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Andréa Tedesco Faccio ◽  
Gisele André Baptista Canuto ◽  
Pedro Luis Rocha da Cruz ◽  
Henrique Caracho Ribeiro ◽  
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Combining integrated systems-biology approaches with intervention-based experimental design provides a higher-resolution path forward for microbiome research

2019 ◽  
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Carlee S. McClintock ◽  
Ralph Lydic ◽  
Helen A. Baghdoyan ◽  
James J. Choo ◽  
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Keyword(s):  
Systems Biology ◽  
High Resolution ◽  
Experimental Design ◽  
Integrated Systems ◽  
Microbiome Research ◽  
Constructive Criticism

Abstract The Hooks et al. review of microbiota-gut-brain (MGB) literature provides a constructive criticism of the general approaches encompassing MGB research. This commentary extends their review by: (a) highlighting capabilities of advanced systems-biology “-omics” techniques for microbiome research and (b) recommending that combining these high-resolution techniques with intervention-based experimental design may be the path forward for future MGB research.

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Systems Biology

Using integrative lipid systems biology to understand the role of Liver X receptors (LXRs) in male reproduction

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Sheba Jarvis ◽  
Lee Gethings ◽  
Raffaella Gadeleta ◽  
Emmanuelle Claude ◽  
Robert Winston ◽  
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Male Reproduction ◽  
Liver X Receptors ◽  
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Bridging structural and systems biology through academic and industrial career experiences

2016 ◽  
Vol 4 (Suppl. 1) ◽  
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