History of Disease

2013 ◽  
pp. 9-34 ◽  
Author(s):  
Olga Tourin ◽  
Jeffrey J. Swigris ◽  
Amy L. Olson
Keyword(s):  
Natural History ◽  
Idiopathic Pulmonary Fibrosis ◽  
Pulmonary Fibrosis ◽  
History Of Disease ◽  
History Of

scholarly journals S19 The impact of clotting abnormalities on the natural history of idiopathic pulmonary fibrosis: an extended follow up of a population based cohort

Thorax ◽  
2016 ◽  
Vol 71 (Suppl 3) ◽  
pp. A13.1-A13
Author(s):  
V Navaratnam ◽  
AW Fogarty ◽  
T McKeever ◽  
N Thompson ◽  
G Jenkins ◽  
...  
Keyword(s):  
Natural History ◽  
Idiopathic Pulmonary Fibrosis ◽  
Pulmonary Fibrosis ◽  
Population Based ◽  
History Of ◽  
The Impact

Natural history of honeycombing: follow-up of patients with idiopathic pulmonary fibrosis treated with single-lung transplantation

2012 ◽  
Vol 118 (1) ◽  
pp. 40-50 ◽  
Author(s):  
G. Mineo ◽  
F. Ciccarese ◽  
D. Attinà ◽  
V. Di Scioscio ◽  
N. Sciascia ◽  
...  
Keyword(s):  
Natural History ◽  
Idiopathic Pulmonary Fibrosis ◽  
Pulmonary Fibrosis ◽  
Lung Transplantation ◽  
Single Lung Transplantation ◽  
History Of

Interactions between Cigarette Smoking and the Natural History of Idiopathic Pulmonary Fibrosis

CHEST Journal ◽  
1990 ◽  
Vol 98 (1) ◽  
pp. 71-76 ◽  
Author(s):  
Hubert De Cremoux ◽  
Jean-François Bernaudin ◽  
Philippe Laurent ◽  
Patrick Brochard ◽  
Jean Bignon
Keyword(s):  
Natural History ◽  
Idiopathic Pulmonary Fibrosis ◽  
Pulmonary Fibrosis ◽  
Cigarette Smoking ◽  
History Of

scholarly journals Role of atmospheric pollution on the natural history of idiopathic pulmonary fibrosis

Thorax ◽  
2017 ◽  
Vol 73 (2) ◽  
pp. 145-150 ◽  
Author(s):  
Lucile Sesé ◽  
Hilario Nunes ◽  
Vincent Cottin ◽  
Shreosi Sanyal ◽  
Morgane Didier ◽  
...  
Keyword(s):  
Air Pollution ◽  
Natural History ◽  
Idiopathic Pulmonary Fibrosis ◽  
Pulmonary Fibrosis ◽  
Disease Progression ◽  
Air Pollutant ◽  
Rapid Decline ◽  
History Of ◽  
The Impact

IntroductionIdiopathic pulmonary fibrosis (IPF) has an unpredictable course corresponding to various profiles: stability, physiological disease progression and rapid decline. A minority of patients experience acute exacerbations (AEs). A recent study suggested that ozone and nitrogen dioxide might contribute to the occurrence of AE. We hypothesised that outdoor air pollution might influence the natural history of IPF.MethodsPatients were selected from the French cohort COhorte FIbrose (COFI), a national multicentre longitudinal prospective cohort of IPF (n=192). Air pollutant levels were assigned to each patient from the air quality monitoring station closest to the patient’s geocoded residence. Cox proportional hazards model was used to evaluate the impact of air pollution on AE, disease progression and death.ResultsOnset of AEs was significantly associated with an increased mean level of ozone in the six preceding weeks, with an HR of 1.47 (95% CI 1.13 to 1.92) per 10 µg/m3 (p=0.005). Cumulative levels of exposure to particulate matter PM10 and PM2.5 were above WHO recommendations in 34% and 100% of patients, respectively. Mortality was significantly associated with increased levels of exposure to PM10 (HR=2.01, 95% CI 1.07 to 3.77) per 10 µg/m3 (p=0.03), and PM2.5 (HR=7.93, 95% CI 2.93 to 21.33) per 10 µg/m3 (p<0.001).ConclusionThis study suggests that air pollution has a negative impact on IPF outcomes, corroborating the role of ozone on AEs and establishing, for the first time, the potential role of long-term exposure to PM10 and PM2.5 on overall mortality.

The natural history of idiopathic pulmonary fibrosis in a large European population: the role of age, sex and comorbidities

2021 ◽  
Author(s):  
Antonella Caminati ◽  
Fabiana Madotto ◽  
Sara Conti ◽  
Giancarlo Cesana ◽  
Lorenzo Mantovani ◽  
...  
Keyword(s):  
Natural History ◽  
Idiopathic Pulmonary Fibrosis ◽  
Pulmonary Fibrosis ◽  
European Population ◽  
History Of

scholarly journals Natural history of idiopathic pulmonary fibrosis

2015 ◽  
Vol 109 (6) ◽  
pp. 661-670 ◽  
Author(s):  
Hyun Joo Kim ◽  
David Perlman ◽  
Rade Tomic
Keyword(s):  
Natural History ◽  
Idiopathic Pulmonary Fibrosis ◽  
Pulmonary Fibrosis ◽  
History Of
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