Role of Stroma in Pancreatic Cancer

2021 ◽  
pp. 251-265
Author(s):  
Malin Sund
Keyword(s):  
Pancreatic Cancer

PET/CT IN THE DIAGNOSIS OF PANCREATIC CANCER: LITERATURE REVIEW

2018 ◽  
pp. 57-67
Author(s):  
P. E. Tulin ◽  
M. B. Dolgushin ◽  
D. I. Nevzorov ◽  
P. V. Kochergin ◽  
Yu. I. Patyutko
Keyword(s):  
Pancreatic Cancer ◽  
Literature Review ◽  
Pancreatic Neoplasms ◽  
Poor Prognosis ◽  
Modern Imaging ◽  
Pet Ct

Pancreatic cancer has a poor prognosis, often because most pancreatic neoplasms are found to be unresectable at diagnosis. Early staging of the tumor process can change the tactics of treatment and affect the survival of patients. The purpose of this review is to provide an overview of pancreatic cancer and the role of modern imaging in its diagnosis with an emphasis on PET/CT with a various radiopharmaceuticals.

Role of myeloperoxidase in relationship between smoking and risk of pancreatic cancer

2012 ◽  
Vol 32 (2) ◽  
pp. 183-185
Author(s):  
Xin-xin FU ◽  
Zhao-shen LI ◽  
Zhen-dong JIN ◽  
Hai-tao CHEN ◽  
Wei ZHU ◽  
...  
Keyword(s):  
Pancreatic Cancer

Diagnostic pancreatic cancer: the role of percutaneous biopsy and CT

2007 ◽  
Vol 31 (3) ◽  
pp. 221
Author(s):  
Z. Amin ◽  
B. Theis ◽  
R.C.G. Russell ◽  
C. House ◽  
M. Novelli ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Percutaneous Biopsy

scholarly journals A Proteomic Study on the Personalized Protein Corona of Liposomes. Relevance for Early Diagnosis of Pancreatic DUCTAL Adenocarcinoma and Biomarker Detection

2021 ◽  
Vol 2 (2) ◽  
pp. 82-93
Author(s):  
Luca Digiacomo ◽  
Francesca Giulimondi ◽  
Daniela Pozzi ◽  
Alessandro Coppola ◽  
Vincenzo La Vaccara ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Early Diagnosis ◽  
Pancreatic Ductal Adenocarcinoma ◽  
Protein Corona ◽  
Detection Sensitivity ◽  
Ductal Adenocarcinoma ◽  
Protein Biomarkers ◽  
Ca 19.9 ◽  
Proteomic Study

Due to late diagnosis, high incidence of metastasis, and poor survival rate, pancreatic cancer is one of the most leading cause of cancer-related death. Although manifold recent efforts have been done to achieve an early diagnosis of pancreatic cancer, CA-19.9 is currently the unique biomarker that is adopted for the detection, despite its limits in terms of sensitivity and specificity. To identify potential protein biomarkers for pancreatic ductal adenocarcinoma (PDAC), we used three model liposomes as nanoplatforms that accumulate proteins from human plasma and studied the composition of this biomolecular layer, which is known as protein corona. Indeed, plasma proteins adsorb on nanoparticle surface according to their abundance and affinity to the employed nanomaterial, thus even small differences between healthy and PDAC protein expression levels can be, in principle, detected. By mass spectrometry experiments, we quantified such differences and identified possible biomarkers for PDAC. Some of them are already known to exhibit different expressions in PDAC proteomes, whereas the role of other relevant proteins is still not clear. Therefore, we predict that the employment of nanomaterials and their protein corona may represent a useful tool to amplify the detection sensitivity of cancer biomarkers, which may be used for the early diagnosis of PDAC, with clinical implication for the subsequent therapy in the context of personalized medicine.

scholarly journals Systematic Review of the Integrative Medicine Recommendations for Patients with Pancreatic Cancer

Surgeries ◽  
2021 ◽  
Vol 2 (2) ◽  
pp. 216-230
Author(s):  
Andrew A. Gumbs ◽  
Manana Gogol ◽  
Gaya Spolverato ◽  
Hebatallah Taher ◽  
Elie K. Chouillard
Keyword(s):  
Systematic Review ◽  
Pancreatic Cancer ◽  
Integrative Medicine ◽  
Lifestyle Changes ◽  
Randomized Controlled ◽  
Nutrition Supplementation ◽  
Traditional Therapies ◽  
Traditional Approaches

Introduction: Integrative medicine (IM) is a relatively new field where non-traditional therapies with peer-reviewed evidence are incorporated or integrated with more traditional approaches. Methods: A systematic review of the literature from the last 10 years was done by searching clinical trials and randomized-controlled trials on Pubmed that discuss nutrition, supplementation, and lifestyle changes associated with “Pancreatic Cancer.” Results: Only 50 articles ultimately met the inclusion criteria for this review. A total of 15 articles discussed the role of obesity and 10 discussed the influence of stress in increasing the risk of pancreatic cancer. Six discussed the potential beneficial role of Vitamins, 5 of cannabinoids, 4 an anti-inflammatory diet, 3 of nut consumption, 2 of green tea consumption, 2 of curcumin supplementation, 1 role of melatonin, and 1 of probiotics. One article each was found on the theoretical benefits of adhering to either a Mediterranean or ketogenic diet. Discussion: As more surgeons become interested in IM, it is hoped that more diseases where the curative treatment is mainly surgical can benefit from the all-encompassing principles of IM in an effort to improve quality of life and survival in patients with pancreatic cancer.

Surgical treatment of pancreatic cancer: The role of adjuvant and multimodal therapies

2007 ◽  
Vol 33 (7) ◽  
pp. 817-823 ◽  
Author(s):  
J. Kleeff ◽  
C.W. Michalski ◽  
H. Friess ◽  
M.W. Büchler
Keyword(s):  
Pancreatic Cancer ◽  
Surgical Treatment

The Role of Transition Metal Ions in Ascorbate-Induced Cytotoxicity in Pancreatic Cancer

2014 ◽  
Vol 76 ◽  
pp. S124
Author(s):  
Juan Du ◽  
Brett A Wagner ◽  
Garry R Buettner ◽  
Joseph J Cullen
Keyword(s):  
Pancreatic Cancer ◽  
Transition Metal ◽  
Metal Ions ◽  
Transition Metal Ions
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