Enzyme Induction: Its Relevance for Internal Exposure and Health Risks

1988 ◽  
pp. 76-83
Author(s):  
B. Koimodin-Hedman
Keyword(s):  
Health Risks ◽  
Enzyme Induction ◽  
Internal Exposure

scholarly journals Biomonitoring and Subsequent Risk Assessment of Combined Exposure to Phthalates in Iranian Children and Adolescents

2018 ◽  
Vol 15 (11) ◽  
pp. 2336 ◽  
Author(s):  
Maryam Zare Jeddi ◽  
Mohamad Eshaghi Gorji ◽  
Ivonne Rietjens ◽  
Jochem Louisse ◽  
Yuri Bruinen de Bruin ◽  
...  
Keyword(s):  
Risk Assessment ◽  
Children And Adolescents ◽  
Health Risks ◽  
Safety Concern ◽  
Hazard Quotient ◽  
Daily Intake ◽  
Hazard Index ◽  
Internal Exposure ◽  
Combined Exposure ◽  
Iranian Children

This study aimed to estimate the exposure and related health risks of phthalates, and to assess the health risks from combined exposure to three of the phthalates sharing the same mode of action (anti-androgenicity) in children. We determined the internal exposure of 56 Iranian children and adolescents aged 6 to 18 years by analyzing seven urinary metabolites of five phthalates. The estimated daily intake values derived from the biomonitoring data ranged from 0.01 µg/kg bw/day for butyl benzyl phthalate (BBP), to 17.85 µg/kg bw/day for di(2-ethylhexyl) phthalate (DEHP). The risk assessment revealed that not only the exposure to the individual phthalates, but also the combined exposure to the three anti-androgenic phthalates (DEHP, DBP, BBP) did not raise a safety concern (hazard index values averaged 0.2). The range of maximum cumulative ratio values varied from around 1 for most individuals to around 2 in some individuals, indicating that the combined exposures were dominated by one and in some cases by two of the three anti-androgenic phthalates, especially dibutyl phthalate (DBP) and/or DEHP. Based on biomonitoring data, the overall combined exposure of Iranian children to phthalates does not raise a concern, while reduction of exposure is best focused on DEHP and DBP that showed the highest hazard quotient.

A critical review on human internal exposure of phthalate metabolites and the associated health risks

2021 ◽  
pp. 116941
Author(s):  
Senyuan Huang ◽  
Zenghua Qi ◽  
Shengtao Ma ◽  
Guiying Li ◽  
Chaoyang Long ◽  
...  
Keyword(s):  
Health Risks ◽  
Critical Review ◽  
Internal Exposure ◽  
Phthalate Metabolites

scholarly journals The internal exposure of phthalate metabolites and bisphenols in waste incineration plant workers and the associated health risks

2020 ◽  
Vol 145 ◽  
pp. 106101 ◽  
Author(s):  
Shaoyou Lu ◽  
Dongfeng Yang ◽  
Xiang Ge ◽  
Le Li ◽  
Yang Zhao ◽  
...  
Keyword(s):  
Health Risks ◽  
Waste Incineration ◽  
Internal Exposure ◽  
Incineration Plant ◽  
Phthalate Metabolites

Eczematous dermatitis caused by internal exposure to copper

1972 ◽  
Vol 106 (3) ◽  
pp. 386-387 ◽  
Author(s):  
V. P. Barranco
Keyword(s):  
Internal Exposure ◽  
Eczematous Dermatitis

Host enzyme induction of bacterial infection

1968 ◽  
Vol 121 (1) ◽  
pp. 11-16 ◽  
Author(s):  
M. I. Rapoport
Keyword(s):  
Bacterial Infection ◽  
Enzyme Induction

The Globalization of Health: Risks, Responses, and Alternatives

2004 ◽  
Vol 3 (1/2) ◽  
pp. 245-269
Author(s):  
Richard L. Harris ◽  
Melinda J. Seid
Keyword(s):  
Health Risks

Hypoxic metabolism in wild rice (Zizania palustris): enzyme induction and metabolite production

1993 ◽  
Vol 89 (1) ◽  
pp. 165-171 ◽  
Author(s):  
Douglas G. Muench ◽  
O. William Archibold ◽  
Allen G. Good
Keyword(s):  
Enzyme Induction ◽  
Wild Rice ◽  
Metabolite Production ◽  
Zizania Palustris

Health Risks, Outcomes, and Globalization Issues With Women

PsycCRITIQUES ◽  
2006 ◽  
Vol 51 (30) ◽  
Author(s):  
Stephanie L. Brooke
Keyword(s):  
Health Risks
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