Mean Glandular Dose and Figure of Merit of 2 Dimensional and 3 Dimensional Imaging in Digital Breast Tomosynthesis

Average Absorbed Breast Dose (2ABD) to Mean Glandular Dose (MGD) Conversion Function for Digital Breast Tomosynthesis: A New Approach

Archives of Breast Cancer ◽

10.32768/abc.202183183-191 ◽

2021 ◽

pp. 183-191

Author(s):

‪Raffaele M Tucciariello ◽

Rocco Lamastra ◽

Patrizio Barca ◽

Marine Evelina Fantacci ◽

Antonio C Traino

Keyword(s):

Monte Carlo ◽

Digital Breast Tomosynthesis ◽

Dose Assessment ◽

Conversion Function ◽

Breast Tomosynthesis ◽

New Approach ◽

Mean Glandular Dose ◽

The Mean ◽

Good Agreement ◽

Dosimetric Index

Background: In this work a new method for the Mean Glandular Dose evaluation in digital breast tomosynthesis (DBT) is presented. Methods: Starting from the experimental-based dosimetric index, 2ABD, which represents the average absorbed breast dose, the mean glandular dose MGD2ABD was calculated using a conversion function of glandularity f(G), obtained through the use of Monte Carlo simulations.Results: f(G) was computed for a 4.5 cm thick breast: from its value MGD2ABD for different compressed breast thicknesses and glandularities was obtained. The comparison between MGD2ABD estimates and the dosimetric index provided in the current dosimetry protocols, following the Dance's approach, MGDDance, showed a good agreement (<10%) for all the analyzed breast thicknesses and glandularities. Conclusion: The strength of the proposed method can be considered an accurate mean glandular dose assessment starting from few and accessible parameters, reported in the header DICOM of each DBT exam.

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Breast Mass Characterization Using 3-Dimensional Automated Ultrasound as an Adjunct to Digital Breast Tomosynthesis

Journal of Ultrasound in Medicine ◽

10.7863/jum.2013.32.1.93 ◽

2013 ◽

Vol 32 (1) ◽

pp. 93-104 ◽

Cited By ~ 17

Author(s):

Frederic Padilla ◽

Marilyn A. Roubidoux ◽

Chintana Paramagul ◽

Sumedha P. Sinha ◽

Mitchell M. Goodsitt ◽

...

Keyword(s):

Digital Breast Tomosynthesis ◽

Breast Mass ◽

Breast Tomosynthesis ◽

3 Dimensional

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Comparison of mean glandular dose values provided by a digital breast tomosynthesis system in Brazil

Applied Radiation and Isotopes ◽

10.1016/j.apradiso.2014.10.004 ◽

2015 ◽

Vol 100 ◽

pp. 91-95

Author(s):

Bruno Beraldo Oliveira ◽

Lucas Paixão ◽

Sabrina Donato da Silva ◽

Maria Helena Araújo Teixeira ◽

Maria do Socorro Nogueira

Keyword(s):

Digital Breast Tomosynthesis ◽

Breast Tomosynthesis ◽

Mean Glandular Dose

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Digital breast tomosynthesis: Mean glandular dose estimation using monte carlo code

Physica Medica ◽

10.1016/j.ejmp.2016.07.224 ◽

2016 ◽

Vol 32 ◽

pp. 326

Author(s):

E. Tzamicha ◽

A. Dimitriadis ◽

H. Gonis ◽

E. Georgiou ◽

V. Tsapaki ◽

...

