Oral Contraceptives and Breast Disease

1991 ◽  
pp. 73-95
Author(s):  
Kathryn F. McGonigle ◽  
George R. Huggins
Keyword(s):  
Oral Contraceptives ◽  
Breast Disease

Oral contraceptives and breast disease in premenopausal northern albertan women

1978 ◽  
Vol 22 (6) ◽  
pp. 700-707 ◽  
Author(s):  
Alan W. Lees ◽  
Patricia E. Burns ◽  
Michael Grace
Keyword(s):  
Oral Contraceptives ◽  
Breast Disease

ORAL CONTRACEPTIVES AND BREAST DISEASE

1978 ◽  
Vol 107 (3) ◽  
pp. 236-244 ◽  
Author(s):  
JENNIFER L. KELSEY ◽  
THEODORE R. HOLFORD ◽  
COLIN WHITE ◽  
EUGENE S. MAYER ◽  
STANLEY E. KILTY ◽  
...  
Keyword(s):  
Oral Contraceptives ◽  
Breast Disease

Oral contraceptives and breast disease

1991 ◽  
Vol 56 (5) ◽  
pp. 799-819 ◽  
Author(s):  
Edward E. Wallach ◽  
Kathryn F. McGonigle ◽  
George R. Huggins
Keyword(s):  
Oral Contraceptives ◽  
Breast Disease

Oral contraceptives and benign breast disease: A case-control study

1984 ◽  
Vol 149 (6) ◽  
pp. 602-606 ◽  
Author(s):  
Silvia Franceschi ◽  
Carlo La Vecchia ◽  
Fabio Parazzini ◽  
Monica Fasoli ◽  
Michela Regallo ◽  
...  
Keyword(s):  
Oral Contraceptives ◽  
Benign Breast Disease ◽  
Case Control Study ◽  
Breast Disease ◽  
Case Control ◽  
Control Study

Surface ultrastructure of danazol treated rat endometrium: A SEM study

1983 ◽  
Vol 41 ◽  
pp. 556-557
Author(s):  
R.P. Apkarian ◽  
J.S. Sanfilippo
Keyword(s):  
Cross Sections ◽  
Reproductive Tract ◽  
Preliminary Investigation ◽  
Breast Disease ◽  
Distal Segment ◽  
Uterine Horn ◽  
Female Reproductive Tract ◽  
Ultrastructural Changes ◽  
Cycle Phase ◽  
Sprague Dawley

The synthetic androgen danazol, is an isoxazol derivative of ethisterone. It is utilized in the treatment of endometriosis, fibrocystic breast disease, and has a potential use as a contraceptive. A study was designed to evaluate the ultrastructural changes associated with danazol therapy in a rat model. The preliminary investigation of the distal segment of the rat uterine horn was undertaken as part of a larger study intended to elucidate the effects of danazol on the female reproductive tract.Cross-sections (2-3 mm in length) of the distal segment of the uterine horn from sixteen Sprague-Dawley rats were prepared for SEM. Ten rats in estrus served as controls and six danazol treated rats were noted to have alterations of the estrus cycle i.e. a lag in cycle phase or noncycling patterns. Specimens were fixed in 3% glutaraldehyde in 0.05M phosphate buffer containing CaCl2 at pH 7.0-7.4 and chilled to 4°C. After a brief wash in distilled water, specimens were passed through a graded series of ethanol, critical point dryed in CO2 from absolute ethanol, and coated with 6nm Au. Observations were made with an IS1-40 SEM operated at 15kV.

Sign in / Sign up

Export Citation Format

Share Document