Adaptive Mechanisms of Livestock to Changing Climate

Climate Change Impact on Livestock: Adaptation and Mitigation ◽

10.1007/978-81-322-2265-1_9 ◽

2015 ◽

pp. 123-138 ◽

Cited By ~ 1

Author(s):

V. P. Maurya ◽

Veerasamy Sejian ◽

Mahesh Gupta ◽

S. S. Dangi ◽

Ankita Kushwaha ◽

...

Keyword(s):

Changing Climate ◽

Adaptive Mechanisms

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A multi-country analysis on potential adaptive mechanisms to cold and heat in a changing climate

Environment International ◽

10.1016/j.envint.2017.11.006 ◽

2018 ◽

Vol 111 ◽

pp. 239-246 ◽

Cited By ~ 45

Author(s):

Ana M. Vicedo-Cabrera ◽

Francesco Sera ◽

Yuming Guo ◽

Yeonseung Chung ◽

Katherine Arbuthnott ◽

...

Keyword(s):

Changing Climate ◽

Adaptive Mechanisms ◽

Country Analysis

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Vascular adaptations to hypoxia: molecular and cellular mechanisms regulating vascular tone

Essays in Biochemistry ◽

10.1042/bse0430105 ◽

2007 ◽

Vol 43 ◽

pp. 105-120 ◽

Cited By ~ 8

Author(s):

Michael L. Paffett ◽

Benjimen R. Walker

Keyword(s):

Vascular Tone ◽

Cellular Proliferation ◽

Hypoxic Pulmonary Vasoconstriction ◽

Hypoxia Inducible Factor ◽

Systemic Circulation ◽

Cellular Mechanisms ◽

Hypoxia Inducible Factor 1 ◽

Pulmonary Vasoconstriction ◽

Adaptive Mechanisms ◽

Adaptive Processes

Several molecular and cellular adaptive mechanisms to hypoxia exist within the vasculature. Many of these processes involve oxygen sensing which is transduced into mediators of vasoconstriction in the pulmonary circulation and vasodilation in the systemic circulation. A variety of oxygen-responsive pathways, such as HIF (hypoxia-inducible factor)-1 and HOs (haem oxygenases), contribute to the overall adaptive process during hypoxia and are currently an area of intense research. Generation of ROS (reactive oxygen species) may also differentially regulate vascular tone in these circulations. Potential candidates underlying the divergent responses between the systemic and pulmonary circulations may include Nox (NADPH oxidase)-derived ROS and mitochondrial-derived ROS. In addition to alterations in ROS production governing vascular tone in the hypoxic setting, other vascular adaptations are likely to be involved. HPV (hypoxic pulmonary vasoconstriction) and CH (chronic hypoxia)-induced alterations in cellular proliferation, ionic conductances and changes in the contractile apparatus sensitivity to calcium, all occur as adaptive processes within the vasculature.

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