Hydrodynamics in Normal Pressure Hydrocephalus — Correlation Between the Incidence of B-Waves, Dynamics of Cerebrospinal Fluid Circulation, and Cerebral Blood Flow

1983 ◽  
pp. 669-674 ◽  
Author(s):  
N. Tamaki ◽  
T. Kusunoki ◽  
K. Fujita ◽  
S. Kose ◽  
S. Noda ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebrospinal Fluid ◽  
Cerebral Blood Flow ◽  
Normal Pressure Hydrocephalus ◽  
Normal Pressure ◽  
Fluid Circulation ◽  
Cerebrospinal Fluid Circulation

Normal pressure hydrocephalus

2019 ◽  
pp. 1083-1092
Author(s):  
Nicole Keong
Keyword(s):  
Blood Flow ◽  
Cerebrospinal Fluid ◽  
Cerebral Blood Flow ◽  
Fluid Flow ◽  
Surgical Management ◽  
Normal Pressure Hydrocephalus ◽  
Clinical Presentation ◽  
Normal Pressure ◽  
Cerebrospinal Fluid Flow ◽  
Underlying Mechanisms

This chapter is on normal pressure hydrocephalus (NPH) and deals with aspects from theories of pathogenesis, clinical presentation, and management, surgical management, and complications, as well as the assessment of outcome. It provides a concise overview of a challenging topic; many theories have been advanced to explain the underlying mechanisms by which the NPH syndrome develops. However, the basic pathophysiological processes still remain unclear. The major theory streams proposed for the pathogenesis of NPH can be loosely organized into structural, cerebral blood flow, and cerebrospinal fluid flow subgroups. The components of each theory stream are expanded in this chapter, although the list of studies supporting each section is by no means exhaustive.

scholarly journals Pattern of white matter regional cerebral blood flow and autoregulation in normal pressure hydrocephalus

Brain ◽  
2004 ◽  
Vol 127 (5) ◽  
pp. 965-972 ◽  
Author(s):  
Shahan Momjian ◽  
Brian K. Owler ◽  
Zofia Czosnyka ◽  
Marek Czosnyka ◽  
Alonso Pena ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
White Matter ◽  
Normal Pressure Hydrocephalus ◽  
Regional Cerebral Blood Flow ◽  
Normal Pressure ◽  
Regional Cerebral Blood

scholarly journals Pre-and postoperative cerebral blood flow changes in patients with idiopathic normal pressure hydrocephalus measured by computed tomography (CT)-perfusion

2016 ◽  
Vol 36 (10) ◽  
pp. 1755-1766 ◽  
Author(s):  
Doerthe Ziegelitz ◽  
Jonathan Arvidsson ◽  
Per Hellström ◽  
Mats Tullberg ◽  
Carsten Wikkelsø ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Normal Pressure Hydrocephalus ◽  
Normal Pressure ◽  
Idiopathic Normal Pressure Hydrocephalus ◽  
Lentiform Nucleus ◽  
Spatial Coverage ◽  
Potential Biomarker ◽  
Subcortical Regions

In idiopathic normal pressure hydrocephalus (iNPH), the cerebral blood flow (CBF) is of pathophysiological interest and a potential biomarker. Computed tomography perfusion (CTP), an established technique with high spatial resolution and quantitative measurements, has not yet been used in the iNPH context. If CTP were sensitive to the CBF levels and changes in iNPH, this technique might provide diagnostic and prognostic absolute perfusion thresholds. The aim of this work was to determine the applicability of CTP to iNPH. CBF measurements of 18 patients pre- and 17 three months postoperatively, and six healthy individuals (HI) were evaluated in 12 cortical and subcortical regions of interest. Correlations between CBF and symptomatology were analyzed in shunt-responders. Compared to HI, the preoperative CBF in iNPH was significantly reduced in normal appearing and periventricular white matter (PVWM), the lentiform nucleus and the global parenchyma. No CBF differences were shown between responders and non-responders. In responders, the CBF recovered postoperatively by 2.5–32% to approximately the level of HI, but remained significantly decreased in the PVWM of non-responders. The pre- and postoperative CBF of cortical and subcortical regions correlated with the intensity of symptoms. In spite of limited spatial coverage, CTP can measure CBF changes in iNPH.

scholarly journals Cerebral blood flow in normal pressure hydrocephalus.

