A Potential Approach to Gene Therapy of Cancer

1992 ◽  
pp. 20-27
Author(s):  
Th. Friedmann
Keyword(s):  
Gene Therapy ◽  
Potential Approach

scholarly journals Gene Therapy Today and Tomorrow

Diseases ◽  
2019 ◽  
Vol 7 (2) ◽  
pp. 37 ◽  
Author(s):  
Kenneth Lundstrom
Keyword(s):  
Gene Therapy ◽  
Potential Approach ◽  
The Future

In the wake of a breakthrough in biotechnology providing realistic application of recombinant expressed proteins as drugs in the 1990s, gene therapy emerged as the potential approach for providing medicines of the future [...]

scholarly journals A Potential Approach for Gene Therapy Targeting Hepatoma Using a Liver-Specific Promoter on a Retroviral Vector.

1991 ◽  
Vol 16 (6) ◽  
pp. 503-510 ◽  
Author(s):  
Shigeki Kuriyama ◽  
Masahide Yoshikawa ◽  
Shigeaki Ishizaka ◽  
Tadasu Tsujii ◽  
Kazuhiro Ikenaka ◽  
...  
Keyword(s):  
Gene Therapy ◽  
Retroviral Vector ◽  
Potential Approach

scholarly journals Delivery Systems for Nucleic Acids and Proteins: Barriers, Cell Capture Pathways and Nanocarriers

Pharmaceutics ◽  
2021 ◽  
Vol 13 (3) ◽  
pp. 428
Author(s):  
Julian D. Torres-Vanegas ◽  
Juan C. Cruz ◽  
Luis H. Reyes
Keyword(s):  
Gene Therapy ◽  
Nucleic Acids ◽  
Genetic Diseases ◽  
Critical Factor ◽  
Cellular Internalization ◽  
Cell Capture ◽  
Inherited Disorders ◽  
Potential Approach ◽  
Efficient Delivery ◽  
Effective Delivery

Gene therapy has been used as a potential approach to address the diagnosis and treatment of genetic diseases and inherited disorders. In this line, non-viral systems have been exploited as promising alternatives for delivering therapeutic transgenes and proteins. In this review, we explored how biological barriers are effectively overcome by non-viral systems, usually nanoparticles, to reach an efficient delivery of cargoes. Furthermore, this review contributes to the understanding of several mechanisms of cellular internalization taken by nanoparticles. Because a critical factor for nanoparticles to do this relies on the ability to escape endosomes, researchers have dedicated much effort to address this issue using different nanocarriers. Here, we present an overview of the diversity of nanovehicles explored to reach an efficient and effective delivery of both nucleic acids and proteins. Finally, we introduced recent advances in the development of successful strategies to deliver cargoes.

Gene Therapy with Angiogenic Factors: A New Potential Approach to the Treatment of Ischemic Diseases

1997 ◽  
Vol 29 (9) ◽  
pp. 2311-2325 ◽  
Author(s):  
Jorge Safi Jr ◽  
Torsten R. Gloe ◽  
Teresa Riccioni ◽  
Imre Kovesdi ◽  
Maurizio C. Capogrossi
Keyword(s):  
Gene Therapy ◽  
Angiogenic Factors ◽  
Potential Approach ◽  
Ischemic Diseases

Antiangiogenic gene therapy delays growth of murine and human pancreatic adenocarcinoma in mice

2001 ◽  
Vol 120 (5) ◽  
pp. A349-A349
Author(s):  
J TSENG ◽  
F FARNEBO ◽  
O KISKER ◽  
C BECKER ◽  
C KUO ◽  
...  
Keyword(s):  
Gene Therapy ◽  
Pancreatic Adenocarcinoma ◽  
Human Pancreatic Adenocarcinoma

1107: Evaluation of Cystine Transport in Cultured Human Kidney Cells: Primer to Gene Therapy of Cystinuria

2005 ◽  
Vol 173 (4S) ◽  
pp. 300-300
Author(s):  
Sreedhar Sagi ◽  
Lutz Trojan ◽  
Peter Aiken ◽  
Maurice S. Michel ◽  
Thomas Knoll
Keyword(s):  
Gene Therapy ◽  
Human Kidney ◽  
Kidney Cells

790: Interleukin-2 Enhanced the Anti-Tumor Effect of Adenoviral-Mediated HSV-TK Gene Therapy in Murine Bladder Cancer Model

2005 ◽  
Vol 173 (4S) ◽  
pp. 214-214
Author(s):  
Shuji Terao ◽  
Toshiro Shirakawa ◽  
Kazumasa Goda ◽  
Sadao Kamidono ◽  
Akinobu Gotoh
Keyword(s):  
Gene Therapy ◽  
Bladder Cancer ◽  
Interleukin 2 ◽  
Cancer Model ◽  
Bladder Cancer Model
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