Localizing Expression of the Three Members of the Nerve Growth Factor Family to Neurons in the Brain

1991 ◽  
pp. 29-38
Author(s):  
L. Olson ◽  
C. Wetmore ◽  
P. Ernfors ◽  
T. Ebendal ◽  
T. Persson
Keyword(s):  
Nerve Growth Factor ◽  
Growth Factor ◽  
Nerve Growth ◽  
The Brain

The mature/pro nerve growth factor ratio is decreased in the brain of diabetic rats: Analysis by ELISA methods

2015 ◽  
Vol 1624 ◽  
pp. 455-468 ◽  
Author(s):  
Marzia Soligo ◽  
Virginia Protto ◽  
Fulvio Florenzano ◽  
Luisa Bracci-Laudiero ◽  
Fabrizio De Benedetti ◽  
...  
Keyword(s):  
Nerve Growth Factor ◽  
Growth Factor ◽  
Diabetic Rats ◽  
Nerve Growth ◽  
Factor Ratio ◽  
The Brain

Mouse nerve growth factor gene: structure and expression

1987 ◽  
Vol 7 (9) ◽  
pp. 3057-3064
Author(s):  
M J Selby ◽  
R Edwards ◽  
F Sharp ◽  
W J Rutter
Keyword(s):  
Nerve Growth Factor ◽  
Growth Factor ◽  
Postnatal Development ◽  
Sensory Deprivation ◽  
Nerve Growth ◽  
Growth Factor Gene ◽  
Gene Structure And Expression ◽  
The Brain ◽  
Different Tissues ◽  
Ngf Gene

The organization and biologically significant sequences of the entire mouse nerve growth factor (NGF) gene have been determined. The gene spans 45 kilobases and contains several small 5' exons. Transcription of the gene results in four different mRNA species, which can be accounted for by alternative splicing and independent initiation from two promoters. These transcripts encode proteins which have divergent N termini and the NGF moiety at their C termini. The levels of the various NGF transcripts have been determined in different tissues and throughout postnatal development. We have also examined the expression of these transcripts in the brain in response to specific early sensory deprivation. The results suggest that the expression of NGF mRNA during postnatal development is regulated independently of the formation of complex neural networks.

Oral administration of idebenone induces nerve growth factor in the brain and improves learning and memory in basal forebrain-lesioned rats

1994 ◽  
Vol 349 (4) ◽  
pp. 401-407 ◽  
Author(s):  
Atsumi Nitta ◽  
Yutaka Murakami ◽  
Yoshiko Furukawa ◽  
Wataru Kawatsura ◽  
Kyozo Hayashi ◽  
...  
Keyword(s):  
Nerve Growth Factor ◽  
Growth Factor ◽  
Oral Administration ◽  
Learning And Memory ◽  
Basal Forebrain ◽  
Nerve Growth ◽  
The Brain
Sign in / Sign up

Export Citation Format

Share Document