Stroke ◽  
1987 ◽  
Vol 18 (6) ◽  
pp. 1074-1080 ◽  
Author(s):  
H L Mamo ◽  
P C Meric ◽  
J C Ponsin ◽  
A C Rey ◽  
A G Luft ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Normal Pressure Hydrocephalus ◽  
Normal Pressure

Cerebral Blood Flow and Autoregulation in Normal Pressure Hydrocephalus

Neurosurgery ◽  
1997 ◽  
Vol 40 (6) ◽  
pp. 1161-1167 ◽  
Author(s):  
Akira Tanaka ◽  
Masato Kimura ◽  
Yoshiya Nakayama ◽  
Shinya Yoshinaga ◽  
Masamichi Tomonaga
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Normal Pressure Hydrocephalus ◽  
Normal Pressure

scholarly journals Changes of Intracranial Pressure and Cerebral Blood Flow in Patients with Normal Pressure Hydrocephalus after Subarachnoid Hemorrhage

1981 ◽  
Vol 21 (4) ◽  
pp. 379-388 ◽  
Author(s):  
MINORU HAYASHI ◽  
HIDENORI KOBAYASHI ◽  
SHIGERU MUNEMOTO ◽  
SOTARO HIGASHI ◽  
JUN-ICHI NOZAKI ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Subarachnoid Hemorrhage ◽  
Intracranial Pressure ◽  
Normal Pressure Hydrocephalus ◽  
Normal Pressure

scholarly journals Changes in Cerebral Blood Flow during Cerebrospinal Fluid Pressure Manipulation in Patients with Normal Pressure Hydrocephalus: A Methodological Study

2004 ◽  
Vol 24 (5) ◽  
pp. 579-587 ◽  
Author(s):  
Brian K. Owler ◽  
Alonso Pena ◽  
Shahan Momjian ◽  
Zofia Czosnyka ◽  
Marek Czosnyka ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Normal Pressure Hydrocephalus ◽  
Fluid Pressure ◽  
Three Dimensional ◽  
Normal Pressure ◽  
Element Analysis ◽  
Csf Pressure ◽  
Arterial Blood ◽  
Positron Emission

The combination of cerebral blood flow measurement using 15O-water positron emission tomography with magnetic resonance coregistration and CSF infusion studies was used to study the global and regional changes in CBF with changes in CSF pressure in 15 patients with normal pressure hydrocephalus. With increases in CSF pressure, there was a variable increase in arterial blood pressure between individuals and global CBF was reduced, including in the cerebellum. Regionally, mean CBF decreased in the thalamus and basal ganglia, as well as in white matter regions. These reductions in CBF were significantly correlated with changes in the CSF pressure and with proximity to the ventricles. A three-dimensional finite-element analysis was used to analyze the effects on ventricular size and the distribution of stress during infusion. To study regional cerebral autoregulation in patients with possible normal pressure hydrocephalus, a sensitive CBF technique is required that provides absolute, not relative normalized, values for regional CBF and an adequate change in cerebral perfusion pressure must be provoked.

scholarly journals Regional cerebral blood flow in normal pressure hydrocephalus.

1987 ◽  
Vol 50 (12) ◽  
pp. 1589-1596 ◽  
Author(s):  
N R Graff-Radford ◽  
K Rezai ◽  
J C Godersky ◽  
P Eslinger ◽  
H Damasio ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Normal Pressure Hydrocephalus ◽  
Regional Cerebral Blood Flow ◽  
Normal Pressure ◽  
Regional Cerebral Blood
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