Behavioral Neurobiology of Psychedelic Drugs

Author(s):  
Jacob S. Aday ◽  
Alan K. Davis ◽  
Cayla M. Mitzkovitz ◽  
Emily K. Bloesch ◽  
Christopher C. Davoli

2021 ◽  
Vol 203 ◽  
pp. 173129
Author(s):  
M.L. Shawn Bates ◽  
Keith A. Trujillo
Keyword(s):  

1981 ◽  
Vol 10 (2) ◽  
pp. 47-50
Author(s):  
Geoffrey Rips

What was known in the United States as the ‘underground press’ – self-published newspapers of the youth counterculture sold at street corners and around campuses in American cities during the 1960s and early 70 s – was once a significant network estimated at over 400 publications. Their hallmark was opposition to US involvement in the Vietnam War, criticism of the authorities, of uncontrolled technology and big business, advocacy of sexual freedom and artistic experimentation and, frequently, the advocacy of marijuana, LSD and other psychedelic drugs. Few of these publications have survived the past ten years, and their disappearance has been variously attributed to the cooling of radical interest after the American withdrawal from Vietnam, as well as to the vague and shifting nature of the ‘hippie’ scene. Complaints by their publishers during the early and mid-seventies that printers refused their business, that office rents suddenly doubled, that advertising was cancelled, that papers were lost – these were seen as local accidents and were rarely reported by the established media. Claims of official or officially-sanctioned harassment were dismissed – even by fellow radicals – as paranoid. Recent research by Geoffrey Rips of the PEN American Center has revealed the extent and variety of official pressure exerted against alternative publications during the Vietnam War period. Using evidence from government hearings like the Church Committee, which reported in 1976, actual FBI documents released to American PEN under the Freedom of Information Act, and other sources, Mr Rips argues that such harassment contributed materially to the closure of certain publications and in general terms constituted a gross infringement on the protection afforded to dissenting opinion and to a free press under the US constitution. We publish edited extracts here from Geoffrey Rips' report which will be published in full by the PEN American Center and the City Lights Press.


1970 ◽  
Vol 11 (3) ◽  
pp. 207
Author(s):  
Sidney Cohen
Keyword(s):  

2017 ◽  
Vol 57 (5) ◽  
pp. 443-449
Author(s):  
Ralph Metzner

Whereas the terminology of psychedelics has acquired spurious cultural associations of “tripping,” the historically primal concept of consciousness expansion has two advantages. One, it connects psychedelic drugs with other modes of consciousness expansion, such as meditation and creative visioning; and two, it suggests contrasting comparison with the consciousness contraction involved in concentration and focus. Both expansions and contractions can be observed at the level of an individual’s states of consciousness and also at the level of the shared worldview of society. Contemporary world culture is moving toward an expanded worldview that recognizes both the material and the spiritual dimensions of our existence.


2021 ◽  
Author(s):  
Clara Rastelli ◽  
Antonino Greco ◽  
Yoed N. Kenett ◽  
Chiara Finocchiaro ◽  
Nicola De Pisapia

Historically, psychedelic drugs are known to modulate cognitive flexibility, a central aspect of cognition permitting adaptation to changing environmental demands. Despite proof suggesting phenomenological similarities between artificially-induced and actual psychedelic altered perception, experimental evidence is still lacking about whether the former is also able to modulate cognitive flexibility. To address this, we measure participants' cognitive flexibility through behavioral tasks after the exposure to virtual reality panoramic videos and their hallucinatory-like counterparts generated by the DeepDream algorithm. Results show that the estimated semantic network has a flexible structure when preceded by altered videos. Crucially, following the simulated psychedelic exposure, individuals also show an attenuated contribution of the automatic process and chaotic dynamics underlying the decision process. This suggests that simulated altered perceptual phenomenology enhances cognitive flexibility, presumably due to a reorganization in the cognitive dynamics that facilitates the exploration of uncommon decision strategies and inhibits automated choices.


1973 ◽  
Vol 37 (1) ◽  
pp. 227-232 ◽  
Author(s):  
Le Roy A. Stone ◽  
E. Robert Sinnett ◽  
Gary J. Coles

8 experienced users of “street-drugs” estimated the over-all similarity of 11 drug-substance combinations based on their own experiences with such combinations. Their similarity estimations were analyzed using multidimensional scaling procedures (namely, the Stone-Coles method). Four judgmental factor-dimensions were extracted and identified (tentative labels: I. Psychedelic drugs in combination with other substances vs pot in combination with downers; II. stimulant-depressant; III. psychedelic drugs vs other drugs, IV. LSD in combination with other substances) which accounted for 92% of the variance of the averaged similarity estimates. These particular judgmental factor-dimensions were similar to those extracted from judgments pertaining to single drugs as stimuli.


2017 ◽  
Vol 103 (4) ◽  
pp. 561-564 ◽  
Author(s):  
Edward M. Sellers ◽  
Deborah B. Leiderman
Keyword(s):  

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