Regulatory, Structural and Biotechnological Aspects of The Aspergillus Nidulans Gene Cluster for Nitrate Assimilation

Author(s):  
J. R. Kinghorn ◽  
P. Montague ◽  
S. E. Unkles
1979 ◽  
Vol 34 (1) ◽  
pp. 19-32 ◽  
Author(s):  
A. Brian Tomsett ◽  
David J. Cove

SUMMARYThe genetic fine-structure of theniiAniaD gene region ofAspergillus nidulanshas been studied using deletion mapping. Deletions were identified asniiAniaD double mutants and comprised 1% of spontaneous chlorate-resistant mutants. All such double mutants were shown to involve deletions and their frequency was not increased by mutagenic treatment with eitherN-methyl-N′-nitro-N-nitrosoguanidine or with ultraviolet light. Deletion maps of theniaD andniiA genes have been constructed. A further class of mutation was also mapped using the deletions. Thesecrnmutations, which affect a gene whose function is as yet unknown, map on the centromere proximal side ofniiA. This analysis of a eukaryote gene cluster will provide a framework upon which to base studies of the regulation of the nitrate assimilation pathway.


Gene ◽  
1990 ◽  
Vol 90 (2) ◽  
pp. 181-192 ◽  
Author(s):  
I.L. Johnstone ◽  
P.C. McCabe ◽  
P. Greaves ◽  
S.J. Gurr ◽  
G.E. Cole ◽  
...  

Yeast ◽  
2006 ◽  
Vol 26 (2) ◽  
pp. 83-93 ◽  
Author(s):  
Erik Böer ◽  
Anja Schröter ◽  
Rüdiger Bode ◽  
Michael Piontek ◽  
Gotthard Kunze

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