Functional characterization of a muscarinic receptor in the smooth muscle of the shark (Squalus acanthias) ventral aorta

Author(s):  
David H. Evans ◽  
Mark P. Gunderson
1999 ◽  
Vol 11 (12) ◽  
pp. 853-862 ◽  
Author(s):  
Chuen-Mao Yang ◽  
Yih-Jeng Tsai ◽  
Shiow-Lin Pan ◽  
Wen-Bin Wu ◽  
Chuan-Chwan Wang ◽  
...  

1991 ◽  
Vol 197 (1-2) ◽  
pp. 109-112 ◽  
Author(s):  
Ralph E. Howell ◽  
Keith Laemont ◽  
Raymond Gaudette ◽  
Maureen Raynor ◽  
Abby Warner ◽  
...  

2010 ◽  
Vol 25 (6) ◽  
pp. 595-604 ◽  
Author(s):  
Shiva Prasad Potta ◽  
Huamin Liang ◽  
Johannes Winkler ◽  
Michael Xavier Doss ◽  
Shuhua Chen ◽  
...  

2005 ◽  
Vol 2005 (3) ◽  
pp. 254-270 ◽  
Author(s):  
Kazem Zibara ◽  
Gwenaële Garin ◽  
John L. McGregor

Arterial smooth muscle cells (SMCs) play a major role in atherosclerosis and restenosis. Differential display was used to compare transcription profiles of synthetic SMCs to proliferating rat cultured SMC line. An isolated cDNA band (6A3-5) was shown by northern (7 kb) to be upregulated in the proliferating cell line. A rat tissue northern showed differential expression of this gene in different tissues. Using 5’ RACE and screening of a rat brain library, part of the cDNA was cloned and sequenced (5.4 kb). Sequence searches showed important similarities with a new family of transcription factors, bearing ARID motifs. A polyclonal antibody was raised and showed a protein band of 175 kd, which is localized intracellularly. We also showed that 6A3-5 is upregulated in dedifferentiated SMC (P9) in comparison to contractile SMC ex vivo (P0). This work describes cloning, structural, and functional characterization of a new early gene involved in SMC phenotype modulation.


2002 ◽  
Vol 14 (4) ◽  
pp. 271-282 ◽  
Author(s):  
A Giraldi ◽  
P Alm ◽  
V Werkström ◽  
L Myllymäki ◽  
G Wagner ◽  
...  

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