Keyword(s):

Monte Carlo ◽

Digital Breast Tomosynthesis ◽

Monte Carlo Code ◽

Dose Estimation ◽

Breast Tomosynthesis ◽

Mean Glandular Dose

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Mean glandular dose estimation using MCNPX for a digital breast tomosynthesis system with tungsten/aluminum and tungsten/aluminum+silver x-ray anode-filter combinations

Medical Physics ◽

10.1118/1.3002310 ◽

2008 ◽

Vol 35 (12) ◽

pp. 5278-5289 ◽

Cited By ~ 24

Author(s):

Andy K. W. Ma ◽

Dimitra G. Darambara ◽

Alexander Stewart ◽

Spencer Gunn ◽

Edward Bullard

Keyword(s):

Digital Breast Tomosynthesis ◽

Dose Estimation ◽

Breast Tomosynthesis ◽

X Ray ◽

Mean Glandular Dose ◽

And Tungsten

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Breast compression parameters among women screened with standard digital mammography and digital breast tomosynthesis in a randomized controlled trial

Acta Radiologica ◽

10.1177/0284185119863989 ◽

2019 ◽

Vol 61 (3) ◽

pp. 321-330 ◽

Cited By ~ 2

Author(s):

Gunvor Gipling Waade ◽

Åsne Holen ◽

Sofie Sebuødegård ◽

Hildegunn Aase ◽

Kristin Pedersen ◽

...

Keyword(s):

Digital Mammography ◽

Controlled Trial ◽

Digital Breast Tomosynthesis ◽

Compression Pressure ◽

Breast Tomosynthesis ◽

Breast Compression ◽

Randomized Controlled ◽

Mean Glandular Dose ◽

Evidence Based Guidelines ◽

Breast Thickness

Background No evidence-based guidelines regarding optimal breast compression in mammography exist, neither for standard digital mammography nor for digital breast tomosynthesis. Purpose To compare breast compression parameters and mean glandular dose in a randomized controlled trial with digital mammography versus digital breast tomosynthesis. Material and Methods We used information from 21,729 women aged 50–69 years, who participated in the To-Be trial, as part of BreastScreen Norway, 2016–2017. Information was obtained from the DICOM header and by assessing the images in an automated software for density estimation (VolparaDensity). Using linear regression, we investigated the effect of screening technique on breast compression parameters; compression force (N), compression pressure (kPa), and compressed breast thickness (mm), and mean glandular dose (mGy), by view (craniocaudal [CC] and mediolateral oblique [MLO]). We adjusted for age, breast volume and fibroglandular volume. Results A total of 11,056 (50.9%) women were screened with digital mammography and 10,673 (49.1%) with digital breast tomosynthesis. Adjusted regression analysis showed that women undergoing digital mammography received higher compression forces than women undergoing digital breast tomosynthesis (CC: –4.7 N; MLO: –1.1 N, P < 0.001 for both), higher compression pressure (CC: –1.0 k Pa; MLO: –0.1 kPa, P < 0.001 for both), and higher values of compressed breast thickness in the MLO view (–0.3 mm, P = 0.02). The women undergoing digital mammography received a lower mean glandular dose than women undergoing digital breast tomosynthesis ([+]0.06 mGy, P < 0.001). Conclusion Women undergoing digital breast tomosynthesis received lower compression force, compression pressure, and compressed breast thickness in MLO view, compared to women undergoing digital mammography. Further studies should investigate the impact of breast compression on image quality, screening outcome, and radiation dose for digital mammography and digital breast tomosynthesis in order to establish evidence-based guidelines for breast compression.

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Comparison of Mean Glandular Dose between Full-Field Digital Mammography and Digital Breast Tomosynthesis

Healthcare ◽

10.3390/healthcare9121758 ◽

2021 ◽

Vol 9 (12) ◽

pp. 1758

Author(s):

Kar Choon Teoh ◽

Hanani Abdul Manan ◽

Norhashimah Mohd Norsuddin ◽

Iqbal Hussain Rizuana

Keyword(s):

