scholarly journals Coding Region Prediction in Genomic Sequences Using a Combination of Digital Signal Processing Approaches

Author(s):  
Aníbal Rodríguez Fuentes ◽  
Juan V. Lorenzo Ginori ◽  
Ricardo Grau Ábalo
2009 ◽  
Vol 4 (1) ◽  
pp. 28-40 ◽  
Author(s):  
Juan Lorenzo-Ginori ◽  
Anibal Rodriguez-Fuentes ◽  
Ricardo Abalo ◽  
Robersy Rodriguez

2019 ◽  
Vol 31 (01) ◽  
pp. 1950002
Author(s):  
Subhajit Kar ◽  
Madhabi Ganguly ◽  
Saptarshi Das

The new research platform on biomedical engineering by Digital Signal Processing (DSP) is playing a vital role in the prediction of protein coding regions (Exons) from genomic sequences with great accuracy. We can determine the protein coding area in DNA sequences with the help of period-3 property. It has been seen that in order to find out the period-3 property, the DFT algorithm is mostly used but in this paper, we have tested FFT algorithm instead of DFT algorithm. DSP is basically concerned with processing numerical sequences. When digital signal processing used in DNA sequences analysis, it requires conversion of base characters sequence to the numerical version. The numerical representation of DNA sequences strongly impacts the biological properties mirrored through the numerical genre. In this work, the proposed technique based on DIT-FFT algorithm has been used to identify the exonic area with the help of integer value representation for transforming the DNA sequences. Digital filters are used to read out period 3 components from the output spectrum and to eliminate the unwanted high frequency noise from DNA sequences. To overcome background noise means to suppress the non-coding regions, i.e., Introns. Proposed algorithm is tested on four nucleotide sequences having single or multiple numbers of exons.


2019 ◽  
pp. 34-39 ◽  
Author(s):  
E.I. Chernov ◽  
N.E. Sobolev ◽  
A.A. Bondarchuk ◽  
L.E. Aristarhova

The concept of hidden correlation of noise signals is introduced. The existence of a hidden correlation between narrowband noise signals isolated simultaneously from broadband band-limited noise is theoretically proved. A method for estimating the latent correlation of narrowband noise signals has been developed and experimentally investigated. As a result of the experiment, where a time frag ent of band-limited noise, the basis of which is shot noise, is used as the studied signal, it is established: when applying the Pearson criterion, there is practically no correlation between the signal at the Central frequency and the sum of signals at mirror frequencies; when applying the proposed method for the analysis of the same signals, a strong hidden correlation is found. The proposed method is useful for researchers, engineers and metrologists engaged in digital signal processing, as well as developers of measuring instruments using a new technology for isolating a useful signal from noise – the method of mirror noise images.


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