Diarrheal Mechanisms and the Role of Intestinal Barrier Dysfunction in Campylobacter Infections

2021 ◽  
pp. 203-231
Author(s):  
Fábia Daniela Lobo de Sá ◽  
Jörg-Dieter Schulzke ◽  
Roland Bücker
Keyword(s):  
Intestinal Barrier ◽  
Barrier Dysfunction ◽  
Intestinal Barrier Dysfunction ◽  
Campylobacter Infections

scholarly journals ROLE OF NON-MUSCLE MYOSIN LIGHT CHAIN KINASE IN NEUTROPHIL-MEDIATED INTESTINAL BARRIER DYSFUNCTION DURING THERMAL INJURY

Shock ◽  
2012 ◽  
Vol 38 (4) ◽  
pp. 436-443 ◽  
Author(s):  
Mingzhang Guo ◽  
Sarah Y. Yuan ◽  
Bert J. Frederich ◽  
Chongxiu Sun ◽  
Qiang Shen ◽  
...  
Keyword(s):  
Light Chain ◽  
Myosin Light Chain Kinase ◽  
Myosin Light Chain ◽  
Thermal Injury ◽  
Intestinal Barrier ◽  
Barrier Dysfunction ◽  
Intestinal Barrier Dysfunction ◽  
Muscle Myosin

scholarly journals TREM-1 Promotes Pancreatitis-Associated Intestinal Barrier Dysfunction

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Shengchun Dang ◽  
Yao Shen ◽  
Kai Yin ◽  
Jianxin Zhang
Keyword(s):  
Innate Immunity ◽  
Animal Model ◽  
Acute Pancreatitis ◽  
Intestinal Barrier ◽  
Related Protein ◽  
Barrier Dysfunction ◽  
Intestinal Barrier Dysfunction ◽  
Risk Of Mortality ◽  
Membrane Bound

Severe acute pancreatitis (SAP) can cause intestinal barrier dysfunction (IBD), which significantly increases the disease severity and risk of mortality. We hypothesized that the innate immunity- and inflammatory-related protein-triggering receptor expressed on myeloid cells-1 (TREM-1) contributes to this complication of SAP. Thus, we investigated the effect of TREM-1 pathway modulation on a rat model of pancreatitis-associated IBD. In this study we sought to clarify the role of TREM-1 in the pathophysiology of intestinal barrier dysfunction in SAP. Specifically, we evaluated levels of serum TREM-1 and membrane-bound TREM-1 in the intestine and pancreas from an animal model of experimentally induced SAP. TREM-1 pathway blockade by LP17 treatment may suppress pancreatitis-associated IBD and ameliorate the damage to the intestinal mucosa barrier.

Role of melatonin in sleep deprivation‐induced intestinal barrier dysfunction in mice

2019 ◽  
pp. e12574 ◽  
Author(s):  
Ting Gao ◽  
Zixu Wang ◽  
Yulan Dong ◽  
Jing Cao ◽  
Rutao Lin ◽  
...  
Keyword(s):  
Sleep Deprivation ◽  
Intestinal Barrier ◽  
Barrier Dysfunction ◽  
Intestinal Barrier Dysfunction

scholarly journals Critical role of P-selectin-dependent leukocyte recruitment in endotoxin-induced intestinal barrier dysfunction in mice

2007 ◽  
Vol 56 (5) ◽  
pp. 189-194 ◽  
Author(s):  
P. Mangell ◽  
A. Mihaescu ◽  
Y. Wang ◽  
R. Schramm ◽  
B. Jeppsson ◽  
...  
Keyword(s):  
Critical Role ◽  
Intestinal Barrier ◽  
Leukocyte Recruitment ◽  
Barrier Dysfunction ◽  
Intestinal Barrier Dysfunction

scholarly journals The role of I-FABP as a biomarker of intestinal barrier dysfunction driven by gut microbiota changes in obesity

2016 ◽  
Vol 13 (1) ◽  
Author(s):  
Eva Lau ◽  
Cláudia Marques ◽  
Diogo Pestana ◽  
Mariana Santoalha ◽  
Davide Carvalho ◽  
...  
Keyword(s):  
Gut Microbiota ◽  
Intestinal Barrier ◽  
Barrier Dysfunction ◽  
Intestinal Barrier Dysfunction
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