Digital Mammography ◽

Digital Breast Tomosynthesis ◽

Breast Tomosynthesis ◽

Full Field ◽

Mean Glandular Dose ◽

Full Field Digital Mammography ◽

Dose Monitoring ◽

Significant Difference ◽

Radiation Induced ◽

Breast Thickness

Early detection of breast cancer is diagnosed using mammography, the gold standard in breast screening. However, its increased use also provokes radiation-induced breast malignancy. Thus, monitoring and regulating the mean glandular dose (MGD) is essential. The purpose of this study was to determine MGD for full-field digital mammography (FFDM) and digital breast tomosynthesis (DBT) in the radiology department of a single centre. We also analysed the exposure factors as a function of breast thickness. A total of 436 patients underwent both FFDM and DBT. MGD was auto calculated by the mammographic machine for each projection. Patients’ data included compressed breast thickness (CBT), peak kilovoltage (kVp), milliampere-seconds (mAs) and MGD (mGy). Result analysis showed that there is a significant difference in MGD between the two systems, namely FFDM and DBT. However, the MGD values in our centre were comparable to other centres, as well as the European guideline (<2.5 mGy) for a standard breast. Although DBT improves the clinical outcome and quality of diagnosis, the risk of radiation-induced carcinogenesis should not be neglected. Regular quality control testing on mammography equipment must be performed for dose monitoring in women following a screening mammography in the future.

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Comparison Of Spectra and Mean Glandular Dose With Tube Voltages Used in Digital Breast Tomosynthesis From Simulated, Metrological and Clinical Cases

Radiation Protection Dosimetry ◽

10.1093/rpd/ncaa198 ◽

2020 ◽

Author(s):

Leandro Barbosa da Silveira Gatto ◽

Delson Braz ◽

Leonardo Pacifico ◽

Paulo Travassos ◽

Luis Alexandre Goncalves Magalhaes

Keyword(s):

Monte Carlo ◽

Radiation Dose ◽

Digital Breast Tomosynthesis ◽

High Energy ◽

High Energy Resolution ◽

Semiconductor Detectors ◽

Diagnostic Modality ◽

Breast Tomosynthesis ◽

X Ray ◽

Mean Glandular Dose

Abstract Digital breast tomosynthesis (DBT) is a screening and diagnostic modality that acquires images of a breast at multiple angles during a short scan. The Selenia Dimensions (Hologic, Bedford, Mass) DBT system can perform both full-field digital mammography and DBT. The system acquires 25 projections over a 15° angular range (from −7.5° to +7.5°). X-ray spectroscopy is generally linked with a high-resolution semiconductor detector through a correction to its energy response function. The energy spectrum describes the radiation field, in which several quality parameters can be extracted, such as the effective energy, half-value layer and exposure. X-ray spectroscopy is usually performed with solid-state semiconductor detectors. Radiation dose is a concern in mammography, as the current protocols recommend that medical physicians evaluate mean glandular dose (MGD) as a part of service quality control. Studies are needed for radiation dose optimization from tomosynthesis patients. The COMET metrological X-ray tube, considered as with a constant potential and cooled, has proved to be a crucial tool in order to obtain the high energy resolution for low-energy radiographs in mammography. The Monte Carlo method, through Monte Carlo N-Particle eXtended (MCNPX), was proven to be an essential tool for image formation and posterior analysis of the deposited dose from breast simulators and radiographic contrast evaluation, for several anode/filter combinations. The purpose of this work was to assess the MGD and spectra in slabs of polymethyl methacrylate (PMMA) and breast equivalent thicknesses using four experiments with a Hologic Selenia Dimensions mammography X-ray tube with multimeter, a spectrometer (only for spectra, in this case), a metrological X-ray tube with a multimeter, and the MCNPX code. References indicate that the real conditions for a mammography X-ray tube that conducts tomosynthesis include tube voltages of 26, 29, 30 and 33 kVp. Taking into account several thicknesses of PMMA, both the MGD and spectral results were in accordance with the references. Most of the spectra were in accordance with the references, showing that the resources used in the experiments can evaluate the energy level received by a patient. The MGD values were lower than those in the references from 30 to 50 mm PMMA, and the data can be used for improvements in the detectors used in the Laboratory of Metrology in the State of Rio de Janeiro University, Brazil. Additionally, in the future, optimization of image quality can be performed for both semiconductors and mammography X-ray equipment.

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