Definition of Exercise-Induced Acute Renal Failure (ALPE)

1995 ◽  
Vol 5 (12) ◽  
pp. 2020-2023
Author(s):  
L R Sanders

Nonsteroidal anti-inflammatory drugs predispose to acute renal failure in conditions associated with decreased RBF. Such conditions include advanced age, hypertension, chronic renal insufficiency, diuretic use, and any condition decreasing effective circulating volume. Strenuous exercise also causes marked reductions in RBF. The patient discussed developed severe acute renal failure after strenuous exercise and therapeutic doses of ibuprofen and hydrochlorothiazide-triamterene. Urinalysis showed a nephritic sediment with red blood cell casts. Renal biopsy showed acute tubular necrosis and arteriolar nephrosclerosis. Although exercise-associated acute renal failure is uncommon, susceptible patients with exercise-induced renal ischemia and prostaglandin inhibition may develop this complication.


2005 ◽  
Vol 33 ◽  
pp. A82
Author(s):  
Jean-sebastien Rachoin ◽  
Walid Abou Assi ◽  
Christa Schorr ◽  
Barry Milcarek ◽  
Lawrence S Weisberg

2000 ◽  
Vol 15 (1) ◽  
pp. 104-106 ◽  
Author(s):  
Isao Kurihara ◽  
Jun Soma ◽  
Hiroshi Sato ◽  
Takayuki Ikarashi ◽  
Kazuo Tsunoda ◽  
...  

2012 ◽  
Vol 29 (2) ◽  
pp. 150 ◽  
Author(s):  
Ae Jin Kim ◽  
Soo Yong Park ◽  
Ji Yong Jung ◽  
Jae Hyun Chang ◽  
Hyun Hee Lee ◽  
...  

Author(s):  
Carrie A. Schinstock

The term acute kidney injury (AKI) has replaced acute renal failure in contemporary medical literature. AKI denotes a rapid deterioration of kidney function within hours to weeks, resulting in the accumulation of nitrogenous metabolites in addition to fluid, electrolyte, and acid-base imbalances. The definition of AKI was refined to a 3-stage definition, with criteria for stage 1 as follows: 1) an absolute increase in serum creatinine (SCr) by at least 0.3 mg/dL from baseline within 48 hours; or 2) a relative increase in SCr to at least 1.5 times baseline within the past 7 days; or 3) urine output decreased to less than 0.5 mL/kg/h for 6 hours.


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