Natural history of honeycombing: follow-up of patients with idiopathic pulmonary fibrosis treated with single-lung transplantation

2012 ◽  
Vol 118 (1) ◽  
pp. 40-50 ◽  
Author(s):  
G. Mineo ◽  
F. Ciccarese ◽  
D. Attinà ◽  
V. Di Scioscio ◽  
N. Sciascia ◽  
...  
Keyword(s):  
Natural History ◽  
Idiopathic Pulmonary Fibrosis ◽  
Pulmonary Fibrosis ◽  
Lung Transplantation ◽  
Single Lung Transplantation ◽  
History Of

scholarly journals S19 The impact of clotting abnormalities on the natural history of idiopathic pulmonary fibrosis: an extended follow up of a population based cohort

Thorax ◽  
2016 ◽  
Vol 71 (Suppl 3) ◽  
pp. A13.1-A13
Author(s):  
V Navaratnam ◽  
AW Fogarty ◽  
T McKeever ◽  
N Thompson ◽  
G Jenkins ◽  
...  
Keyword(s):  
Natural History ◽  
Idiopathic Pulmonary Fibrosis ◽  
Pulmonary Fibrosis ◽  
Population Based ◽  
History Of ◽  
The Impact

Bilateral versus single lung transplantation for idiopathic pulmonary fibrosis

2013 ◽  
Vol 61 (S 01) ◽  
Author(s):  
S Lehmann ◽  
S Leontyev ◽  
J Garbade ◽  
MJ Barten ◽  
P von Samson ◽  
...  
Keyword(s):  
Idiopathic Pulmonary Fibrosis ◽  
Pulmonary Fibrosis ◽  
Lung Transplantation ◽  
Single Lung Transplantation

Interactions between Cigarette Smoking and the Natural History of Idiopathic Pulmonary Fibrosis

CHEST Journal ◽  
1990 ◽  
Vol 98 (1) ◽  
pp. 71-76 ◽  
Author(s):  
Hubert De Cremoux ◽  
Jean-François Bernaudin ◽  
Philippe Laurent ◽  
Patrick Brochard ◽  
Jean Bignon
Keyword(s):  
Natural History ◽  
Idiopathic Pulmonary Fibrosis ◽  
Pulmonary Fibrosis ◽  
Cigarette Smoking ◽  
History Of

scholarly journals Role of atmospheric pollution on the natural history of idiopathic pulmonary fibrosis

Thorax ◽  
2017 ◽  
Vol 73 (2) ◽  
pp. 145-150 ◽  
Author(s):  
Lucile Sesé ◽  
Hilario Nunes ◽  
Vincent Cottin ◽  
Shreosi Sanyal ◽  
Morgane Didier ◽  
...  
Keyword(s):  
Air Pollution ◽  
Natural History ◽  
Idiopathic Pulmonary Fibrosis ◽  
Pulmonary Fibrosis ◽  
Disease Progression ◽  
Air Pollutant ◽  
Rapid Decline ◽  
History Of ◽  
The Impact

IntroductionIdiopathic pulmonary fibrosis (IPF) has an unpredictable course corresponding to various profiles: stability, physiological disease progression and rapid decline. A minority of patients experience acute exacerbations (AEs). A recent study suggested that ozone and nitrogen dioxide might contribute to the occurrence of AE. We hypothesised that outdoor air pollution might influence the natural history of IPF.MethodsPatients were selected from the French cohort COhorte FIbrose (COFI), a national multicentre longitudinal prospective cohort of IPF (n=192). Air pollutant levels were assigned to each patient from the air quality monitoring station closest to the patient’s geocoded residence. Cox proportional hazards model was used to evaluate the impact of air pollution on AE, disease progression and death.ResultsOnset of AEs was significantly associated with an increased mean level of ozone in the six preceding weeks, with an HR of 1.47 (95% CI 1.13 to 1.92) per 10 µg/m3 (p=0.005). Cumulative levels of exposure to particulate matter PM10 and PM2.5 were above WHO recommendations in 34% and 100% of patients, respectively. Mortality was significantly associated with increased levels of exposure to PM10 (HR=2.01, 95% CI 1.07 to 3.77) per 10 µg/m3 (p=0.03), and PM2.5 (HR=7.93, 95% CI 2.93 to 21.33) per 10 µg/m3 (p<0.001).ConclusionThis study suggests that air pollution has a negative impact on IPF outcomes, corroborating the role of ozone on AEs and establishing, for the first time, the potential role of long-term exposure to PM10 and PM2.5 on overall mortality.

The natural history of idiopathic pulmonary fibrosis in a large European population: the role of age, sex and comorbidities

2021 ◽  
Author(s):  
Antonella Caminati ◽  
Fabiana Madotto ◽  
Sara Conti ◽  
Giancarlo Cesana ◽  
Lorenzo Mantovani ◽  
...  
Keyword(s):  
Natural History ◽  
Idiopathic Pulmonary Fibrosis ◽  
Pulmonary Fibrosis ◽  
European Population ◽  
History Of

scholarly journals Acute worsening of native lung fibrosis after single lung transplantation for pulmonary fibrosis: two case reports

2022 ◽  
Vol 16 (1) ◽  
Author(s):  
Tiphaine Goletto ◽  
Sixtine Decaux ◽  
Vincent Bunel ◽  
Gaëlle Weisenburger ◽  
Jonathan Messika ◽  
...  
Keyword(s):  
Respiratory Failure ◽  
Idiopathic Pulmonary Fibrosis ◽  
Pulmonary Fibrosis ◽  
Lung Transplantation ◽  
Viral Infection ◽  
Lung Fibrosis ◽  
Case Reports ◽  
Rapid Progression ◽  
Single Lung Transplantation ◽  
Native Lung

Abstract Background In patients receiving single lung transplantation for idiopathic pulmonary fibrosis, worsening of fibrosis of the native lung is usually progressive over time, with no significant effects on gas exchange. Case presentation Here, we describe the cases of two Caucasian male recipients of single lung transplants for idiopathic pulmonary fibrosis, 65 and 62 years of age, who exhibited acute worsening of lung fibrosis after an episode of serious viral infection (cytomegalovirus primo-infection in one case and COVID-19 in the other). In both cases, along with opacification of the native lung over several days, the patients presented acute respiratory failure that required the use of high-flow nasal oxygen therapy. Eventually, hypoxemic respiratory failure resolved, but with rapid progression of fibrosis of the native lung. Conclusion We conclude that acute worsening of fibrosis on the native lung secondary to a severe viral infection should be added to the list of potential complications developing on the native lung after single lung transplantation for idiopathic pulmonary fibrosis.

Treprostinil to Reverse Pulmonary Hypertension Associated With Idiopathic Pulmonary Fibrosis as a Bridge to Single-Lung Transplantation

2009 ◽  
Vol 28 (9) ◽  
pp. 964-967 ◽  
Author(s):  
Rajeev Saggar ◽  
Shelley S. Shapiro ◽  
David J. Ross ◽  
Michael C. Fishbein ◽  
David A. Zisman ◽  
...  
Keyword(s):  
Pulmonary Hypertension ◽  
Idiopathic Pulmonary Fibrosis ◽  
Pulmonary Fibrosis ◽  
Lung Transplantation ◽  
Single Lung Transplantation
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