Shape Classification Using Combined Features

Author(s):  
Laksono Kurnianggoro ◽  
Wahyono ◽  
Alexander Filonenko ◽  
Kang-Hyun Jo
2009 ◽  
Vol 29 (10) ◽  
pp. 2710-2712 ◽  
Author(s):  
Li-qiang DU ◽  
Peng JIA ◽  
Zong-tan ZHOU ◽  
De-wen HU

2013 ◽  
Vol 32 (10) ◽  
pp. 2840-2842 ◽  
Author(s):  
Zhen SONG ◽  
Yong-feng YAN

2020 ◽  
Vol 15 ◽  
Author(s):  
Dicle Yalcin ◽  
Hasan H. Otu

Background: Epigenetic repression mechanisms play an important role in gene regulation, specifically in cancer development. In many cases, a CpG island’s (CGI) susceptibility or resistance to methylation are shown to be contributed by local DNA sequence features. Objective: To develop unbiased machine learning models–individually and combined for different biological features–that predict the methylation propensity of a CGI. Methods: We developed our model consisting of CGI sequence features on a dataset of 75 sequences (28 prone, 47 resistant) representing a genome-wide methylation structure. We tested our model on two independent datasets that are chromosome (132 sequences) and disease (70 sequences) specific. Results: We provided improvements in prediction accuracy over previous models. Our results indicate that combined features better predict the methylation propensity of a CGI (area under the curve (AUC) ~0.81). Our global methylation classifier performs well on independent datasets reaching an AUC of ~0.82 for the complete model and an AUC of ~0.88 for the model using select sequences that better represent their classes in the training set. We report certain de novo motifs and transcription factor binding site (TFBS) motifs that are consistently better in separating prone and resistant CGIs. Conclusion: Predictive models for the methylation propensity of CGIs lead to a better understanding of disease mechanisms and can be used to classify genes based on their tendency to contain methylation prone CGIs, which may lead to preventative treatment strategies. MATLAB and Python™ scripts used for model building, prediction, and downstream analyses are available at https://github.com/dicleyalcin/methylProp_predictor.


2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Swetlana G. Meshcheryagina ◽  
Alexey Opaev

Abstract Background In the last decade, enigmatic male-like cuckoo calls have been reported several times in East Asia. These calls exhibited a combination of vocal traits of both Oriental Cuckoo (Cuculus optatus) and Common Cuckoo (Cuculus canorus) advertising calls, and some authors therefore suggested that the enigmatic calls were produced by either Common × Oriental Cuckoo male hybrids or Common Cuckoo males having a gene mutation. However, the exact identity of calling birds are still unknown. Methods We recorded previously unknown male-like calls from three captive Oriental Cuckoo females, and compared these calls with enigmatic vocalizations recorded in the wild as well as with advertising vocalizations of Common and Oriental Cuckoo males. To achieve this, we measured calls automatically. Besides, we video-recorded captive female emitting male-like calls, and compared these recordings with the YouTube recordings of calling males of both Common and Oriental Cuckoos to get insight into the mechanism of call production. Results The analysis showed that female male-like calls recorded in captivity were similar to enigmatic calls recorded in the wild. Therefore, Oriental Cuckoo females might produce the latter calls. Two features of these female calls appeared to be unusual among birds. First, females produced male-like calls at the time of spring and autumn migratory activity and on migration in the wild. Because of this, functional significance of this call remained puzzling. Secondly, the male-like female call unexpectedly combined features of both closed-mouth (closed beak and simultaneous inflation of the ‘throat sac’) and open-mouth (prominent harmonic spectrum and the maximum neck extension observed at the beginning of a sound) vocal behaviors. Conclusions The Cuculus vocalizations outside the reproductive season remain poorly understood. Here, we found for the first time that Oriental Cuckoo females can produce male-like calls in that time. Because of its rarity, this call might be an atavism. Indeed, female male-like vocalizations are still known in non-parasitic tropical and apparently more basal cuckoos only. Therefore, our findings may shed light on the evolution of vocal communication in avian brood parasites.


2017 ◽  
Vol 1 (7) ◽  
pp. 1396-1405 ◽  
Author(s):  
Ji Yang ◽  
Yuting Gao ◽  
Tao Jiang ◽  
Wen Liu ◽  
Chenchen Liu ◽  
...  

Non-substituted and alkyl-substituted triphenylamine–dibenzo[a,c]phenazine adducts (Q1–Q3) showed the combined features of ICT plus AEE, while the alkoxy-substituted Q4–Q5 exhibited obvious AIE effects.


1974 ◽  
Vol 4 (1) ◽  
pp. 85-94 ◽  
Author(s):  
Carl Eberhart ◽  
G.R. Gordh ◽  
John Mack
Keyword(s):  

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