In a number of industrialized regions of the Russian Federation, even when using efficient high technologies in the manufacturing industry under the current linear economic model, especially in the context of pandemic (COVID-19) fails to implement the sustainable development goals in all of its ecological and economic requirements. This paper analyzes models and approaches to the implementation of the concept of renewable production and consumption in conditions of maximum use of resources, including those obtained by processing various types of waste. According to the analyzed one of the models, namely the circulation economic model, resources after consumption in the form of manufactured products and the resulting waste, suitable for processing into production resources, in the form of secondary. Within the framework of rational interaction of the industrially developed regions (Moscow and Kaluga), an experimental confirmation of the efficiency of waste processing of various types is given, by building an Ecotechnopark, implemented within the framework of public-private partnership, and obtaining secondary products. In the proposed circular economic model, resources after consumption in the form of production products are returned to production after processing. In addition, a possible indicator was identified and implemented that allows integrating traditional economic indicators into the "Green" gross national product (GNP), which is the sum of the natural capital of the region and its nominal GNP and is linked to the state of the ecosystem. Recommendations and conclusions on the performed studies are made.
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‐generating fusion protein systems