Search for a Primate Model of Human Sleep-Related Hormone Secretion

1981 ◽  
pp. 42-67
Author(s):  
H.-J. Quabbe
Keyword(s):  
Hormone Secretion ◽  
Primate Model ◽  
Human Sleep

scholarly journals Modafinil and γ-hydroxybutyrate have sleep state-specific pharmacological actions on hypocretin-1 physiology in a primate model of human sleep

2009 ◽  
Vol 20 (7) ◽  
pp. 643-652 ◽  
Author(s):  
Jamie M. Zeitzer ◽  
Christine L. Buckmaster ◽  
Hans-Peter Landolt ◽  
David M. Lyons ◽  
Emmanuel Mignot
Keyword(s):  
Sleep State ◽  
Primate Model ◽  
Human Sleep ◽  
Hypocretin 1

Hexachlorobenzene toxicity in the monkey ovary: III. Ultrastructure induced by high (10 mg/kg) dose exposure

1991 ◽  
Vol 49 ◽  
pp. 130-131
Author(s):  
A. Singh ◽  
A. Dykeman ◽  
J. Jarrelf ◽  
D. C. Villeneuve
Keyword(s):  
Present Report ◽  
Reproductive Toxicity ◽  
Control Group ◽  
Primate Model ◽  
Human Follicular Fluid ◽  
Thin Sections ◽  
Cynomolgus Monkeys ◽  
Cacodylate Buffer ◽  
Induction Cycle ◽  
Comprehensive Study

Hexachlorobenzene (HCB), a persistent and mobile organochlorine pesticide, occurs in environment. HCB has been shown to be present in human follicular fluid. An objective of the present report, which is part of a comprehensive study on reproductive toxicity of HCB, was to determine the cytologic effects of the compound on ovarian follicles in a primate model.Materials and Methods. Eight Cynomolgus monkeys were housed under controlled conditions at Animal facility of Health and Welfare, Ottawa. Animals were orally administered gelatin capsules containing HCB mixed with glucose in daily dosages of 0.0 or 10 mg/kg b.w. for 90 days; the former was the control group. On the menstrual period following completion of dosing, the monkeys underwent an induction cycle of superovulation. At necropsy, one-half of an ovary from each animal was diced into ca. 2- to 3-mm cubed specimens that were fixed by immersion in 2.5% glutaraldehyde in 0.1 M cacodylate buffer (pH 7.3). Subsequent procedures followed to obtain thin sections that were examined in a Hitachi H-7000 electron microscope have been described earlier.

Changes in the CEA gene are a basis for the lack of hepatic metastases in a spontaneous colorectal cancer primate model

2001 ◽  
Vol 120 (5) ◽  
pp. A167-A167
Author(s):  
R ZIMMER ◽  
P THOMAS ◽  
N CLAPP ◽  
C STANNERS ◽  
M TOBI ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Hepatic Metastases ◽  
Primate Model ◽  
Cea Gene

Methods for assessing human sleep

1971 ◽  
Vol 127 (3) ◽  
pp. 484a-492
Author(s):  
M. W. Johns
Keyword(s):  
Human Sleep
Sign in / Sign up

Export Citation Format

Share Document