scholarly journals The Murine Femoral Bone Graft Model and a Semiautomated Histomorphometric Analysis Tool

2014 ◽  
pp. 45-59 ◽  
Author(s):  
Robinder S. Dhillon ◽  
Longze Zhang ◽  
Edward M. Schwarz ◽  
Brendan F. Boyce ◽  
Chao Xie
Keyword(s):  
Bone Graft ◽  
Analysis Tool ◽  
Histomorphometric Analysis ◽  
Femoral Bone

Retrograde Femoral Bone Graft Acquisition Using the Reamer–Irrigator–Aspirator

2018 ◽  
Vol 28 (3) ◽  
pp. 181-185
Author(s):  
Benjamin C. Taylor ◽  
Jacob J. Triplet ◽  
David Bird Johnson ◽  
Barry Dale Sharpe ◽  
Brian Sullivan ◽  
...  
Keyword(s):  
Bone Graft ◽  
Femoral Bone

Bone Graft and Substitutes Associated with Titanium Dome for Vertical Bone Formation in Osseointegrated Implants: Histomorphometric Analysis in Dogs

2018 ◽  
Vol 33 (2) ◽  
pp. 311-318 ◽  
Author(s):  
Mario Zendron ◽  
Matheus Cardoso ◽  
Giovana Veronesi ◽  
Daniel de Resende ◽  
Carla Damante ◽  
...  
Keyword(s):  
Bone Formation ◽  
Bone Graft ◽  
Histomorphometric Analysis ◽  
Osseointegrated Implants

Retrograde Versus Antegrade Femoral Bone Graft Harvesting Using the Reamer–Irrigator–Aspirator

2015 ◽  
Vol 29 (8) ◽  
pp. 370-372 ◽  
Author(s):  
Richard L. Davis ◽  
Benjamin C. Taylor ◽  
Nathan Johnson ◽  
Jason R. Ferrel ◽  
Joaquin Castaneda
Keyword(s):  
Bone Graft ◽  
Femoral Bone ◽  
Bone Graft Harvesting

Influence of the Reamer-Irrigator-Aspirator diameter on femoral bone strength and amount of harvested bone graft – a biomechanical cadaveric study

Injury ◽  
2020 ◽  
Vol 51 (12) ◽  
pp. 2846-2850
Author(s):  
Nina Schmitz ◽  
Dominic Gehweiler ◽  
Dirk Wähnert ◽  
Ivan Zderic ◽  
Leonard Grünwald ◽  
...  
Keyword(s):  
Bone Graft ◽  
Bone Strength ◽  
Cadaveric Study ◽  
Femoral Bone

Evaluation of the Bone Healing Process Utilizing Platelet-Rich Plasma Activated by Thrombin and Calcium Chloride: A Histologic Study in Rabbit Calvaria

2013 ◽  
Vol 39 (1) ◽  
pp. 14-21 ◽  
Author(s):  
Walter Betoni-Junior ◽  
Paula Dechichi ◽  
Jônatas Caldeira Esteves ◽  
Darceny Zanetta-Barbosa ◽  
Aparecido Eurípedes Onório Magalhães
Keyword(s):  
Bone Graft ◽  
Calcium Chloride ◽  
Bone Healing ◽  
Bone Repair ◽  
Platelet Rich Plasma ◽  
Healing Process ◽  
Bone Defects ◽  
Histomorphometric Analysis ◽  
Histologic Study ◽  
Vascularized Bone

To evaluate the bone healing of defects filled with particulate bone graft in combination with platelet-rich plasma (PRP), added with a mixture of calcium chloride and thrombin or just calcium chloride. Two 5-mm bone defects were created in the calvaria of 24 rabbits. Each defect was filled with particulate bone graft and PRP. In one defect the PRP was activated by a mixture of calcium chloride and thrombin; in the other, PRP was activated by calcium chloride only. The animals were euthanized 1, 2, 4, and 8 weeks after the surgeries, and the calvaria was submitted to histologic processing for histomorphometric analysis. The qualitative analysis has shown that both defects presented the same histologic characteristics so that a better organized, more mature, and well-vascularized bone tissue was noticed in the eighth week. A good bone repair was achieved using either the mixture of calcium chloride and thrombin or the calcium chloride alone as a restarting agent of the coagulation process.

scholarly journals Safety and efficacy of a novel retrograde route for femoral bone graft harvesting by Reamer-Irrigator-Aspirator: a pilot study on 24 patients

