2016 ◽  
Vol 52 (4) ◽  
pp. 1536-1554 ◽  
Author(s):  
Yunfei Guo ◽  
Ratnasingham Tharmarasa ◽  
Sreeraman Rajan ◽  
Taek Lyul Song ◽  
Thia Kirubarajan

2021 ◽  
pp. 193229682110182
Author(s):  
Aaron P. Tucker ◽  
Arthur G. Erdman ◽  
Pamela J. Schreiner ◽  
Sisi Ma ◽  
Lisa S. Chow

Successful measurements of interstitial glucose are a key component in providing effective care for patients with diabetes. Recently, there has been significant interest in using neural networks to forecast future glucose values from interstitial measurements collected by continuous glucose monitors (CGMs). While prediction accuracy continues to improve, in this work we investigated the effect of physiological sensor location on neural network blood glucose forecasting. We used clinical data from patients with Type 2 Diabetes who wore blinded FreeStyle Libre Pro CGMs (Abbott) on both their right and left arms continuously for 12 weeks. We trained patient-specific prediction algorithms to test the effect of sensor location on neural network forecasting ( N = 13, Female = 6, Male = 7). In 10 of our 13 patients, we found at least one significant ( P < .05) increase in forecasting error in algorithms which were tested with data taken from a different location than data which was used for training. These reported results were independent from other noticeable physiological differences between subjects (eg, height, age, weight, blood pressure) and independent from overall variance in the data. From these results we observe that CGM location can play a consequential role in neural network glucose prediction.


Water ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 934
Author(s):  
Mariacrocetta Sambito ◽  
Gabriele Freni

In the urban drainage sector, the problem of polluting discharges in sewers may act on the proper functioning of the sewer system, on the wastewater treatment plant reliability and on the receiving water body preservation. Therefore, the implementation of a chemical monitoring network is necessary to promptly detect and contain the event of contamination. Sensor location is usually an optimization exercise that is based on probabilistic or black-box methods and their efficiency is usually dependent on the initial assumption made on possible eligibility of nodes to become a monitoring point. It is a common practice to establish an initial non-informative assumption by considering all network nodes to have equal possibilities to allocate a sensor. In the present study, such a common approach is compared with different initial strategies to pre-screen eligible nodes as a function of topological and hydraulic information, and non-formal 'grey' information on the most probable locations of the contamination source. Such strategies were previously compared for conservative xenobiotic contaminations and now they are compared for a more difficult identification exercise: the detection of nonconservative immanent contaminants. The strategies are applied to a Bayesian optimization approach that demonstrated to be efficient in contamination source location. The case study is the literature network of the Storm Water Management Model (SWMM) manual, Example 8. The results show that the pre-screening and ‘grey’ information are able to reduce the computational effort needed to obtain the optimal solution or, with equal computational effort, to improve location efficiency. The nature of the contamination is highly relevant, affecting monitoring efficiency, sensor location and computational efforts to reach optimality.


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