Metal Allergy and Palmoplantar Pustulosis

Background: In 2007 the International Psoriasis Council considered palmoplantar pustulosis (PPP) a condition separate from psoriasis, and several authors maintain that PPP is a reactive process to metal contact allergies independent from psoriasis. Objectives: To evaluate the frequency of allergies and psoriasis in patients with PPP and to determine the role of allergens in PPP. Methods: A systematic search of the English databases (PubMed and Web of Science) from January 1964 to August 2018 to identify all patients affected by PPP and allergies and/or psoriasis. Results: In total, 16 publications describing a total of 519 patients with PPP were evaluated and 122 cases of concomitant PPP and metal allergy were found. The frequency of allergies among patients with PPP was 22.7%; between the identified allergens, 84.3% of cases correspond to metal allergies. In 65.1% of metal allergies, an improvement in PPP was seen after withdrawal of contact. The concomitant presence of psoriasis was recorded in 18% of the cases. Conclusion: There is some evidence to support the association of PPP with metal allergies but also with psoriasis, suggesting the role of metal allergens as a trigger factor in patients with PPP.

Download Full-text

A study on involvement of metal allergy in the pathogenesis of oral lichen planus and palmoplantar pustulosis

Japanese Journal of Oral & Maxillofacial Surgery ◽

10.5794/jjoms.58.718 ◽

2012 ◽

Vol 58 (12) ◽

pp. 718-722

Author(s):

Masafumi MORIYAMA ◽

Shiori KANDA ◽

Shintaro KAWANO ◽

Koichiro TATEISHI ◽

Yuichi GOTO ◽

...

Keyword(s):

Lichen Planus ◽

Oral Lichen Planus ◽

Metal Allergy ◽

Palmoplantar Pustulosis ◽

Oral Lichen

Download Full-text

The relationship between dental metal allergy, periodontitis, and palmoplantar pustulosis: An observational study

Journal of Prosthodontic Research ◽

10.2186/jpr.jpr_d_20_00307 ◽

2021 ◽

Author(s):

Yurina Takaoka ◽

Yosuke Akiba ◽

Masako Nagasawa ◽

Akiko Ito ◽

Yukiko Masui ◽

...

Keyword(s):

Observational Study ◽

Metal Allergy ◽

Palmoplantar Pustulosis ◽

Dental Metal ◽

The Relationship

Download Full-text

Aortic valve replacement in a patient with self-reported systemic multiple metal allergy

General Thoracic and Cardiovascular Surgery ◽

10.1007/s11748-021-01712-3 ◽

2021 ◽

Author(s):

Saori Nagura ◽

Mari Sakai ◽

Hayato Obi ◽

Kazuaki Fukahara

Keyword(s):

Cardiac Surgery ◽

Aortic Valve ◽

Aortic Stenosis ◽

Aortic Valve Replacement ◽

Patch Test ◽

Valve Replacement ◽

Severe Aortic Stenosis ◽

Metal Allergy ◽

Palmoplantar Pustulosis ◽

Patient Reported

AbstractWe report our experience with aortic valve replacement in a patient with severe aortic stenosis who had self-reported allergies to multiple metals. The patient was a 74-year-old man. He developed palmoplantar pustulosis after using a dental prosthesis, and a patch test revealed reactions to several metals; therefore, he was diagnosed with systemic metal allergy. His condition progressed to severe aortic stenosis, and bioprosthetic aortic valve replacement was planned. The Avalus valve (Medtronic, Minneapolis, MN, USA) was selected for aortic valve replacement, since the patient reported having allergies to several metals. While most devices used in cardiac surgery contain some amount of metal, the Avalus bioprosthetic valve does not contain metal in the stent and has been extremely useful for aortic valve replacement in patients with suspected metal allergies.

Download Full-text