The Role of Specific Antibodies of Different Immunoglobulin Classes in the Rapid Diagnosis of Systemic Mycotic Infections

1985 ◽  
pp. 162-168
Author(s):  
L. Kaufman
Keyword(s):  
Rapid Diagnosis ◽  
Specific Antibodies ◽  
Mycotic Infections

scholarly journals Iatrogenic bacterial meningitis: an unmasked threat

CJEM ◽  
2012 ◽  
Vol 14 (04) ◽  
pp. 263-266 ◽  
Author(s):  
Robert Barnwell ◽  
Vincent Ball
Keyword(s):  
Emergency Department ◽  
Bacterial Meningitis ◽  
Spinal Anesthesia ◽  
Lumbar Puncture ◽  
Epidural Anesthesia ◽  
Emergency Physician ◽  
Rapid Diagnosis ◽  
Treatment And Prevention ◽  
Sterile Technique

ABSTRACT Iatrogenic bacterial meningitis (IBM) is a rare but serious complication of neuraxial procedures, such as spinal and epidural anesthesia or lumbar puncture. We report a case of a 46-year-old female who presented to the emergency department with bacterial meningitis after spinal anesthesia. We reviewthe existing literature outlining the pathogenesis, vector hypothesis, diagnosis, treatment, and prevention as they relate to IBM. We highlight the role of the emergency physician in the rapid diagnosis of this disease, and underscore the need for sterile technique when performing lumbar punctures.

Mixed cryoglobulinemia: the role of HCV and organ-specific antibodies

1996 ◽  
pp. 283-293
Author(s):  
S. Bombardieri ◽  
A. Tavoni ◽  
M. Mosca ◽  
L. La Civita ◽  
M. P. Dolcher ◽  
...  
Keyword(s):  
Mixed Cryoglobulinemia ◽  
Specific Antibodies ◽  
Organ Specific

scholarly journals PRP4: a protein of the yeast U4/U6 small nuclear ribonucleoprotein particle

1989 ◽  
Vol 9 (9) ◽  
pp. 3710-3719
Author(s):  
J Banroques ◽  
J N Abelson
Keyword(s):  
Essential Role ◽  
Mrna Splicing ◽  
Ribonucleoprotein Particle ◽  
Specific Antibodies ◽  
Small Nuclear Ribonucleoprotein ◽  
Assembly Pathway ◽  
Nuclear Ribonucleoprotein ◽  
Small Nuclear Ribonucleoprotein Particle

The Saccharomyces cerevisiae prp mutants (prp2 through prp11) are known to be defective in pre-mRNA splicing at nonpermissive temperatures. We have sequenced the PRP4 gene and shown that it encodes a 52-kilodalton protein. We obtained PRP4 protein-specific antibodies and found that they inhibited in vitro pre-mRNA splicing, which confirms the essential role of PRP4 in splicing. Moreover, we found that PRP4 is required early in the spliceosome assembly pathway. Immunoprecipitation experiments with anti-PRP4 antibodies were used to demonstrate that PRP4 is a protein of the U4/U6 small nuclear ribonucleoprotein particle (snRNP). Furthermore, the U5 snRNP could be immunoprecipitated through snRNP-snRNP interactions in the large U4/U5/U6 complex.

Examination of the role of Mycoplasma bovis in bovine pneumonia and a mathematical model for its evaluation

2004 ◽  
Vol 52 (4) ◽  
pp. 445-456 ◽  
Author(s):  
M. Tenk ◽  
L. Stipkovits ◽  
L. Hufnagel
Keyword(s):  
Mathematical Model ◽  
Probability Model ◽  
Mycoplasma Bovis ◽  
Seropositivity Rate ◽  
Lung Lesions ◽  
Specific Antibodies ◽  
Cattle Herds ◽  
The Relationship

The authors screened 34 large cattle herds for the presence of Mycoplasma bovis infection by examining slaughtered cattle for macroscopic lung lesions, by culturing M. bovis from lung lesions and at the same time by testing sera for the presence of antibodies against M. bovis. Among the 595 cattle examined, 33.9% had pneumonic lesions, mycoplasmas were isolated from 59.9% of pneumonic lung samples, and 10.9% of sera from those animals contained antibodiesto M. bovis. In 25.2% of the cases M. bovis was isolated from lungs with no macroscopic lesions. The proportion of seropositive herds was 64.7%. The average seropositivity rate of individuals was 11.3% but in certain herds it exceeded 50%. A probability model was developed for examining the relationship among the occurrence of pneumonia, the isolation of M. bovis from the lungs and the presence of M. bovis specific antibodies in sera.

scholarly journals The role of endothelial filtration for locoregional targeting of hepatic tumours with endothelium-specific antibodies and nanoparticles

2018 ◽  
Vol 29 ◽  
pp. v5
Author(s):  
N. Winkler ◽  
F. Strübing ◽  
D. Kyuno ◽  
B. Qian ◽  
Z. Wang ◽  
...  
Keyword(s):  
Specific Antibodies ◽  
Hepatic Tumours

scholarly journals Rapid Diagnosis of Blood Stream Infections in ICU: Recent Advances

2019 ◽  
Vol 2 (1) ◽  
pp. 177-180
Author(s):  
Raju Prasad Pangeni
Keyword(s):  
Intensive Care ◽  
Diagnostic Tests ◽  
Rapid Detection ◽  
Blood Stream ◽  
Turnover Time ◽  
Rapid Diagnosis ◽  
Molecular Techniques ◽  
Culture Methods ◽  
Blood Stream Infections

Blood stream infections and sepsis are major causes of hospitalization in most intensive care units around the globe, especially in developing countries like Nepal. Although the sepsis guidelines emphasize the role of early institution of appropriate antibiotics, it is practically challenging due to delayed turnover time of currently available diagnostic tests. Modifications in traditional blood culture methods, use of molecular techniques and availability of biomarkers have raised hope in rapid detection of blood stream infections.

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