A Patient-Specific EMG-Driven Musculoskeletal Model for Improving the Effectiveness of Robotic Neurorehabilitation

Author(s):  
Ye Ma ◽  
Sheng Quan Xie ◽  
Yanxin Zhang
2019 ◽  
Vol 13 (4) ◽  
Author(s):  
Emerson Paul Grabke ◽  
Kei Masani ◽  
Jan Andrysek

Abstract Many individuals with lower limb amputations or neuromuscular impairments face mobility challenges attributable to suboptimal assistive device design. Forward dynamic modeling and simulation of human walking using conventional biomechanical gait models offer an alternative to intuition-based assistive device design, providing insight into the biomechanics underlying pathological gait. Musculoskeletal models enable better understanding of prosthesis and/or exoskeleton contributions to the human musculoskeletal system, and device and user contributions to both body support and propulsion during gait. This paper reviews current literature that have used forward dynamic simulation of clinical population musculoskeletal models to perform assistive device design optimization using optimal control, optimal tracking, computed muscle control (CMC) and reflex-based control. Musculoskeletal model complexity and assumptions inhibit forward dynamic musculoskeletal modeling in its current state, hindering computational assistive device design optimization. Future recommendations include validating musculoskeletal models and resultant assistive device designs, developing less computationally expensive forward dynamic musculoskeletal modeling methods, and developing more efficient patient-specific musculoskeletal model generation methods to enable personalized assistive device optimization.


2004 ◽  
Vol 6 (1) ◽  
pp. 13-21
Author(s):  
Yoshito Otake ◽  
Naoki Suzuki ◽  
Asaki Hattori ◽  
Hidenobu Miki ◽  
Mitsuyoshi Yamamura ◽  
...  

2004 ◽  
Vol 1268 ◽  
pp. 591-596 ◽  
Author(s):  
Y Otake ◽  
N Suzuki ◽  
A Hattori ◽  
H Miki ◽  
M Yamamura ◽  
...  

Author(s):  
Emerson Paul Grabke ◽  
Jan Andrysek

Lower-limb amputees can suffer from preventable pain and bone disorders attributable to suboptimal prosthesis design. Predictive modelling and simulation of human walking using conventional biomechanical gait models offer an alternative to intuition-based prosthesis design, providing insight into the biomechanics underlying pathological gait. Musculoskeletal models additionally enable understanding of prosthesis contributions to the human musculoskeletal system, and both prosthesis and individual muscle contributions to body support and propulsion during gait. Based on this review, forward dynamic simulation of amputee musculoskeletal models have been used to perform prosthesis design optimization using optimal control and reflex-based control. Musculoskeletal model complexity and assumptions inhibit fully predictive musculoskeletal modelling in its current state, hindering computational prosthesis design optimization. Future recommendations include validating musculoskeletal models and resultant optimized prosthesis designs, developing less computationally-expensive predictive musculoskeletal modelling methods, and developing more efficient patient-specific musculoskeletal model generation methods to enable personalized prosthesis optimization.


2013 ◽  
Vol 61 (S 01) ◽  
Author(s):  
M Kaur ◽  
N Sprunk ◽  
U Schreiber ◽  
R Lange ◽  
J Weipert ◽  
...  

2007 ◽  
Vol 46 (01) ◽  
pp. 38-42 ◽  
Author(s):  
V. Schulz ◽  
I. Nickel ◽  
A. Nömayr ◽  
A. H. Vija ◽  
C. Hocke ◽  
...  

SummaryThe aim of this study was to determine the clinical relevance of compensating SPECT data for patient specific attenuation by the use of CT data simultaneously acquired with SPECT/CT when analyzing the skeletal uptake of polyphosphonates (DPD). Furthermore, the influence of misregistration between SPECT and CT data on uptake ratios was investigated. Methods: Thirty-six data sets from bone SPECTs performed on a hybrid SPECT/CT system were retrospectively analyzed. Using regions of interest (ROIs), raw counts were determined in the fifth lumbar vertebral body, its facet joints, both anterior iliacal spinae, and of the whole transversal slice. ROI measurements were performed in uncorrected (NAC) and attenuation-corrected (AC) images. Furthermore, the ROI measurements were also performed in AC scans in which SPECT and CT images had been misaligned by 1 cm in one dimension beforehand (ACX, ACY, ACZ). Results: After AC, DPD uptake ratios differed significantly from the NAC values in all regions studied ranging from 32% for the left facet joint to 39% for the vertebral body. AC using misaligned pairs of patient data sets led to a significant change of whole-slice uptake ratios whose differences ranged from 3,5 to 25%. For ACX, the average left-to-right ratio of the facet joints was by 8% and for the superior iliacal spines by 31% lower than the values determined for the matched images (p <0.05). Conclusions: AC significantly affects DPD uptake ratios. Furthermore, misalignment between SPECT and CT may introduce significant errors in quantification, potentially also affecting leftto- right ratios. Therefore, at clinical evaluation of attenuation- corrected scans special attention should be given to possible misalignments between SPECT and CT.


1989 ◽  
Vol 28 (02) ◽  
pp. 69-77 ◽  
Author(s):  
R. Haux

Abstract:Expert systems in medicine are frequently restricted to assisting the physician to derive a patient-specific diagnosis and therapy proposal. In many cases, however, there is a clinical need to use these patient data for other purposes as well. The intention of this paper is to show how and to what extent patient data in expert systems can additionally be used to create clinical registries and for statistical data analysis. At first, the pitfalls of goal-oriented mechanisms for the multiple usability of data are shown by means of an example. Then a data acquisition and inference mechanism is proposed, which includes a procedure for controlling selection bias, the so-called knowledge-based attribute selection. The functional view and the architectural view of expert systems suitable for the multiple usability of patient data is outlined in general and then by means of an application example. Finally, the ideas presented are discussed and compared with related approaches.


1998 ◽  
Vol 37 (02) ◽  
pp. 171-178 ◽  
Author(s):  
B. Glassman ◽  
B. K. Rimer

AbstractIn more and more medical settings, physicians have less and less time to be effective communicators. To be effective, they need accurate, current information about their patients. Tailored health communications can facilitate positive patient-provider communications and foster behavioral changes conducive to health. Tailored communications (TCs) are produced for an individual based on information about that person. The focus of this report is on tailored print communications (TPCs). TPCs also enhance the process of evaluation, because they require a database and the collection of patient-specific information. We present a Tailoring Model for Primary Care that describes the steps involved in creating TPCs. We also provide examples from three ongoing studies in which TPCs are being used in order to illustrate the kinds of variables used for tailoring the products that are developed and how evaluation is conducted. TPCs offer opportunities to expand the reach of health professionals and to give personalized, individualized massages in an era of shrinking professional contact time.


Sign in / Sign up

Export Citation Format

Share Document