An Interactive Freehand ROI Tool for Thyroid Uptake Studies Using Gamma Camera

2016 ◽  
pp. 349-355
Author(s):  
Palla Sri Harsha ◽  
A. Shiva ◽  
Kumar T. Rajamani ◽  
Siva Subramanyam ◽  
Siva Sankar Sai
Keyword(s):  
Gamma Camera ◽  
Thyroid Uptake ◽  
Uptake Studies

Development of an Interactive GUI Tool for Thyroid Uptake Studies using Gamma Camera

2016 ◽  
Vol 5 (1) ◽  
pp. 1-8
Author(s):  
Amruthavakkula Shiva ◽  
Vignesh T. Sai ◽  
Subramaniyan V. Siva ◽  
Kumar T. Rajamani ◽  
Sankara Sai S. Siva
Keyword(s):  
Gamma Camera ◽  
Region Of Interest ◽  
Software Tool ◽  
Blood Stream ◽  
Tracer Uptake ◽  
Thyroid Uptake ◽  
Iodine 131 ◽  
Left And Right ◽  
Uptake Studies

Thyroid uptake study is a technique that requires injection of a radio-isotope/radiotracer emitting gamma rays into the blood stream of the patient to study the functionality of thyroid in accordance to its uptake. The Gamma Camera uses a LEAP (Low Energy All Purpose) collimator which handles only photons emitted from radio-isotopes having lower emission energies. Technetium-99m is used whose energy of emission is around 140 keV. For a typical Thyroid Uptake Probe where Iodine-131 having greater emission energy of 364 keV is preferred, but existing Thyroid Uptake software is not feasible. Therefore an Interactive GUI (Graphical User Interface) tool was developed using Fiji for determination of tracer uptake by manually drawing the Region of Interest around left and right thyroid lobes separately. Developed tool was tested on 35 real time thyroid cases and the uptake values obtained are compared with those obtained from the existing software tool.

Comparative Thyroid Uptake Studies with131I and99mTcO4−

1972 ◽  
Vol 34 (4) ◽  
pp. 630-637 ◽  
Author(s):  
G. BURKE ◽  
A. HALKO ◽  
G. E. SILVERSTEIN ◽  
M. HILLIGOSS
Keyword(s):  
Thyroid Uptake ◽  
Uptake Studies

Comparison of Tc-99m Pertechnetate Thyroid Uptake Rates by Gamma Probe and Gamma Camera Methods for Differentiating Graves’ Disease and Thyroiditis

2021 ◽  
Author(s):  
Meihua Jin ◽  
Jonghwa Ahn ◽  
Seong-gil Jo ◽  
Jangwon Park ◽  
Min Ji Jeon ◽  
...  
Keyword(s):  
Diagnostic Accuracy ◽  
Uptake Rate ◽  
Gamma Camera ◽  
Gamma Probe ◽  
Probe Method ◽  
Graves Disease ◽  
Reference Ranges ◽  
Cutoff Value ◽  
Uptake Rates ◽  
Thyroid Uptake

Abstract Although technetium-99m (99mTc) pertechnetate thyroid uptake rate can be measured by gamma camera with scintigraphy as well as by gamma probe, the normal reference range known as quite different between them. This study was performed to compare their diagnostic accuracy for evaluating patients with hyperthyroidism. We retrospectively reviewed consecutive 371 patients (euthyroid 89, Graves 167, and thyroiditis 115) who had simultaneously measured data of thyroid uptake rates by both gamma probe and camera methods in our hospital from November 2019 to June 2020. The reference ranges in euthyroid patients were 2.0-4.7% and 0.3–1.9% for probe and camera methods, respectively. For differentiating Graves’ disease and thyroiditis, the area under the curve of the camera method was significantly greater than that of the probe method (0.988 vs 0.975, p = 0.030) on receiver operating characteristic curve analysis. With a cutoff value of 0.7%, the sensitivity and specificity for the camera method were 93.4% and 94.8%, respectively. With a cutoff value of 3.0%, those for the probe method were 92.2% and 91.3%, respectively. In conclusion, 99mTc pertechnetate thyroid uptake rate measured by the camera method with scintigraphy had higher diagnostic accuracy than the probe method for evaluating patients with hyperthyroidism.

Diagnostic Value of 20 Minute 99mTc Pertechnetate Thyroid Uptake

1971 ◽  
Vol 10 (04) ◽  
pp. 305-315
Author(s):  
T. M. D. Gimlette ◽  
R. Höschl
Keyword(s):  
Gamma Camera ◽  
Processing System ◽  
Nuclear Data ◽  
Close Correlation ◽  
Diagnostic Value ◽  
Computer Assisted ◽  
Computer Technique ◽  
99Mtc Pertechnetate ◽  
Thyroid Uptake ◽  
Stimulation Tests

SummaryFour hour thyroid uptake of orally administered radioiodine was compared with 20 minute uptake of intravenously given 99mTc pertechnetate in 170 patients.Pertechnetate uptake was estimated by counting dots on a rectilinear scan, with appropriate background subtraction. In 22 patients the dot counting method was compared with computer assisted processing of a gamma camera image, using Nuclear Data 50/50 MED Digital Image Processing System. There was good correlation between the two methods, the computer technique is faster and easier, but does not provide, at the same time, a very satisfactory thyroid scan.Optimum interval for measurement of pertechnetate thyroid uptake with the rectilinear scanner is 20—30 minutes after the intravenous dose. When the computer assisted gamma camera can be employed the 10 minute interval would probably be more suitable for differentiation between euthyroid and hyperthyroid patients.For diagnostic accuracy the radioiodine and pertechnetate methods were identical (87% correct), there was quite close correlation between them and both were suitable for T3 suppression and TSH stimulation tests. The pertechnetate method is quicker to complete and provides a scan of the thyroid, but it requires an intravenous injection and is more demanding in personnel and equipment.

scholarly journals Thyroid Uptake Error in Four Different Gamma Camera Systems

2004 ◽  
Vol 60 (3) ◽  
pp. 387-392
Author(s):  
AI YOSHIDA ◽  
KYOKO SAITO ◽  
YOSHIMUNE ENDO ◽  
KAZUAKI MORI ◽  
MISAYO SEKI ◽  
...  
Keyword(s):  
Gamma Camera ◽  
Camera Systems ◽  
Thyroid Uptake
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