2022 ◽  
Vol 16 (1) ◽  
Author(s):  
Fernando Bidolegui ◽  
Sebastián Pereira ◽  
Cristina Irigoyen ◽  
Robinson Esteves Pires
Keyword(s):  
Postoperative Pain ◽  
Bone Graft ◽  
Iliac Crest ◽  
Bone Defects ◽  
Femoral Bone ◽  
Femoral Route ◽  
Bone Graft Harvesting ◽  
Post Traumatic ◽  
Graft Volume

Abstract Background The Reamer–Irrigator–Aspirator system was initially developed to reduce fat embolism and thermic necrosis during reamed intramedullary nail fixation of femoral shaft fractures. Currently, this system is used in extended applications including accessing large volume of autologous bone graft, as alternative for iliac crest harvesting. Antegrade femoral bone graft harvesting using the Reamer-Irrigator-Aspirator system is considered the standard technique. The aim of our study is to evaluate the efficacy (bone graft volume) and the complications (blood loss, postoperative pain, and incidence of iatrogenic fractures) of the Reamer–Irrigator–Aspirator system through the retrograde femoral route in a series of patients with post-traumatic bone defects or nonunions. Methods A non-controlled single center retrospective observational cohort study was conducted in a level1 trauma center to evaluate all patients who were treated using the RIA system. Between November 2015 and May 2019, 24 patients (8 women and 16 men; mean age: 41 years [range 27–55 years]) with bone defects or nonunions underwent bone graft harvesting using the Reamer–Irrigator–Aspirator system through retrograde femoral route. Postoperative pain, complications, and bone graft volume were analyzed. Inclusion criteria was patients older than 18 years with a diagnosis of post-traumatic bone defect or associated tibial or femoral nonunion, with minimum 6-months follow, treated using the RIA. We hypothesized that the retrograde route of the RIA system is a safe and efficacious method for bone harvesting. Results The average volume of collected graft was 45 cc (range 30–60 cc). In 83% of the cases, bone grafting was sufficient, while in 17% it was necessary to add iliac crest bone graft to completely fill the bone defect. A mean drop in postoperative hemoglobin of 4.1 g / dL (range 0.5–6.0 g / dL) was evidenced. In 4 cases (33%), a unit of packed red blood cells was required. Regarding postoperative pain, visual analogue scale after 3 months postoperatively was 1.6 in average. After 6 months, the value has decreased to 0.4. There were no perioperative or postoperative complications at 6-month follow-up. Conclusion In this limited case series, large volumes of bone graft were harvested using the retrograde route of the RIA system and there were no intra-/ postoperative complications observed at 6-month follow-up. Therefore this novel technique appears safe and efficacious. However, it’s important to highlight that future prospective controlled studies are necessary to validate the insights from this pilot study.

Guiding Bone Regeneration with a Novel Biodegradable Polymeric Membrane and Bioceramic Bone Grafts around Dental Implants

2007 ◽  
Vol 330-332 ◽  
pp. 1417-1420
Author(s):  
L. Li ◽  
C.Y. Bao ◽  
Guo Min Ou ◽  
W.C. Chen ◽  
X.J. Zhang ◽  
...  
Keyword(s):  
Bone Graft ◽  
Bone Regeneration ◽  
Dental Implants ◽  
Polymeric Membrane ◽  
Collagen Membrane ◽  
Graft Material ◽  
The Novel ◽  
Histomorphometric Analysis ◽  
Mongrel Dog ◽  
Collagen Membranes

The aim of this study is to evaluate treatment effects of novel GBR membranes (PDLLA membranes) applied to bony defects around dental implants on new bone regeneration alone or in combination with bioceramic bone graft (BIO-OSS®) on the mongrel dog model in comparison with collagen membrane (BIO-GIDE®) and therefore to assess the clinical values of the novel GBR membranes and bioceramic bone graft material in dental implantology. 6 implants were placed in bilateral mandibular of each mongrel dog after preparation of mid- crestal defects. The defects on one side were covered with PDLLA membranes alone or with bone graft, while the contra-lateral sides received collagen membranes alone or with bone graft. These animals were sacrificed at 2, 4, 8,12 weeks post the GBR-operation. And gross sample examination, standardized radiographs, 99mTc-MDP SPECT and histomorphometric analysis were taken. All examinations showed similar amounts of newly formed bone beneath both types of barriers. The PDLLA or collagen membrane with bone graft groups showed better results than the membrane used alone groups. The results indicated that PDLLA membranes especially with bioceramic bone graft presented an improved response in dealing with bony defects around implants.

A gastrocnemius-pedicled femoral bone graft in resection arthrodesis at the knee

1988 ◽  
Vol 70-B (3) ◽  
pp. 354-357 ◽  
Author(s):  
RW Pho ◽  
MH Patterson ◽  
K Satku
Keyword(s):  
Bone Graft ◽  
Femoral Bone
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