Bacterial Degradation of Polychlorinated Biphenyls

2010 ◽  
pp. 347-366 ◽  
Author(s):  
Martina Mackova ◽  
Ondrej Uhlik ◽  
Petra Lovecka ◽  
Jitka Viktorova ◽  
Martina Novakova ◽  
...  
Keyword(s):  
Polychlorinated Biphenyls ◽  
Bacterial Degradation

scholarly journals Bacterial degradation of a mixture of hydroxy- and metoxypolychlorinated biphenyls

2019 ◽  
Vol 486 (3) ◽  
pp. 307-311
Author(s):  
D. O. Egorova ◽  
T. I. Gorbunova ◽  
M. G. Pervova ◽  
K. A. Plotnikova ◽  
T. D. Kiryanova ◽  
...  
Keyword(s):  
Polychlorinated Biphenyls ◽  
Total Content ◽  
Bacterial Degradation ◽  
Specific Rate ◽  
Bacterial Transformation ◽  
Initial Concentration ◽  
Chemical Functionalization ◽  
Pcb Congeners ◽  
Total Absence ◽  
Rhodococcus Wratislaviensis

In this work, the possibility of combining the methods of chemical functionalization of a mixture of polychlorinated biphenyls before the formation of a mixture of hydroxy- and methoxy-chlorinated biphenyls and the bacterial transformation of the compounds obtained with the aim of their utilization was investigated. As a result of a 100% conversion, a mixture of compounds identified as methoxy- (30 compounds), hydroxy- (44 compounds) and methoxy (hydroxy) derivatives (47 compounds) was obtained by reacting a mixture of Sovol with MeONa in MeOH and DMSO. PCB congeners. The total content of all hydroxy derivatives was 77.2%. It was established that the strain Rhodococcus wratislaviensis KT112-7 carries out the destruction of 73-93% of this mixture at the initial concentration of 0.25-1.50 g/l. The best result was obtained with a decomposition of 0.1 g/l of a mixture of methoxy- and hydroxy-polychlorobiphenyls (on the 10th day the total absence of the starting compounds). The specific rate of destruction was in direct correlation with the initial concentration of the mixture. It has been shown that during bacterial transformation there is no accumulation of toxic intermediate compounds.

Bacterial Degradation of a Mixture of Hydroxy and Methoxy Polychlorinated Biphenyls

2019 ◽  
Vol 486 (1) ◽  
pp. 133-136
Author(s):  
D. O. Egorova ◽  
T. I. Gorbunova ◽  
M. G. Pervova ◽  
K. A. Plotnikova ◽  
T. D. Kiryanova ◽  
...  
Keyword(s):  
Polychlorinated Biphenyls ◽  
Bacterial Degradation

Pesticide and non-dioxin-like polychlorinated biphenyls (NDL-PCBs) residues in foodstuffs from Ismailia city, Egypt

2008 ◽  
pp. 1-9 ◽  
Author(s):  
N. Loutfy ◽  
M. Fuerhacker ◽  
C. Lesueur ◽  
M. Gartner ◽  
M. Tawfic Ahmed ◽  
...  
Keyword(s):  
Polychlorinated Biphenyls

Fatty Liver and Impaired Hepatic Metabolism Alters the Congener-Specific Distribution of Polychlorinated Biphenyls (PCBs) in Mice with a Liver-Specific Deletion of Cytochrome P450 Reductase

2020 ◽  
Author(s):  
Xueshu Li ◽  
Chun-Yun Zhang ◽  
Hans-Joachim Lehmler
Keyword(s):  
Cytochrome P450 ◽  
Polychlorinated Biphenyls ◽  
Fatty Liver ◽  
Partition Coefficients ◽  
Hepatic Metabolism ◽  
Gas Chromatography Mass Spectrometry ◽  
Cytochrome P450 Reductase ◽  
P450 Reductase ◽  
Specific Distribution ◽  
Specific Deletion

Polychlorinated biphenyls (PCBs) are persistent organic pollutants that are linked to adverse health outcomes. PCB tissue levels are determinants of PCB toxicity; however, it is unclear how factors, such as an altered metabolism and/or a fatty liver, affect PCB distribution in vivo. We determined the congener-specific disposition of PCBs in mice with a liver specific deletion of cytochrome P450 reductase (KO), a model of fatty liver with impaired hepatic metabolism, and wildtype (WT) mice. Male and female KO and WT mice were exposed orally to Aroclor 1254, a technical PCB mixture. PCBs were quantified in adipose, blood, brain and liver tissues by gas chromatography-mass spectrometry. PCB profiles and levels in tissues were genotype and sex dependent. PCB levels were higher in the liver from KO compared to WT mice. PCB profiles showed clear differences between tissues from the same exposure group. While experimental tissue : blood partition coefficients in KO and WT mice did not follow the trends predicted using a composition-based model, the agreement between experimental and calculated partition coefficients was still reasonable. Thus, a fatty liver and/or an impaired hepatic metabolism alter the distribution of PCBs in mice and the magnitude of the partitioning of PCBs from blood into tissues can be approximated using composition-based models.<br>

Determination of Polychlorinated Biphenyls (PCB) in Insulating Fluids

2017 ◽  
Vol 83 (11) ◽  
pp. 15-20
Author(s):  
E. S. Brodskii ◽  
◽  
A. A. Shelepchikov ◽  
G. A. Kalinkevich ◽  
E. Ya. Mir-Kadyrova ◽  
...  
Keyword(s):  
Polychlorinated Biphenyls
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