High-Grade Brain Tumours: Evaluation of New Brain Lesions by Amino Acid PET

2011 ◽  
pp. 111-117
Author(s):  
Robert Pichler ◽  
Sabine Spiegl-Kreinecker ◽  
Gabriele Wurm
Keyword(s):  
Amino Acid ◽  
Brain Tumours ◽  
Brain Lesions ◽  
High Grade ◽  
Amino Acid Pet

Amino acid PET for brain tumours — ready for the clinic?

2016 ◽  
Vol 12 (7) ◽  
pp. 375-376 ◽  
Author(s):  
Karl-Josef Langen ◽  
Colin Watts
Keyword(s):  
Amino Acid ◽  
Brain Tumours ◽  
Amino Acid Pet

scholarly journals Amino acid PET and MR perfusion imaging in brain tumours

2017 ◽  
Vol 5 (3) ◽  
pp. 209-223 ◽  
Author(s):  
Christian P. Filss ◽  
Francesco Cicone ◽  
Nadim Jon Shah ◽  
Norbert Galldiks ◽  
Karl-Josef Langen
Keyword(s):  
Amino Acid ◽  
Perfusion Imaging ◽  
Brain Tumours ◽  
Mr Perfusion ◽  
Mr Perfusion Imaging ◽  
Amino Acid Pet

scholarly journals Hybrid MR-PET of brain tumours using amino acid PET and chemical exchange saturation transfer MRI

2018 ◽  
Vol 45 (6) ◽  
pp. 1031-1040 ◽  
Author(s):  
N. A. da Silva ◽  
P. Lohmann ◽  
J. Fairney ◽  
A. W. Magill ◽  
A.-M. Oros Peusquens ◽  
...  
Keyword(s):  
Amino Acid ◽  
Brain Tumours ◽  
Chemical Exchange ◽  
Chemical Exchange Saturation Transfer ◽  
Saturation Transfer ◽  
Amino Acid Pet

scholarly journals Update on amino acid PET of brain tumours

2018 ◽  
Vol 31 (4) ◽  
pp. 354-361 ◽  
Author(s):  
Karl-Josef Langen ◽  
Norbert Galldiks
Keyword(s):  
Amino Acid ◽  
Brain Tumours ◽  
Amino Acid Pet

scholarly journals A systematic review of the utility of amino acid PET in assessing treatment response to bevacizumab in recurrent high-grade glioma

2021 ◽  
Author(s):  
Kendall L Hughes ◽  
Christen M O’Neal ◽  
Bethany J Andrews ◽  
Alison M Westrup ◽  
James D Battiste ◽  
...  
Keyword(s):  
Systematic Review ◽  
Amino Acid ◽  
High Grade Glioma ◽  
High Grade ◽  
Inclusion Criteria ◽  
Early Treatment Failure ◽  
Search Terms ◽  
Amino Acid Pet ◽  
Improving Accuracy ◽  
Induced Changes

Abstract Currently, bevacizumab (BEV), an antiangiogenic agent, is used as an adjunctive therapy to re-irradiation and surgery in patients with recurrent high-grade gliomas (rHGG). BEV has shown to decrease enhancement on MRI, but it is often unclear if these changes are due to tumor response to BEV or treatment-induced changes in the blood brain barrier. Preliminary studies show that amino acid PET can aid in distinguishing these changes on MRI.The authors performed a systematic review of PubMed and Embase through July 2020 with the search terms ‘bevacizumab’ or ‘Avastin’ and ‘recurrent glioma’ and ‘PET,’ yielding 38 papers, with 14 meeting inclusion criteria. Thirteen out of fourteen studies included in this review used static PET and three studies used dynamic PET to evaluate the use of BEV in rHGG. Six studies used the amino acid tracer [ 18F]FET, four studies used [ 11C]MET, and four studies used [ 18F]FDOPA. [ 18F]FET, [ 11C]MET, and [ 18F]FDOPA PET in combination with MRI have shown promising results for improving accuracy in diagnosing tumor recurrence, detecting early treatment failure, and distinguishing between tumor progression and treatment-induced changes in patients with rHGG treated with BEV.

Non-invasive grading of brain tumours using dynamic amino acid PET imaging : does it work for 11C-Methionine?

2007 ◽  
Vol 34 (12) ◽  
pp. 2082-2087 ◽  
Author(s):  
Gérard Moulin-Romsée ◽  
Eduard D’Hondt ◽  
Tjibbe de Groot ◽  
Jan Goffin ◽  
Raf Sciot ◽  
...  
Keyword(s):  
Amino Acid ◽  
Pet Imaging ◽  
Brain Tumours ◽  
Non Invasive ◽  
Amino Acid Pet
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